Blar i Department of Clinical Medicine på forfatter "Jakobsen, Petter"
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Affect Recognition in Muscular Response Signals
Boeker, Matthias; Jakobsen, Petter; Riegler, Michael; Stabell, Lena Antonsen; Fasmer, Ole Bernt; Halvorsen, Pål; Hammer, Hugo Lewi (Journal article; Peer reviewed, 2023)This study investigated the potential of recognising arousal in motor activity collected by wrist-worn accelerometers. We hypothesise that emotional arousal emerges from the generalised central nervous system which embeds ... -
Applying machine learning in motor activity time series of depressed bipolar and unipolar patients compared to healthy controls
Jakobsen, Petter; Garcia-Ceja, Enrique; Riegler, Michael; Stabell, Lena Antonsen; Nordgreen, Tine; Tørresen, Jim; Fasmer, Ole Bernt; Ødegaard, Ketil Joachim (Journal article; Peer reviewed, 2020)Current practice of assessing mood episodes in affective disorders largely depends on subjective observations combined with semi-structured clinical rating scales. Motor activity is an objective observation of the inner ... -
The association between lithium use and neurocognitive performance in patients with bipolar disorder
Burdick, Katherine E.; Millett, Caitlin E.; Russo, Manuela; Alda, Martin; Alliey-Rodriguez, Ney; Anand, Amit; Balaraman, Yokesh; Berrettini, Wade H.; Bertram, Holli; Calabrese, Joseph R.; Calkin, Cynthia V.; Conroy, Carla; Coryell, William; DeModena, Anna; Feeder, Scott; Fisher, Carrie; Frazier, Nicole; Frye, Mark; Gao, Keming; Garnham, Julie; Gershon, Elliot S.; Glazer, Kara; Goes, Fernando S.; Goto, Toyomi; Harrington, Gloria J.; Jakobsen, Petter; Kamali, Masoud; Kelly, Marisa; Leckband, Susan G.; Løberg, Else-Marie; Lohoff, Falk W.; Maihofer, Adam X.; McCarthy, Michael J.; McInnis, Melvin; Morken, Gunnar; Nievergelt, Caroline M.; Nurnberger, John I.; Oedegaard, Ketil J.; Ortiz, Abigail; Ritchey, Megan; Ryan, Kelly; Schinagle, Martha; Schwebel, Candice; Shaw, Martha; Shilling, Paul D.; Slaney, Claire; Stapp, Emma; Tarwater, Bruce; Zandi, Peter P.; Kelsoe, John R. (Journal article; Peer reviewed, 2020)Lithium remains the gold standard for the treatment of bipolar disorder (BD); however, its use has declined over the years mainly due to the side effects and the subjective experience of cognitive numbness reported by ... -
Challenges and possible solutions in cross-disciplinary and cross-sectorial research teams within the domain of e-mental health
Nordgreen, Tine; Rabbi, Fazle; Tørresen, Jim; Skar, Yngvar Sigmund; Guribye, Frode; Inal, Yavuz; Flobak, Eivind; Wake, Jo Dugstad; Mukhiya, Suresh Kumar; Aminifar, Amin; Myklebost, Sunniva Brurok; Lundervold, Astri J.; Kenter, Robin Maria Francisca; Hammar, Åsa Karin; Kahlon, Smiti; Nordby, Emilie; Sekse, Ragnhild Johanne Tveit; Griffin, Kristine Fonnes; Jakobsen, Petter; Pham, Hoang Minh; Côté-Allard, Ulysse Teller Masao; Noori, Farzan Majeed; Lamo, Yngve (Journal article; Peer reviewed, 2021)Purpose: Mental illness presents a huge individual, societal and economic challenges, currently accounting for 20% of the worldwide burden of disease. There is a gap between the need for and access to services. Digital ... -
Chronotype and cellular circadian rhythms predict the clinical response to lithium maintenance treatment in patients with bipolar disorder
McCarthy, Michael J.; Stautland, Andrea; Jakobsen, Petter; Ødegaard, Ketil Joachim; Andreassen, Ole Andreas; Djurovic, Srdjan; Morken, Gunnar; Schøyen, Helle Kristine; McInnis, Melvin G.; Alda, Martin; Gage, Fred H.; Calabrese, Joseph R.; Zandi, Peter P.; Nievergelt, Caroline M.; Shilling, Paul D.; Kelsoe, John R. (Peer reviewed; Journal article, 2019)Bipolar disorder (BD) is a serious mood disorder associated with circadian rhythm abnormalities. Risk for BD is genetically encoded and overlaps with systems that maintain circadian rhythms. Lithium is an effective mood ... -
Clinical predictors of non-response to lithium treatment in the Pharmacogenomics of Bipolar Disorder (PGBD) study
Lin, Yan; Maihofer, Adam X.; Stapp, Emma; Ritchey, Megan; Alliey-Rodriguez, Ney; Anand, Amit; Balaraman, Yokesh; Berrettini, Wade H; Bertram, Holli; Bhattacharjee, Abesh; Calkin, Cynthia V.; Conroy, Carla; Coryell, William; D´Arcangelo, Nicole; DeModena, Anna; Biernacka, Joanna M.; Fisher, Carrie; Frazier, Nicole; Frye, Mark; Gao, Keming; Garnham, Julie; Gershon, Elliot; Glazer, Kara; Goes, Fernando S; Goto, Toyomi; Karberg, Elizabeth; Harrington, Gloria J.; Jakobsen, Petter; Kamali, Masoud; Kelly, Marisa; Leckband, Susan G.; Lohoff, Falk W.; Stautland, Andrea; McCarthy, Michael J.; McInnis, Melvin G.; Mondimore, Francis; Morken, Gunnar; Nurnberger, John I.; Ødegaard, Ketil Joachim; Syrstad, Vigdis Elin Giæver; Ryan, Kelly; Schinagle, Martha; Schøyen, Helle Kristine; Andreassen, Ole; Shaw, Martha; Shilling, Paul D.; Slaney, Claire; Tarwater, Bruce; Calabrese, Joseph R.; Alda, Martin; Nievergelt, Caroline M.; Zandi, Peter P.; Kelsoe, John R. (Journal article; Peer reviewed, 2021)Background Lithium is regarded as a first-line treatment for bipolar disorder (BD), but partial response and non-response commonly occurs. There exists a need to identify lithium non-responders prior to initiating treatment. ... -
Complexity and variability analyses of motor activity distinguish mood states in Bipolar Disorder
Jakobsen, Petter; Stautland, Andrea; Riegler, Michael; Côté-Allard, Ulysse Teller Masao; Sepasdar, Zahra; Nordgreen, Tine; Tørresen, Jim; Fasmer, Ole Bernt; Ødegaard, Ketil Joachim (Journal article; Peer reviewed, 2022)Changes in motor activity are core symptoms of mood episodes in bipolar disorder. The manic state is characterized by increased variance, augmented complexity and irregular circadian rhythmicity when compared to healthy ... -
Diagnosing Schizophrenia from Activity Records using Hidden Markov Model Parameters
Boeker, Matthias; Riegler, Michael; Hammer, Hugo Lewi; Halvorsen, Pål; Fasmer, Ole Bernt; Jakobsen, Petter (Chapter, 2021)The diagnosis of Schizophrenia is mainly based on qualitative characteristics. With the usage of portable devices which measure activity of humans, the diagnosis of Schizophrenia can be enriched through quantitative features. ... -
Diurnal variation of motor activity in adult ADHD patients analyzed with methods from graph theory
Fasmer, Ole Bernt; Fasmer, Erlend Eindride; Mjeldheim, Kristin; Førland, Wenche; Syrstad, Vigdis Elin Giæver; Jakobsen, Petter; Berle, Jan Øystein; Henriksen, Tone Elise Gjøtterud; Sepasdar, Zahra; Hauge, Erik Rønneberg; Ødegaard, Ketil Joachim (Journal article; Peer reviewed, 2020-11)Attention-deficit /hyperactivity disorder (ADHD) is a common neurodevelopmental syndrome characterized by age-inappropriate levels of motor activity, impulsivity and attention. The aim of the present study was to study ... -
Focal adhesion is associated with lithium response in bipolar disorder: evidence from a network-based multi-omics analysis
Niemsiri, Vipavee; Rosenthal, Sara Brin; Nievergelt, Caroline M.; Maihofer, Adam X.; Marchetto, Maria C.; Santos, Renata; Shekhtman, Tatyana; Alliey-Rodriguez, Ney; Anand, Amit; Balaraman, Yokesh; Berrettini, Wade H.; Bertram, Holli; Burdick, Katherine E.; Calabrese, Joseph R.; Calkin, Cynthia V.; Conroy, Carla; Coryell, William H.; DeModena, Anna; Eyler, Lisa T.; Feeder, Scott; Fisher, Carrie; Frazier, Nicole; Frye, Mark A.; Gao, Keming; Garnham, Julie; Gershon, Elliot S.; Goes, Fernando S.; Goto, Toyomi; Harrington, Gloria J.; Jakobsen, Petter; Kamali, Masoud; Kelly, Marisa; Leckband, Susan G.; Lohoff, Falk W.; McCarthy, Michael J.; McInnis, Melvin G.; Craig, David; Millett, Caitlin E.; Mondimore, Francis; Morken, Gunnar; Nurnberger, John I.; Donovan, Claire O’; Ødegaard, Ketil Joachim; Ryan, Kelly; Schinagle, Martha; Shilling, Paul D.; Slaney, Claire; Stapp, Emma K.; Stautland, Andrea; Tarwater, Bruce; Zandi, Peter P.; Alda, Martin; Fisch, Kathleen M.; Gage, Fred H.; Kelsoe, John R. (Journal article; Peer reviewed, 2023)Lithium (Li) is one of the most effective drugs for treating bipolar disorder (BD), however, there is presently no way to predict response to guide treatment. The aim of this study is to identify functional genes and ... -
HYPERAKTIV: An Activity Dataset from Patients with Attention-Deficit/Hyperactivity Disorder (ADHD)
Hicks, Steven; Stautland, Andrea; Fasmer, Ole Bernt; Førland, Wenche; Hammer, Hugo Lewi; Halvorsen, Pål; Mjeldheim, Kristin; Ødegaard, Ketil Joachim; Osnes, Berge; Syrstad, Vigdis Elin Giæver; Riegler, Michael; Jakobsen, Petter (Chapter, 2021)Machine learning research within healthcare frequently lacks the public data needed to be fully reproducible and comparable. Datasets are often restricted due to privacy concerns and legal requirements that come with ... -
Objective assessment of motor activity in a clinical sample of adults with attention-deficit/hyperactivity disorder and/or cyclothymic temperament
Syrstad, Vigdis Elin Giæver; Mjeldheim, Kristin; Førland, Wenche; Jakobsen, Petter; Gjestad, Rolf; Berle, Jan Øystein; Merikangas, Kathleen Ries; Ødegaard, Ketil Joachim; Fasmer, Ole Bernt (Journal article; Peer reviewed, 2022)Background Most research on patterns of motor activity has been conducted on adults with mood disorders, but few studies have investigated comorbid attention-deficit/hyperactivity disorder (ADHD) or temperamental factors ... -
The Pharmacogenomics of Bipolar Disorder study (PGBD): Identification of genes for lithium response in a prospective sample
Ødegaard, Ketil Joachim; Alda, Martin; Anand, Anit; Andreassen, Ole Andreas; Balaraman, Yokesh; Berrettini, Wade H.; Bhattacharjee, Abesh; Brennand, Kristen J.; Burdick, Katherine E.; Calabrese, Joseph R.; Calkin, Cynthia V.; Claasen, Ana; Coryell, William H.; Craig, David; DeModena, Anna; Frye, Mark A.; Gage, Fred H.; Gao, Keming; Garnham, Julie; Gershon, Elliot; Jakobsen, Petter; Leckband, Susan G.; McCarthy, Michael J.; McInnis, Melvin G.; Maihofer, Adam X.; Mertens, Jerome; Morken, Gunnar; Nievergelt, Caroline M.; Nurnberger, John I.; Pham, Son; Schøyen, Helle Kristine; Shekhtman, Tatyana; Shilling, Paul D.; Szelinger, Szabolcs; Tarwater, Bruce; Yao, Jun; Zandi, Peter P.; Kelsoe, John R. (Peer reviewed; Journal article, 2016-05-05)Background: Bipolar disorder is a serious and common psychiatric disorder characterized by manic and depressive mood switches and a relapsing and remitting course. The cornerstone of clinical management is stabilization ... -
Prospective cohort study of early biosignatures of response to lithium in bipolar-I-disorders: overview of the H2020-funded R-LiNK initiative
Scott, Jan; Hidalgo-Mazzei, Diego; Strawbridge, Rebecca; Young, Allan; Resche-Rigon, Matthieu; Etain, Bruno; Andreassen, Ole Andreas; Bauer, Michael; Bennabi, Djamila; Blamire, Andrew M.; Boumezbeur, Fawzi; Brambilla, Paolo; Cattane, Nadia; Cattaneo, Annamaria; Chupin, Marie; Coello, Klara; Cointepas, Yann; Colom, Francesc; Cousins, David A.; Dubertret, Caroline; Duchesnay, Edouard; Ferro, Adele; Garcia-Estela, Aitana; Goikolea, Jose; Grigis, Antoine; Haffen, Emmanuel; Høegh, Margrethe Collier; Jakobsen, Petter; Kalman, Janos L.; Kessing, Lars V.; Klohn-Saghatolislam, Farah; Lagerberg, Trine Vik; Landén, Mikael; Lewitzka, Ute; Lutticke, Ashley; Mazer, Nicolas; Mazzelli, Monica; Mora, Cristina; Muller, Thorsten; Mur-Mila, Estanislao; Ødegaard, Ketil Joachim; Oltedal, Leif; Pålsson, Erik; Papadopoulos Orfanos, Dimitri; Papiol, Sergi; Perez-Sola, Victor; Reif, Andreas; Ritter, Philipp; Rossi, Roberto; Schulze, Thomas; Senner, Fanny; Smith, Fiona E.; Squarcina, Letizia; Steen, Nils Eiel; Thelwall, Pete E.; Varo, Cristina; Vieta, Eduard; Vinberg, Maj; Wessa, Michele; Westlye, Lars Tjelta; Bellivier, Frank (Peer reviewed; Journal article, 2019-09-25)Background Lithium is recommended as a first line treatment for bipolar disorders. However, only 30% of patients show an optimal outcome and variability in lithium response and tolerability is poorly understood. It remains ... -
Reduced heart rate variability during mania in a repeated naturalistic observational study
Stautland, Andrea; Jakobsen, Petter; Fasmer, Ole Bernt; Osnes, Berge; Tørresen, Jim; Nordgreen, Tine; Ødegaard, Ketil Joachim (Journal article; Peer reviewed, 2023)Background: Bipolar disorder (BD) is a chronic recurrent mood disorder associated with autonomic nervous system (ANS) dysfunction, indexed by heart rate variability (HRV). Changes in HRV between mood states are sparsely ...