Blar i Department of Clinical Medicine på tittel
Viser treff 222-241 av 2095
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The cannabis pathway to non-affective psychosis may reflect less neurobiological vulnerability
(Peer reviewed; Journal article, 2014-11-18)There is a high prevalence of cannabis use reported in non-affective psychosis. Early prospective longitudinal studies conclude that cannabis use is a risk factor for psychosis, and neurochemical studies on cannabis have ... -
Capillary leakage in post-cardiac arrest survivors during therapeutic hypothermia - a prospective, randomised study
(Peer reviewed; Journal article, 2010-05-25)Background: Fluids are often given liberally after the return of spontaneous circulation. However, the optimal fluid regimen in survivors of cardiac arrest is unknown. Recent studies indicate an increased fluid requirement ... -
Carboxyl ester lipase in pancreatic disease : In vitro and in vivo studies of human pathogenic CEL mutations
(Doctoral thesis, 2023-03-21)Karboksylester-lipase (CEL) er et fordøyelsesenzym som hovedsakelig er uttrykt i bukspytt-kjertelen. Det siste eksonet i CEL-genet inneholder et variabelt antall tandem repetisjoner (VNTR), altså en region av repeterte ... -
Carboxyl-ester lipase in human pancreatic disease. A study with focus on genetics, glycosylation and ABO blood groups
(Doctoral thesis, 2018-09-28)Glycosylation is a post-translational modification where carbohydrates are attached to a protein or other organic molecule. Defects in glycosylation are seen in many human pathologies and may even be the underlying cause ... -
Cardiac Arrest in a Community: Epidemiology, Treatment, and Outcome
(Doctoral thesis, 2017-09-01)Background: Incidence and mortality from sudden cardiac arrest is high, making it a prevalent cause of death. Both incidence and survival rates show great variability between populations. In order to improve survival from ... -
Cardiac Structure and Function in Epilepsy Patients with Drug-Resistant Convulsive Seizures
(Journal article; Peer reviewed, 2022)High frequency of convulsive seizures and long-lasting epilepsy are associated with an increased risk of sudden unexpected death in epilepsy (SUDEP). Structural changes in the myocardium have been described in SUDEP victims. ... -
Cardiac Structure and Function in Epilepsy Patients with Drug-Resistant Convulsive Seizures
(Journal article; Peer reviewed, 2022)High frequency of convulsive seizures and long-lasting epilepsy are associated with an increased risk of sudden unexpected death in epilepsy (SUDEP). Structural changes in the myocardium have been described in SUDEP victims. ... -
Cardiovascular changes in young renal failure patients
(Journal article; Peer reviewed, 2021)Progresses in medical care of severe kidney disease and congenital anomalies of kidney and urinary tract make it possible for a higher percentage of young renal failure patients to survive and enter adulthood. There is ... -
Carotid intima-media thickness and cerebrovascular vasoreactivity in patients with intracranial aneurysms : A sonographic study of potential predictors for aneurysm rupture risk and delayed cerebral ischemia
(Doctoral thesis, 2020-04-03)Background and aims Intracranial aneurysms can rupture and cause an aneurysmal subarachnoid hemorrhage (aSAH), a bleeding under the arachnoid meninges covering the brain. This is a devastating event, in which delayed ... -
Case Report: Limbic encephalitis following treatment with durvalumab for small-cell lung cancer
(Journal article; Peer reviewed, 2023-10-16)Background: Durvalumab is an immune checkpoint Inhibitor (ICIs) that is used in the treatment of malignant tumors, such as lung cancer and melanoma. ICIs are associated with immune-related adverse events including autoimmune ... -
Case report: Pain in anti-DPPX encephalitis
(Journal article; Peer reviewed, 2022)Encephalitis due to antibodies targeting dipeptidyl-peptidase-like protein 6 (DPPX), a potassium channel subunit, is rare. The illness is typically characterized by a triad of weight loss, CNS hyperexcitability and cognitive ... -
Case Report: Polyvinylpyrrolidone deposition disease from repeated injection of opioid substitution drugs: Report of a case with a fatal outcome
(Journal article; Peer reviewed, 2021)Background: Intravenous injection of oral opioid substitution drugs (OSD) is widespread among injecting drug users. Several OSDs contain the polymer polyvinylpyrrolidone (PVP) as an excipient. Parenterally administered PVP ... -
Case report: Seropositive myasthenia gravis complicated by limbic encephalitis positive for antibodies to AMPAR and Lgi1
(Journal article; Peer reviewed, 2023-10-12)Objectives: Autoantibodies to the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) and leucine-rich glioma-inactivated 1 (Lgi1) are associated with autoimmune encephalitis. We described an acetylcholine ... -
Case-control study of food intake, nausea and vomiting of pregnant women
(Master thesis, 2014-05-15)Background: Severe pregnancy induced nausea and vomiting, also known as Hyperemesis gravidarum (HG), can lead to significant reduced quality of life (QOL) and of food intake. Untreated this can potentially harm both mother ... -
Causal modelling of variation in clinical practice and long-term outcomes of ADHD using Norwegian registry data: The ADHD controversy project
(Journal article; Peer reviewed, 2021)Introduction Attention-deficit/hyperactivity disorder (ADHD) is among the most common mental disorders in children and adolescents, and it is a strong risk factor for several adverse psychosocial outcomes over the lifespan. ... -
The causal role of smoking on the risk of hip or knee replacement due to primary osteoarthritis: a Mendelian randomisation analysis of the HUNT study
(Peer reviewed; Journal article, 2017-06)Objective: Smoking has been associated with a reduced risk of hip and knee osteoarthritis (OA) and subsequent joint replacement. The aim of the present study was to assess whether the observed association is likely to be ... -
Cd11c‐cd8 spatial cross presentation: A novel approach to link immune surveillance and patient survival in soft tissue sarcoma
(Journal article; Peer reviewed, 2021)Checkpoint inhibitors are slowly being introduced in the care of specific sarcoma subtypes such as undifferentiated pleomorphic sarcoma, alveolar soft part sarcoma, and angiosarcoma even though formal indication is lacking. ... -
CD47 and CD68 expression in breast cancer is associated with tumor-infiltrating lymphocytes, blood vessel invasion, detection mode, and prognosis
(Journal article; Peer reviewed, 2023)CD47 expressed on tumor cells binds to signal regulatory protein alpha on macrophages, initiating inhibition of phagocytosis. We investigated the relationships between tumor expression of CD47 and CD68 macrophage content, ... -
CDR2 antigen and Yo antibodies
(Peer reviewed; Journal article, 2011)Paraneoplastic cerebellar degeneration (PCD) is often associated with Yo antibodies that are directed against human cerebellar degeneration-related protein 2 (CDR2). Such antibodies may also be found in ovarian cancer ... -
CDR2L Is the Major Yo Antibody Target in Paraneoplastic Cerebellar Degeneration
(Peer reviewed; Journal article, 2019)The pathogenesis of Yo‐mediated paraneoplastic cerebellar degeneration (PCD) is unclear. We applied cerebrospinal fluid and serum from PCD patients as well as CDR2 and CDR2L antibodies to neuronal tissue, cancer cell lines, ...