• Anterior cingulate gamma-aminobutyric acid concentrations and electroconvulsive therapy 

      Erchinger, Vera Jane; Miller, Jeremy; Jones, Thomas; Kessler, Ute; Bustillo, Juan R.; Haavik, Jan; Petrillo, Jonathan; Ziomek, Gregory; Hammar, Åsa; Ødegaard, Ketil Joachim; Calhoun, Vince D.; McClintock, Shawn M.; Ersland, Lars; Oltedal, Leif; Abbott, Christopher (Journal article; Peer reviewed, 2020-09-17)
      Objective The anticonvulsant hypothesis posits that ECT’s mechanism of action is related to enhancement of endogenous anticonvulsant brain mechanisms. Results of prior studies investigating the role of the inhibitory ...
    • Association between gastrointestinal complaints and psychopathology in patients with anorexia nervosa 

      Kessler, Ute; Rekkedal, Guro; Rø, Øyvind; Berentsen, Birgitte; Steinsvik, Elisabeth Kjelsvik; Lied, Gülen Arslan; Danielsen, Yngvild Sørebø (Journal article; Peer reviewed, 2020)
      Objective Gastrointestinal (GI) symptoms appear frequently in patients with anorexia nervosa (AN), but the associations between psychopathological, GI, and eating disorder (ED) symptoms remain unclear. This study aimed ...
    • Brain changes induced by electroconvulsive therapy are broadly distributed 

      Ousdal, Olga Therese; Argyelan, Miklos; Narr, Katherine L.; Abbott, Christopher; Wade, Benjamin; Vandenbulcke, Mathieu; Urretavizcaya, Mikel; Tendolkar, Indira; Takamiya, Akihiro; Stek, Max L.; Soriano-Mas, Carles; Redlich, Ronny; Paulson, Olaf B.; Oudega, Mardien L.; Opel, Nils; Nordanskog, Pia; Kishimoto, Taishiro; Kämpe, Robin; Jørgensen, Anders; Hanson, Lars G.; Hamilton, J. Paul; Espinoza, Randall; Emsell, Louise; van Eijndhoven, Philip; Dols, Annemieke; Dannlowski, Udo; Cardoner, Narcis; Bouckaert, Filip; Anand, Amit; Bartsch, Hauke; Kessler, Ute; Ødegaard, Ketil Joachim; Dale, Anders; Oltedal, Leif (Peer reviewed; Journal article, 2020-03-01)
      Background Electroconvulsive therapy (ECT) is associated with volumetric enlargements of corticolimbic brain regions. However, the pattern of whole-brain structural alterations following ECT remains unresolved. Here, we ...
    • Differences in sleep patterns between patients with anorexia nervosa and healthy controls: a cross-sectional study 

      Kleppe, Malin Mandelid; Kessler, Ute; Rekkedal, Guro Årdal; Skjåkødegård, Hanna Flækøy; Danielsen, Yngvild Sørebø (Journal article; Peer reviewed, 2023)
      Background Sleep difficulties are common in patients with anorexia nervosa (AN), but objective assessments have mostly been performed in hospital and laboratory settings. We aimed to identify differences in sleep patterns ...
    • Effects of ECT in treatment of depression: Study protocol for a prospective neuroradiological study of acute and longitudinal effects on brain structure and function 

      Oltedal, Leif; Kessler, Ute; Ersland, Lars; Grüner, Renate; Andreassen, Ole Andreas; Haavik, Jan; Hoff, Per Ivar; Hammar, Åsa; Dale, Anders Martin; Hugdahl, Kenneth; Ødegaard, Ketil Joachim (Peer reviewed; Journal article, 2015-05-01)
      Background Major depression can be a serious and debilitating condition. For some patients in a treatment resistant depressive episode, electroconvulsive treatment (ECT) is the only treatment that is effective. Although ...
    • Electric field causes volumetric changes in the human brain 

      Argyelan, Miklos; Oltedal, Leif; Deng, Zhi-De; Wade, Benjamin; Bikson, Marom; Joanlanne, Andrea; Sanghani, Sohag; Bartsch, Hauke; Cano, Marta; Dale, Anders M.; Dannlowski, Udo; Dols, Annemieke; Enneking, Verena; Espinoza, Randall; Kessler, Ute; Narr, Katherine L.; Ødegaard, Ketil Joachim; Oudega, Mardien L.; Redlich, Ronny; Stek, Max L.; Takamiya, Akihiro; Emsell, Louise; Bouckaert, Filip; Sienaert, Pascal; Pujol, Jesus; Tendolkar, Indira; van Eijndhoven, Philip; Petrides, Georgios; Malhotra, Anil K.; Abbott, Christopher (Peer reviewed; Journal article, 2019)
      Recent longitudinal neuroimaging studies in patients with electroconvulsive therapy (ECT) suggest local effects of electric stimulation (lateralized) occur in tandem with global seizure activity (generalized). We used ...
    • Electroconvulsive therapy for bipolar disorder depression. Effects on depressive symptoms and cognitive function 

      Kessler, Ute (Doctoral thesis, 2014-11-28)
      Background: Treating the depressive state of bipolar disorder (BD) is challenging. Pharmacological treatments often have poor outcomes. Electroconvulsive therapy (ECT) is generally considered to be the most effective acute ...
    • Electroconvulsive therapy triggers a reversible decrease in brain N-acetylaspartate 

      Erchinger, Vera Jane; Craven, Alexander R.; Ersland, Lars; Oedegaard, Ketil J.; Bartz-Johannessen, Christoffer; Hammar, Åsa Karin; Haavik, Jan; Riemer, Frank; Kessler, Ute; Oltedal, Leif (Journal article; Peer reviewed, 2023)
      Introduction: Based on previous research on electroconvulsive therapy (ECT) we have proposed a model where disruption, potentiation, and rewiring of brain networks occur in sequence and serve as the underlying therapeutic ...
    • Experiences when implementing enhanced cognitive behavioral therapy as a standard treatment for anorexia nervosa in outpatients at a public specialized eating-disorder treatment unit 

      Kessler, Ute; Kleppe, Malin Mandelid; Rekkedal, Guro Årdal; Rø, Øyvind; Danielsen, Yngvild Sørebø (Journal article; Peer reviewed, 2022)
      Background Enhanced cognitive behavioral therapy (CBT-E) is a promising treatment option for outpatients with anorexia nervosa (AN). We aimed to determine the effectiveness of CBT-E as a standard treatment for adult ...
    • Intestinal barrier integrity in anorexia nervosa (a pilot study) 

      Kleppe, Malin M.; Brønstad, Ingeborg; Lied, Gülen Arslan; Danielsen, Yngvild Sørebø; Rekkedal, Guro Årdal; Kessler, Ute (Journal article; Peer reviewed, 2022)
      Objective There is no conclusive evidence for involvement of intestinal barrier alteration in the etiology of anorexia nervosa (AN). The aims of this pilot study were to identify serum markers of intestinal barrier integrity ...
    • Is infertility really associated with higher levels of mental distress in the female population? Results from the North-Trondelag Health Study and the Medical Birth Registry of Norway 

      Biringer, Eva Aaker; Howard, Louise Michele; Kessler, Ute; Stewart, Robert; Mykletun, Arnstein (Peer reviewed; Journal article, 2015)
      Objective: To explore the effect of ever having tried to conceive for more than 12 months on levels of anxiety and depressive symptoms and to investigate if symptom levels of anxiety and depression in infertile women who ...
    • Neurocognitive profiles in treatment-resistant bipolar I and bipolar II disorder depression 

      Kessler, Ute; Schøyen, Helle Kristine; Andreassen, Ole Andreas; Eide, Geir Egil; Hammar, Åsa; Malt, Ulrik F.; Ødegaard, Ketil Joachim; Morken, Gunnar; Sundet, Kjetil; Vaaler, Arne E. (Peer reviewed; Journal article, 2013-04-04)
      Background: The literature on the neuropsychological profiles in Bipolar disorder (BD) depression is sparse. The aims of the study were to assess the neurocognitive profiles in treatment-resistant, acutely admitted BD ...
    • Short and long-term effects of single and multiple sessions of electroconvulsive therapy on brain gray matter volumes 

      Brancati, Giulio Emilio; Brekke, Njål; Bartsch, Hauke; Sørhaug, Ole Johan Evjenth; Ousdal, Olga Therese; Hammar, Åsa Karin; Schuster, Peter Moritz; Ødegaard, Ketil Joachim; Kessler, Ute; Oltedal, Leif (Journal article; Peer reviewed, 2021)
      Background: Electroconvulsive therapy (ECT) has been shown to induce broadly distributed cortical and subcortical volume increases, more prominently in the amygdala and the hippocampus. Structural changes after one ECT ...
    • Structural changes induced by electroconvulsive therapy are associated with clinical outcome 

      Mulders, Peter C. R.; Llera, Alberto; Beckmann, Christian F.; Vandenbulcke, Mathieu; Stek, Max L; Sienaert, Pascal; Redlich, Ronny; Petrides, Georgios; Oudega, Mardien L.; Oltedal, Leif; Ødegaard, Ketil Joachim; Narr, Katherine L; Magnusson, Peter; Kessler, Ute; Jorgensen, Anders; Espinoza, Randall; Enneking, Verena; Emsell, Louise; Dols, Annemieke; Dannlowski, Udo; Bolwig, Tom G; Bartsch, Hauke; Argyelan, Miklos; Anand, Amit; Abbott, Christopher; van Eijndhoven, Philip; Tendolkar, Indira (Journal article; Peer reviewed, 2020)
      Background Electroconvulsive therapy (ECT) is the most effective treatment option for major depressive disorder, so understanding whether its clinical effect relates to structural brain changes is vital for current and ...
    • The study protocol of the Norwegian randomized controlled trial of electroconvulsive therapy in treatment resistant depression in bipolar disorder 

      Kessler, Ute; Vaaler, Arne E.; Schøyen, Helle Kristine; Ødegaard, Ketil Joachim; Bergsholm, Per; Andreassen, Ole Andreas; Malt, Ulrik F.; Morken, Gunnar (Peer reviewed; Journal article, 2010-02-23)
      Background The treatment of depressive phases of bipolar disorder is challenging. The effects of the commonly used antidepressants in bipolar depression are questionable. Electroconvulsive therapy is generally considered ...