Now showing items 1-20 of 57

  • Acute effects of orexigenic antipsychotic drugs on lipid and carbohydrate metabolism in rat 

    Jassim, Goran; Skrede, Silje; Vázquez, María Jesús; Wergedahl, Hege; Vik-Mo, Audun O.; Lunder, Niclas; Diéguez, Carlos; Vidal-Puig, Antonio; Berge, Rolf K.; López, Miguel; Steen, Vidar Martin; Fernø, Johan (Springer, 2011-07-12)
    This study aims to investigate whether orexigenic antipsychotic drugs may induce dyslipidemia and glucose disturbances in female rats through direct perturbation of metabolically active peripheral tissues, independent of ...
    Peer reviewedJournal article
  • Adult attention deficit hyperactivity disorder is associated with asthma 

    Fasmer, Ole Bernt; Halmøy, Anne; Eagan, Tomas Mikal; Ødegaard, Ketil Joachim; Haavik, Jan (BioMed Central, 2011-08-07)
    Background: Attention deficit hyperactivity disorder (ADHD) is increasingly recognized as a common disorder not only in children, but also in the adult population. Similarly, asthma also has a substantial prevalence among ...
    Peer reviewedJournal article
  • Adult attention deficit hyperactivity disorder is associated with migraine headaches 

    Fasmer, Ole Bernt; Halmøy, Anne; Ødegaard, Ketil Joachim; Haavik, Jan (Springer, 2011-03-11)
    Attention deficit hyperactivity disorder (ADHD) is now recognized as a common disorder both in child and adult psychiatry. Adult patients with a diagnosis of ADHD (n = 572) and community controls (n = 675) responded ...
    Peer reviewedJournal article
  • Adults with attention-deficit/hyperactivity disorder. A brain magnetic resonance spectroscopy study 

    Dramsdahl, Margaretha; Ersland, Lars; Plessen, Kerstin von; Haavik, Jan; Hugdahl, Kenneth; Specht, Karsten (Frontiers Research Foundation, 2011-11-23)
    Background: Impaired cognitive control in individuals with attention-deficit/hyperactivity disorder (ADHD) may be related to a prefrontal cortical glutamatergic deficit. We assessed the glutamate level in the left and the ...
    Peer reviewedJournal article
  • Alterations of the retinoblastoma gene in metastatic breast cancer 

    Berge, Elisabet Ognedal; Knappskog, Stian; Lillehaug, Johan; Lønning, Per Eystein (Springer, 2011-01-21)
    Germline mutations affecting the retinoblastoma gene (RB1) predispose to inherited retinoblastomas but also other malignancies, including breast cancer. While somatic RB1 mutations have been detected in different malignancies, ...
    Peer reviewedJournal article
  • Anti-depressive effectiveness of olanzapine, quetiapine, risperidone and ziprasidone: a pragmatic, randomized trial 

    Kjelby, Eirik; Jørgensen, Hugo A.; Kroken, Rune A.; Løberg, Else-Marie; Johnsen, Erik (BioMed Central, 2011-08-31)
    Background: Efficacy studies indicate anti-depressive effects of at least some second generation antipsychotics (SGAs). The Bergen Psychosis Project (BPP) is a 24-month, pragmatic, industry-independent, randomized, ...
    Peer reviewedJournal article
  • Assessing medical students’ attitudes towards learning communication skills – which components of attitudes do we measure? 

    Anvik, Tor; Gude, Tore; Grimstad, Hilde; Bærheim, Anders; Fasmer, Ole Bernt; Hjortdahl, Per; Holen, Are; Risberg, Terje; Vaglum, Per (BioMed Central, 2007-03-30)
    Background. The Communication Skills Attitudes Scale (CSAS) created by Rees, Sheard and Davies and published in 2002 has been a widely used instrument for measuring medical students' attitudes towards learning communication ...
    Journal articlePeer reviewed
  • Associations between tamoxifen, estrogens, and FSH serum levels during steady state tamoxifen treatment of postmenopausal women with breast cancer 

    Gjerde, Jennifer; Geisler, Jürgen; Lundgren, Steinar; Ekse, Dagfinn; Varhaug, Jan Erik; Mellgren, Gunnar; Steen, Vidar Martin; Lien, Ernst Asbjørn (BioMed Central, 2010-06-21)
    Background The cytochrome P450 (CYP) enzymes 2C19, 2D6, and 3A5 are responsible for converting the selective estrogen receptor modulator (SERM), tamoxifen to its active metabolites 4-hydroxy-tamoxifen (4OHtam) and ...
    Peer reviewedJournal article
  • B-type natriuretic peptide and high sensitive C-reactive protein predict 2-year all cause mortality in chest pain patients: a prospective observational study from Salta, Argentina 

    Fuente, Ricardo León de la; Næsgaard, Patrycja A.; Nilsen, Stein Tore; Woie, Leik; Aarsland, Torbjørn; Gallo, Patricio; Grundt, Heidi; Staines, Harry; Nilsen, Dennis W. T. (BioMed Central, 2011-09-29)
    Background: Several mechanisms are involved in the pathophysiology of the Acute Coronary Syndrome (ACS). We have addressed whether B-type natriuretic peptide (BNP) and high-sensitive C-reactive protein (hsCRP) in ...
    Peer reviewedJournal article
  • CDR2 antigen and Yo antibodies 

    Totland, Cecilie; Aarskog, Nina K.; Eichler, Tilo W.; Haugen, Mette; Nøstbakken, Jane K.; Monstad, Sissel E.; Salvesen, Helga B.; Mørk, Sverre; Haukanes, Bjørn Ivar; Vedeler, Christian A. (2011)
    Paraneoplastic cerebellar degeneration (PCD) is often associated with Yo antibodies that are directed against human cerebellar degeneration-related protein 2 (CDR2). Such antibodies may also be found in ovarian cancer ...
    Peer reviewedJournal article
  • Clinical and histological characterization of oral pemphigus lesions in patients with skin diseases: a cross sectional study from Sudan 

    Suliman, Nada M.; Åstrøm, Anne Nordrehaug; Ali, Raouf Wahab; Salman, Hussein; Johannessen, Anne Christine (BioMed Central, 2013-11-21)
    Background: Pemphigus is a rare group of life-threatening mucocutaneous autoimmune blistering diseases. Frequently, oral lesions precede the cutaneous ones. This study aimed to describe clinical and histological features of ...
    Peer reviewedJournal article
  • Complications after intramedullary nailing of femoral fractures in a low-income country. A prospective study of follow-up, HIV infection, and microbial infection rates after IM nailing of 141 femoral fractures at a central hospital in Malawi 

    Young, Sven; Banza, Leonard N.; Hallan, Geir; Beniyasi, Fletcher; Manda, Kumbukani G.; Munthali, Boston S.; Dybvik, Eva Hansen; Engesæter, Lars B.; Havelin, Leif Ivar (Informa Healthcare, 2013-10)
    Background: Some surgeons believe that internal fixation of fractures carries too high a risk of infection in low-income countries (LICs) to merit its use there. However, there have been too few studies from LICs with ...
    Peer reviewedJournal article
  • The cost of multiple sclerosis in Norway 

    Svendsen, Bjørn; Myhr, Kjell-Morten; Nyland, Harald Inge; Aarseth, Jan Harald (Springer, 2010-11-16)
    Health economic aspects have been increasingly important during introduction of new treatments for multiple sclerosis. As a partial response for Norway, a costof- illness study was carried out to estimate the yearly ...
    Peer reviewedJournal article
  • DCLK1 Variants Are Associated across Schizophrenia and Attention Deficit/Hyperactivity Disorder 

    Håvik, Bjarte; Fernandes, Carla P. D.; Christoforou, Andrea; Ersland, Kari Merete; Giddaluru, Sudheer; Cichon, Sven; Steen, Vidar Martin; Hellard, Stéphanie Le; Johansson, Stefan; Bramham, Clive R.; Haavik, Jan (Public Library of Science, 2012-04-23)
    Doublecortin and calmodulin like kinase 1 (DCLK1) is implicated in synaptic plasticity and neurodevelopment. Genetic variants in DCLK1 are associated with cognitive traits, specifically verbal memory and general cognition. ...
    Peer reviewedJournal article
  • Dietary Vitamin D3 Supplements Reduce Demyelination in the Cuprizone Model 

    Wergeland, Stig; Torkildsen, Øivind; Myhr, Kjell-Morten; Aksnes, Lage; Mørk, Sverre; Bø, Lars (Public Library of Science, 2011-10-20)
    Vitamin D is emerging as a probably important environmental risk factor in multiple sclerosis, affecting both susceptibility and disease progression. It is not known to what extent this effect is due to a modulation of ...
    Peer reviewedJournal article
  • The Dynamics and Prognostic Potential of DNA Methylation Changes at Stem Cell Gene Loci in Women's Cancer 

    Zhuang, Joanna; Jones, Allison; Lee, Shih-Han; Ng, Esther; Fiegl, Heidi; Zikan, Michal; Cibula, David; Sargent, Alexandra; Salvesen, Helga B.; Jacobs, Ian J.; Kitchener, Henry C.; Teschendorff, Andrew E.; Widschwendter, Martin (Public Library of Science, 2012-02-09)
    Aberrant DNA methylation is an important cancer hallmark, yet the dynamics of DNA methylation changes in human carcinogenesis remain largely unexplored. Moreover, the role of DNA methylation for prediction of clinical ...
    Peer reviewedJournal article
  • Effectiveness of second generation antipsychotics: A systematic review of randomized trials 

    Johnsen, Erik; Jørgensen, Hugo A. (BioMed Central, 2008-04-25)
    Background Systematic reviews based on efficacy trials are inconclusive about which second generation antipsychotic drug (SGA) should be preferred in normal clinical practice, and studies with longer duration and more ...
    Journal articlePeer reviewed
  • Evaluation of four novel genetic variants affecting hemoglobin A1c levels in a population-based type 2 diabetes cohort (the HUNT2 study) 

    Hertel, Jens Kristoffer; Johansson, Stefan; Ræder, Helge; Platou, Carl G. P.; Midthjell, Kristian; Hveem, Kristian; Molven, Anders; Njølstad, Pål Rasmus (BioMed Central, 2011-02-04)
    Background: Chronic hyperglycemia confers increased risk for long-term diabetes-associated complications and repeated hemoglobin A1c (HbA1c) measures are a widely used marker for glycemic control in diabetes treatment and ...
    Peer reviewedJournal article
  • Exercise-induced laryngeal obstruction: natural history and effect of surgical treatment 

    Maat, Robert Christiaan; Hilland, Magnus; Røksund, Ola Drange; Halvorsen, Thomas; Olofsson, Jan; Aarstad, Hans Jørgen; Heimdal, John-Helge (Springer, 2011-06-05)
    The current follow-up study concerning the supraglottic type of exercise-induced laryngeal obstruction (EILO) was performed to reveal the natural history of supraglottic EILO and compare the symptoms, as well as the ...
    Peer reviewedJournal article
  • Exome Sequencing and Genetic Testing for MODY 

    Johansson, Stefan; Irgens, Henrik; Chudasama, Kishan K.; Molnes, Janne; Aerts, Jan; Knappskog, Per; Njølstad, Pål Rasmus; Roque, Francisco S.; Jonassen, Inge; Molven, Anders (Public Library of Science, 2012-05-25)
    Context: Genetic testing for monogenic diabetes is important for patient care. Given the extensive genetic and clinical heterogeneity of diabetes, exome sequencing might provide additional diagnostic potential when standard ...
    Peer reviewedJournal article