Now showing items 1-20 of 532

    • Graft fixation influences revision risk after ACL reconstruction with hamstring tendon autografts : A study of 38,666 patients from the Scandinavian knee ligament registries 2004–2011 

      Persson, Andreas; Gifstad, Tone; Lind, Martin; Engebretsen, Lars; Fjeldsgaard, Knut; Drogset, Jon Olav; Forssblad, Magnus; Espehaug, Birgitte; Kjellsen, Asle; Fevang, Jonas Meling (Taylor & Francis, 2018)
      Background and purpose — A large number of fi xation methods of hamstring tendon autograft (HT) are available for anterior cruciate ligament reconstruction (ACLR). Some studies report an association between fi xation ...
      Journal article
    • Similar migration in computer-assisted and conventional total knee arthroplasty 

      Petursson, Gunnar; Fenstad, Anne Marie; Gøthesen, Øystein; Haugan, Kristin; Dyrhovden, Gro Sævik; Halland, Geir; Röhrl, Stephan Maximillian; Aamodt, Arild; Nilsson, Kjell G.; Furnes, Ove (Taylor & Francis, 2017)
      Background and purpose — Computer-assisted surgery (CAS) in total knee arthroplasty (TKA) has been used in recent years in the hope of improving the alignment and positioning of the implant, thereby achieving a better ...
      Journal article
    • Molecular Subtypes of Breast Cancer: Long-term Incidence Trends and Prognostic Differences 

      Valla, Marit; Vatten, Lars Johan; Engstrøm, Monica J; Haugen, Olav Anton; Akslen, Lars A.; Bjørngaard, Johan Håkon; Hagen, Anne Irene; Ytterhus, Borgny; Bofin, Anna M.; Opdahl, Signe (American Association for Cancer Research, 2016-12)
      Background: Secular trends in incidence and prognosis of molecular breast cancer subtypes are poorly described. We studied long-term trends in a population of Norwegian women born 1886–1977. Methods: A total of ...
      Journal article
    • FGD5 amplification in breast cancer patients is associated with tumor proliferation and a poorer prognosis 

      Valla, Marit; Engstrøm, Monica J; Ytterhus, Borgny; Hansen, Åse Kristin Skain; Akslen, Lars A.; Vatten, Lars Johan; Opdahl, Signe; Bofin, Anna M. (Springer, 2017-04)
      Purpose: Proliferation is a hallmark of cancer. Using a combined genomic approach, FGD5 amplification has been identified as a driver of proliferation in Luminal breast cancer. We aimed to describe FGD5 copy number change ...
      Journal article
    • A short endoscopic Secretin test for the diagnosis of chronic pancreatitis 

      Erchinger, Friedemann Georg (The University of Bergen, 2018-06-12)
      Background: The diagnosis of CP is not yet clearly defined. Many national guidelines exist, but - as in many other not clearly defined diseases - there is no worldwide consensus. In CP, evaluation of exocrine pancreatic ...
      Doctoral thesis
    • Cancer-Associated troke: The Bergen NORSTROKE Study 

      Selvik, Henriette Aurora; Thomassen, Lars; Bjerkreim, Anna Therese; Næss, Halvor (Karger, 2015-10-13)
      Background: Underlying malignancy can cause ischemic stroke in some patients. Mechanisms include the affection of the coagulation cascade, tumor mucin secretion, infections and nonbacterial endocarditis. The release of ...
      Journal article
    • Risk factors influencing long-term survival and nursing home placement in stroke survivors and patients with carotid stenosis 

      Mathisen, Sara Maria (The University of Bergen, 2018-01-11)
      Risk factors influencing long-term survival and nursing home placement in stroke survivors and patients with carotid stenosis Stroke is one of the leading causes of mortality and morbidity worldwide and one of the most ...
      Doctoral thesis
    • Cancer-Associated Ischemic Stroke: The Bergen NORSTROKE Study 

      Selvik, Henriette Aurora (The University of Bergen, 2018-05-25)
      Background: Stroke and cancer are both leading causes of death and disability in the Western world. Cancer can lead to a hypercoagulable state that can cause ischemic stroke. Mechanisms include disturbance of the coagulation ...
      Doctoral thesis
    • Bowel function and quality of life after superior mesenteric nerve plexus transection in right colectomy with D3 extended mesenterectomy 

      Thorsen, Yngve; Stimec, Bojan V.; Andersen, Solveig Norheim; Lindstrøm, Jonas Christoffer; Pfeffer, Frank; Øresland, Tom; Ignjatovic, Dejan; RCC Study Group (Springer, 2016)
      Background: The aim of this study was to ascertain the impact of injury to the superior mesenteric nerve plexus caused by right colectomy with D3 extended mesenterectomy as performed in the prospective multicenter trial: ...
      Journal article
    • Evaluation of a guided self-help intervention for irritable bowel syndrome - An interdisciplinary approach 

      Andersen, Mari Liltvedt (The University of Bergen, 2017-12-16)
      Background: Irritable bowel syndrome (IBS) is the most common functional gastrointestinal disorder, defined by recurrent abdominal pain or discomfort, associated with defecation and/or altered bowel habits. Due to the lack ...
      Master thesis
    • Randomized Controlled Trial of Extended Perioperative Counseling in Enhanced Recovery After Colorectal Surgery 

      Forsmo, Håvard Mjørud; Erichsen, Christian; Rasdal, Anne; Tvinnereim, Jon Meyer; Körner, Hartwig; Pfeffer, Frank (Wolters Kluwer, 2018-06)
      BACKGROUND: Enhanced recovery after surgery programs reduce the length of hospital stay in patients who undergo elective colorectal resection, but the reasons for this reduction are not well understood. OBJECTIVE: The aim ...
      Journal article
    • Epidemiology of benign external hydrocephalus in Norway - a population-based study 

      Wiig, Ulrikke S.; Zahl, Sverre Morten; Egge, Arild; Helseth, Eirik; Wester, Knut (Elsevier, 2017-08)
      Background: Benign external hydrocephalus is defined as a rapidly increasing head circumference (occipitofrontal circumference) with characteristic radiological findings of increased subarachnoid cerebrospinal fluid spaces ...
      Journal article
    • C77G in PTPRC (CD45) is no risk allele for ovarian cancer, but associated with less aggressive disease 

      Landskron, Johannes; Kraggerud, Sigrid M.; Wik, Elisabeth; Dørum, Anne; Bjørnslett, Merete Pauline; Melum, Espen; Helland, Øystein; Bjørge, Line; Lothe, Ragnhild A; Salvesen, Helga; Tasken, Kjetil (PLOS, 2017-07-31)
      The pan lymphocyte marker CD45 exists in various isoforms arising from alternative splicing of the exons 4, 5 and 6. While naïve T cells express CD45RA translated from an mRNA containing exon 4, exons 4–6 are spliced out ...
      Journal article
    • Type 2 diabetes genes : present status and data from Norwegian studies 

      Hertel, Jens Kristoffer; Johansson, Stefan; Midthjell, Kristian; Nygård, Ottar; Njølstad, Pål Rasmus; Molven, Anders (Norsk forening for epidemiologi, 2013)
      The worldwide rise in prevalence of type 2 diabetes has led to an intense search for the genetic risk factors of this disease. In type 2 diabetes and other complex disorders, multiple genetic and environmental factors, as ...
      Journal article
    • The mediating effect of body mass index on the relationship between smoking and hip or knee replacement due to primary osteoarthritis. A population-based cohort study (the HUNT study) 

      Johnsen, Marianne Bakke; Hellevik, Alf Inge; Småstuen, Milada C; Langhammer, Arnulf; Furnes, Ove; Flugsrud, Gunnar B; Nordsletten, Lars; Zwart, John-Anker; Storheim, Kjersti (PLOS, 2017-12-28)
      To investigate the total effect of smoking on total hip or knee replacement (THR/TKR) due to primary osteoarthritis (OA) and to quantify the indirect effect of smoking through body mass index (BMI). Participants from the ...
      Journal article
    • The causal role of smoking on the risk of hip or knee replacement due to primary osteoarthritis: a Mendelian randomisation analysis of the HUNT study 

      Johnsen, Marianne Bakke; Vie, Gunnhild Åberge; Winsvold, Bendik K S; Bjørngaard, Johan Håkon; Åsvold, Bjørn Olav; Gabrielsen, Maiken Elvestad; Pedersen, Linda Margareth; Hellevik, Alf Inge; Langhammer, Arnulf; Furnes, Ove; Flugsrud, Gunnar B; Skorpen, Frank; Romundstad, Pål Richard; Storheim, Kjersti; Nordsletten, Lars; Zwart, John-Anker (Elsevier, 2017-06)
      Objective: Smoking has been associated with a reduced risk of hip and knee osteoarthritis (OA) and subsequent joint replacement. The aim of the present study was to assess whether the observed association is likely to be ...
      Journal article
    • Incidence of total hip or knee replacement due to osteoarthritis in relation to thyroid function: a prospective cohort study (The Nord-Trøndelag Health Study) 

      Hellevik, Alf Inge; Johnsen, Marianne Bakke; Langhammer, Arnulf; Fenstad, Anne Marie; Furnes, Ove; Storheim, Kjersti; Zwart, John-Anker; Flugsrud, Gunnar B; Nordsletten, Lars (BioMed Central, 2017-05-18)
      Background: To study whether thyroid function was associated with risk of hip or knee replacement due to primary osteoarthritis. Methods: In a prospective cohort study, data from the second and third survey of the ...
      Journal article
    • The Pharmacogenomics of Bipolar Disorder study (PGBD): Identification of genes for lithium response in a prospective sample 

      Ødegaard, Ketil Joachim; Alda, Martin; Anand, Anit; Andreassen, Ole Andreas; Balaraman, Yokesh; Berrettini, Wade H.; Bhattacharjee, Abesh; Brennand, Kristen J.; Burdick, Katherine E.; Calabrese, Joseph R.; Calkin, Cynthia V.; Claasen, Ana; Coryell, William H.; Craig, David; DeModena, Anna; Frye, Mark A.; Gage, Fred H.; Gao, Keming; Garnham, Julie; Gershon, Elliot; Jakobsen, Petter; Leckband, Susan G.; McCarthy, Michael J.; McInnis, Melvin G.; Maihofer, Adam X.; Mertens, Jerome; Morken, Gunnar; Nievergelt, Caroline M.; Nurnberger, John I.; Pham, Son; Schøyen, Helle Kristine; Shekhtman, Tatyana; Shilling, Paul D.; Szelinger, Szabolcs; Tarwater, Bruce; Yao, Jun; Zandi, Peter P.; Kelsoe, John R. (BioMed Central, 2016-05-05)
      Background: Bipolar disorder is a serious and common psychiatric disorder characterized by manic and depressive mood switches and a relapsing and remitting course. The cornerstone of clinical management is stabilization ...
      Journal article
    • Negotiating the boundaries of psychosis: A qualitative studyof the service provider perspective on treatment delay incommunity mental health 

      Kvig, Erling Inge; Moe, Cathrine Fredriksen; Brinchmann, Beate; Larsen, Tor Ketil; Sørgaard, Knut W. (Wiley, 2017)
      Aim: Evidence shows that many patients are detected and treated late in their course of illness, and that substantial delay occurs even after entry to mental health services. Although several studies have examined the ...
      Journal article
    • Fourteen sequence variants that associate with multiple sclerosis discovered by meta-analysis informed by genetic correlations 

      Olafsson, S.; Stridh, P.; Bos, Steffan Daniel; Ingason, Andrés; Euesden, J; Sulem, Patrick; Thorleifsson, Gudmar; Gustafsson, O; Geirsson, AJ; Jóhannesson, Ari J.; Thorsson, AV; Ludviksson, BR; Sigurgeirsson, Bardur; Jonasson, JG; Olafsson, E; Kristjansdottir, H; Olafsson, JH; Orvar, KB; Benediktsson, Rafn; Bjarnason, Ragnar; Kristjansdottir, Sjofn; Gislason, Thorarin; Valdimarsson, T; Mikaelsdottir, E; Sigurdsson, S; Jonsson, S; Rafnar, Thorunn; Aarsland, Dag; Djurovic, Srdjan; Fladby, Tormod; Knudsen, Gun Peggy S.; Celius, Elisabeth Gulowsen; Myhr, Kjell-Morten; Gröndal, Gerdur; Steinsson, K; Valdimarsson, Helgi; Bjornsson, Sigurdur; Bjornsdottir, US; Bjornsson, Einar S.; Nilsson, B; Andreassen, Ole Andreas; Alfredsson, Lars; Hillert, Jan; Kockum, Ingrid; Másson, Gísli; Thorsteinssdottir, U; Gudbjartsson, Daniel F.; Stefansson, H; Hjaltason, H; Harbo, Hanne Flinstad; Olsson, T; Jonsdottir, I; Stefansson, K (Nature Publishing Group, 2017)
      A meta-analysis of publicly available summary statistics on multiple sclerosis combined with three Nordic multiple sclerosis cohorts (21,079 cases, 371,198 controls) revealed seven sequence variants associating with multiple ...
      Journal article