Blar i Department of Clinical Medicine på tittel
Viser treff 291-310 av 2095
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Cleavage of the urokinase receptor (uPAR) on oral cancer cells: Regulation by transforming growth factor - beta1 (TGF-beta1) and potential effects on migration and invasion
(Peer reviewed; Journal article, 2017-05-19)Background: Urokinase plasminogen activator (uPA) receptor (uPAR) is up-regulated at the invasive tumour front of human oral squamous cell carcinoma (OSCC), indicating a role for uPAR in tumour progression. We previously ... -
Clinical and histological characterization of oral pemphigus lesions in patients with skin diseases: a cross sectional study from Sudan
(Peer reviewed; Journal article, 2013-11-21)Background: Pemphigus is a rare group of life-threatening mucocutaneous autoimmune blistering diseases. Frequently, oral lesions precede the cutaneous ones. This study aimed to describe clinical and histological features ... -
Clinical and molecular studies of disease caused by mutations of the mitochondrial DNA polymerase gamma (POLG).
(Doctoral thesis, 2010-11-26)Background: Mutations in the gene encoding the DNA-polymerase gamma (POLG), the enzyme that replicates and repairs the mitochondrial genome, are an important cause of human disease and disability. Over 130 pathogenic ... -
Clinical and MRI findings in lumbar spinal stenosis: baseline data from the NORDSTEN study
(Journal article; Peer reviewed, 2021)Purpose: The aim was to describe magnetic resonance imaging findings in patients planned for lumbar spinal stenosis surgery. Further, to describe possible associations between MRI findings and patient characteristics with ... -
Clinical and prognostic associations of autoantibodies recognizing adrenergic/muscarinic receptors in patients with heart failure
(Journal article; Peer reviewed, 2023)Aims The importance of autoantibodies (AABs) against adrenergic/muscarinic receptors in heart failure (HF) is not well-understood. We investigated the prevalence and clinical/prognostic associations of four AABs recognizing ... -
Clinical aspects in the late stage of whiplash injury
(Doctoral thesis, 2009-11-13) -
Clinical characteristics in patients with cervicogenic dizziness: A systematic review
(Peer reviewed; Journal article, 2019)Background and aims: Cervicogenic dizziness (CD) is a clinical syndrome of dizziness associated with neck dysfunction. CD represents a considerable diagnostic challenge since dizziness and neck pain are common symptoms ... -
Clinical Disease Progression in Parkinson’s Disease
(Doctoral thesis, 2006-10-06) -
Clinical effect modifiers of antibiotic treatment in patients with chronic low back pain and Modic changes - secondary analyses of a randomised, placebocontrolled trial (the AIM study)
(Journal article; Peer reviewed, 2020)Background Randomised trials on antibiotic treatment for patients with chronic low back pain and vertebral endplate changes visible on MRI (Modic changes) have shown mixed results. A possible explanation might be a real ... -
Clinical Efficacy and Safety of Bevacizumab Monotherapy in Patients with Metastatic Melanoma: Predictive Importance of Induced Early Hypertension
(Peer reviewed; Journal article, 2012-06-15)Background: VEGF driven angiogenesis plays a key role in cancer progression. We determined the clinical efficacy of bevacizumab monotherapy in patients with metastatic melanoma. Methods and Findings: Thirty-five patients ... -
Clinical Efficacy of Combined Surgical Patient Safety System and the World Health Organization’s Checklists in Surgery. A Nonrandomized Clinical Trial
(Peer reviewed; Journal article, 2020)Importance: Checklists have been shown to improve patient outcomes in surgery. The intraoperatively used World Health Organization surgical safety checklist (WHO SSC) is now mandatory in many countries. The only evidenced ... -
The Clinical Frailty Scale for mortality prediction of old acutely admitted intensive care patients: a meta-analysis of individual patient-level data
(Journal article; Peer reviewed, 2023)Background This large-scale analysis pools individual data about the Clinical Frailty Scale (CFS) to predict outcome in the intensive care unit (ICU). Methods A systematic search identified all clinical trials that ... -
Clinical insight among persons with schizophrenia spectrum disorders treated with amisulpride, aripiprazole or olanzapine: a semi-randomised trial
(Journal article; Peer reviewed, 2023)Background Antipsychotic treatment may improve clinical insight. However, previous studies have reported inconclusive findings on whether antipsychotics improve insight over and above the reduction in symptoms of ... -
Clinical Management of Pancreatic Premalignant Lesions
(Journal article; Peer reviewed, 2022) -
Clinical Management of Vestibular Schwannoma : The V-REX randomized trial and other clinical studies on vestibular schwannoma
(Doctoral thesis, 2024-01-20)Introduksjon: Vestibularis schwannomer (VS) er godartede svulster som utgår fra de Schwannske cellene rundt den åttende hjernenerven og utgjør ca. 8% av alle intrakranielle neoplasmer. Behandlingsalternativene er mikrokirurgisk ... -
Clinical manifestation of acute cerebral infarcts in multiple arterial territories
(Journal article; Peer reviewed, 2021)Objectives: We aimed to assess frequencies and radiological aspects of single- and multiterritory clinical manifestation among patients with acute cerebral infarcts in multiple arterial territories (MACI). Materials & ... -
Clinical outcome after mosaicplasty of knee articular cartilage defects of patellofemoral joint versus tibiofemoral joint
(Journal article; Peer reviewed, 2020)Background The purpose was to investigate survival of cartilage repair in the knee joint by osteochondral autograft transfer stratified by location of the lesion; patellofemoral joint (N = 26) versus the medial or lateral ... -
Clinical outcome after surgery for lumbarspinal stenosis in patients with insignificantlower extremity pain. A prospective cohortstudy from the Norwegian registry for spine surgery
(Peer reviewed; Journal article, 2019-01-22)Background: Spinal stenosis is a clinical diagnosis in which the main symptom is pain radiating to the lower extremities, or neurogenic claudication. Radiological spinal stenosis is commonly observed in the population and ... -
Clinical outcome measures in dementia with Lewy bodies trials: critique and recommendations
(Journal article; Peer reviewed, 2022)The selection of appropriate outcome measures is fundamental to the design of any successful clinical trial. Although dementia with Lewy bodies (DLB) is one of the most common neurodegenerative conditions, assessment of ... -
Clinical patterns of presentation and attenuated inflammatory response in octo- and nonagenarians with perforated gastroduodenal ulcers
(Peer reviewed; Journal article, 2016-08)Background. Perforated gastrodudenal ulcer (PGDU) is an operative emergency with high mortality rates. The growing elderly populationincreasingly presents with need for geriatric acute operative care. Current knowledge of ...