Blar i Department of Clinical Medicine på emneord "Endometrial cancer"
Viser treff 1-4 av 4
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Hormone receptor loss in endometrial carcinoma curettage predicts lymph node metastasis and poor outcome in prospective multicentre trial
(Peer reviewed; Journal article, 2013-11)Background: Preoperative histologic examination of tumour tissue is essential when deciding if endometrial cancer surgery should include lymph node sampling. We wanted to investigate if biomarkers could improve prediction ... -
Impact of body mass index and fat distribution on sex steroid levels in endometrial carcinoma: A retrospective study
(Peer reviewed; Journal article, 2019-06-07)Background Obesity is an important cause of multiple cancer types, amongst which endometrial cancer (EC). The relation between obesity and cancer is complicated and involves alterations in insulin metabolism, response to ... -
KRAS gene amplification and overexpression but not mutation associates with aggressive and metastatic endometrial cancer
(Peer reviewed; Journal article, 2012)BACKGROUND: Three quarter of endometrial carcinomas are treated at early stage. Still, 15 to 20% of these patients experience recurrence, with little effect from systemic therapies. Homo sapiens v-Ki-ras2 Kirsten rat sarcoma ... -
The MDM4 SNP34091 (rs4245739) C-allele is associated with increased risk of ovarian—but not endometrial cancer
(Peer reviewed; Journal article, 2016-02-11)The MDM4 protein (also known as MDMX or HDMX) is a negative regulator of p53, not only by direct interaction but also through its interaction with MDM2. Further, MDM4 overexpression and amplification have been observed in ...