Blar i Department of Clinical Medicine på emneord "DNA methylation"

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    • Prognostic relevance of an epigenetic biomarker panel in sentinel lymph nodes from colon cancer patients 

      Lind, Guro Elisabeth; Guriby, Marianne; Ahlquist, Terje Cruickshank; Hussain, Israr; Jeanmougin, Marine; Søreide, Kjetil; Kørner, Hartwig; Lothe, Ragnhild A; Nordgård, Oddmund (Peer reviewed; Journal article, 2017-09-05)
      Background: Patients with early colorectal cancer (stages I–II) generally have a good prognosis, but a subgroup of 15–20% experiences relapse and eventually die of disease. Occult metastases have been suggested as a marker ...

    • Transgenerational and intergenerational epigenetic inheritance in allergic diseases 

      Knudsen, Gerd Toril Mørkve; Rezwan, Faisal I.; Jiang, Yu; Karmaus, Wilfried; Svanes, Cecilie; Holloway, John W. (Peer reviewed; Journal article, 2018-09)
      It has become clear that early life (including in utero exposures) is a key window of vulnerability during which environmental exposures can alter developmental trajectories and initiate allergic disease development. ...