Now showing items 11-20 of 283
Survival in Norwegian BRCA1 mutation carriers with breast cancer
(BioMed Central, 2009-04-14)
Several studies of survival in women with BRCA1 mutations have shown either reduced survival or no difference compared to controls. Programmes for early detection and treatment of inherited breast cancer, have failed to ...
Functional level after Traumatic Brain Injury
(The University of Bergen, 2012-02-03)
Objectives: The objectives of the thesis were to describe the functional level (papers I and II) and self awareness of functional deficits (paper III) after moderate and severe Traumatic Brain Injury (TBI), and to ...
Economic aspects of Parkinson’s disease
(The University of Bergen, 2009-11-13)
Background: Next to Alzheimer’s disease, Parkinson’s disease (PD) is the second most neurodegenerative disease. As the population structure in the industrialized and industrializing countries is changing, an increasing ...
Neuroborreliosis in children: Epidemiological and clinical aspects
(The University of Bergen, 2012-06-08)
Background: Lyme borreliosis (LB) caused by the bacteria Borrelia burgdorferi sensu lato (Bbsl) is the most common tick transmitted infection in Europe. LB is a multi systemic infection that develops when the bacteria ...
Paraneoplastic CDR2 and CDR2L antibodies affect Purkinje cell calcium homeostasis
Paraneoplastic cerebellar degeneration (PCD) is characterized by loss of Purkinje cells (PCs) associated with progressive pancerebellar dysfunction in the presence of onconeural Yo antibodies. These antibodies recognize ...
Computer Navigation in Total Knee Replacement Surgery. Effect on Outcome
(The University of Bergen, 2013-11-29)
Background: In total knee replacement surgery (TKR), the surgeon aims to align the implant according to the mechanical axis of the limb. Among knee surgeons the dominating belief is that good alignment reduces wear and ...
Developing a novel femoral stem in hip arthroplasty. An innovation process using a weight-bearing animal model
(The University of Bergen, 2015-08-20)
Introduction: To address the growing incidence of hip replacement revision, this project aimed to find a stem that would fulfil three criteria. First, solid osteointegration and long survival of the implant. Second, ...
Mutations and gene amplifications in Endometrial Carcinomas. “Clinical characteristics and potential targets for therapy related to KRAS, MYC, ATAD2, PIK3CA and FGFR2 alterations”
(The University of Bergen, 2013-09-20)
Background: Incidence of endometrial cancer is increasing in industrialised countries. Despite early diagnosis and generally good prognosis, around one fourth of cases follow an aggressive path with few effective treatment ...
Transfusion requirements in septic shock (TRISS) trial - comparing the effects and safety of liberal versus restrictive red blood cell transfusion in septic shock patients in the ICU: protocol for a randomised controlled trial
(BioMed Central, 2013-05-23)
Background: Transfusion of red blood cells (RBC) is recommended in septic shock and the majority of these patients receive RBC transfusion in the intensive care unit (ICU). However, benefit and harm of RBCs have not ...
Colorectal Cancer in Norway. National Treatment Guidelines and Outcomes
(The University of Bergen, 2013-04-05)