Recent Submissions

  • Dietary RNA (s. Cerevisiae) stimulated cytokine secretion in human immune cells: involvement of p38 MAPK, and co-stimulation with LPS or PHA 

    Nuland, Ole Petter (The University of Bergen, 2009-07-01)
    Dietary nucleotides and nucleic acids are known to affect immune functions in animals and humans, both in vitro and in vivo. In this thesis I wanted to investigate the effect of dietary RNA from baker’s yeast on cytokine ...
    Master thesis
  • Circulating Vitamin D in relation to cancer incidence and survival of the head and neck and oesophagus in the EPIC cohort 

    Fanidi, Anouar; Muller, David C.; Midttun, Øivind; Ueland, Per Magne; Vollset, Stein Emil; Relton, Caroline; Vineis, Paolo; Weiderpass, Elisabete; Skeie, Guri; Brustad, Magritt; Palli, Domenico; Tumino, Rosario; Grioni, Sara; Sacerdote, Carlotta; Bueno-de-Mesquita, H. Bas; Peeters, Petra H.; Boutron-Ruault, Marie-Christine; Kvaskoff, Marina; Cadeau, Claire; Huerta, José María; Sánchez, María-José; Agudo, Antonio; Lasheras, Cristina; Quirós, J. Ramón; Chamosa, Saioa; Riboli, Elio; Travis, Ruth C; Ward, Heather; Murphy, Neil; Khaw, Kay-Tee; Trichopoulou, Antonia; Lagiou, Pagona; Papatesta, Eleni-Maria; Boeing, Heiner; Kühn, Tilman; Katzke, Verena; Steffen, Annika; Johansson, Anders; Brennan, Paul; Johansson, Mattias (Nature Publishing Group, 2016-11-04)
    Experimental and epidemiological data suggest that vitamin D play a role in pathogenesis and progression of cancer, but prospective data on head and neck cancer (HNC) and oesophagus cancer are limited. The European Prospective ...
    Journal article
  • Motor development related to duration of exclusive breastfeeding, B vitamin status and B12 supplementation in infants with a birth weight between 2000-3000 g, results from a randomized intervention trial 

    Torsvik, Ingrid Kristin; Ueland, Per Magne; Markestad, Trond; Midttun, Øivind; Monsen, Anne-Lise Bjørke (BioMed Central, 2015-12-18)
    Background: Exclusive breastfeeding for 6 months is assumed to ensure adequate micronutrients for term infants. Our objective was to investigate the effects of prolonged breastfeeding on B vitamin status and neurodevelopment ...
    Journal article
  • Seafarers' wives and intermittent husbands - social and psychological impact of a subgroup of Norwegian seafarers' work schedule on their families 

    Ulven, Arne Johan; Omdal, Knut Arve; Herløv-Nielsen, Henrik; Irgens, Ågot; Dahl, Eilif (Via Medica, 2007)
    Objective – To examine the psycho-social impact of work schedules (absence from home) on the families of a subgroup of Norwegian seafarers as reported by their wives (sea wives). Their husbands worked 4-6 weeks on ...
    Journal article
  • Risk of Misclassification of decompression sickness 

    Sundal, Endre; Grønning, Marit; Troland, Kari; Irgens, Ågot; Aanderud, Leif; Thorsen, Einar (Via Medica, 2011)
    Decompression sickness (DCS) is classified on the basis of which organ system is affected, and neurological DCS is considered more severe than DCS in joints and skin with respect to response to recompression treatment and ...
    Journal article
  • Seafarer with solitary, well-functioning kidney - fit for service at sea without restrictions? 

    Schepers, Bernd-Fred; Dahl, Eilif (Via Medica, 2010)
    A 20-year-old, healthy man, who four years earlier had lost a kidney in a skiing accident, applied for a medical fitness certificate for service on board German flag vessels. Under reference to national and international ...
    Journal article
  • A genome-wide association study in chronic obstructive pulmonary disease (COPD): Identification of two major susceptibility loci 

    Pillai, Sreekumar G.; Ge, Dongliang; Zhu, Guohua; Kong, Xiangyang; Shianna, Kevin V.; Need, Anna C.; Feng, Sheng; Hersh, Craig P.; Bakke, Per S.; Gulsvik, Amund; Ruppert, Andreas; Carlsen, Karin Cecilie Lødrup; Roses, Allen; Anderson, Wayne; Rennard, Stephen I.; Lomas, David A.; Silverman, Edwin K.; Goldstein, David B. (PLoS, 2009-03-20)
    There is considerable variability in the susceptibility of smokers to develop chronic obstructive pulmonary disease (COPD). The only known genetic risk factor is severe deficiency of α1-antitrypsin, which is present in ...
    Journal article
  • The Role of Long-Chained Marine N-3 Polyunsaturated Fatty Acids in Cardiovascular Disease 

    Aarsetøy, Hildegunn; Grundt, Heidi; Nygård, Ottar; Nilsen, Dennis W.T. (Hindawi, 2012)
    This paper reviews the current evidence regarding long-chained marine omega-3 polyunsaturated fatty acids (PUFAs) and cardiovascular disease (CVD), their possible mechanisms of action, and results of clinical trials. Also, ...
    Journal article
  • Vitamin D predicts all-cause and cardiac mortality in females with suspected acute coronary syndrome: a comparison with brain natriuretic peptide and high-sensitivity C-reactive protein 

    Næsgaard, Patrycja; Fuente, Ricardo León de la; Nilsen, Stein Tore; Woie, Leik; Årsland, Torbjørn; Staines, Harry; Nilsen, Dennis W.T. (Hindawi, 2013)
    Vitamin D may not only reflect disease but may also serve as a prognostic indicator. Our aim was to assess the gender-specific utility of vitamin D measured as 25-hydroxy-vitamin D [25(OH)D] to predict all-cause and cardiac ...
    Journal article
  • A Blended Learning Course Design in Clinical Pharmacology for Post-graduate Dental Students 

    Rosenbaum, Paul-Erik Lillholm; Mikalsen, Øyvind; Lygre, Henning; Solheim, Einar; Schjøtt, Jan (Bentham Open, 2012)
    Postgraduate courses in clinical pharmacology are important for dentists to be updated on drug therapy and information related to their clinical practice, as well as knowledge of relevant adverse effects and interactions. ...
    Journal article
  • A novel, single-amplification PCR targeting mitochondrial genome highly sensitive and specific in diagnosing malaria among returned travellers in Bergen, Norway 

    Haanshuus, Christel Gill; Mohn, Stein Christian; Mørch, Kristine; Langeland, Nina; Blomberg, Bjørn; Hanevik, Kurt (BioMed Central, 2013-01-22)
    Background: Nested PCR is a commonly used technique in diagnosis of malaria owing to its high sensitivity and specificity. However, it is time-consuming, open to considerable risk of contamination and has low cost-efficiency. ...
    Journal article
  • Densities of rectal peptide YY and somatostatin cells as biomarkers for the diagnosis of irritable bowel syndrome 

    El-Salhy, Magdy; Hatlebakk, Jan G; Gilja, Odd Helge; Hausken, Trygve (Elsevier, 2015-03-09)
    Irritable bowel syndrome (IBS) is a common chronic disorder. IBS diagnosis is a diagnosis of exclusion since there are no blood tests, radiological or endoscopic examinations for this disorder. Although several attempts ...
    Journal article
  • Autoimmunity and viral immunity in Addison’s disease 

    Waade Edvardsen, Kine Susann (The University of Bergen, 2015-11-27)
    Autoimmune Addison’s disease (AAD) is caused by an immunological destruction of the steroid producing cells of the adrenal cortex. Both genetic and environmental factors are involved in disease development, and while ...
    Doctoral thesis
  • Diet in irritable bowel syndrome 

    El-Salhy, Magdy; Gundersen, Doris Irene (BioMed Central Ltd, 2015-04-14)
    Irritable bowel syndrome (IBS) is a common chronic gastrointestinal disorder that is characterized by intermittent abdominal pain/discomfort, altered bowel habits and abdominal bloating/distension. This review aimed at ...
    Journal article
  • Longterm follow-up in European respiratory health studies - patterns and implications 

    Johannessen, Ane; Verlato, Guiseppe; Benediktsdottir, Bryndis; Forsberg, Bertil; Franklin, Karl; Gíslason, Thorainn; Holm, Mathias; Janson, Christer; Jögi, Rain; Lindberg, Eva; Macsali, Ferenc; Omenaas, Ernst; Gomez Real, Francisco; Saure, Eirunn Waatevik; Schlünssen, Vivi; Sigsgaard, Torben; Skorge, Trude Duelien; Svanes, Cecilie; Torén, Kjell; Waatevik, Marie Johanne; Nilsen, Roy Miodini; de Marco, Roberto (BioMed Central, 2014-04-16)
    Background: Selection bias is a systematic error in epidemiologic studies that may seriously distort true measures of associations between exposure and disease. Observational studies are highly susceptible to selection ...
    Journal article
  • Limited clinical efficacy of azacitidine in transfusion-dependent, growth factor-resistant, low- and Int-1-risk MDS: Results from the nordic NMDSG08A phase II trial 

    Tobiasson, Magnus; Dybedal, Ingunn; Holm, Mette Skov; Karimi, Mohsen; Brandefors, Lena; Garelius, Hege; Grövdal, Michael; Høgh-Dufva, Inge; Grønbæk, Kirsten; Jansson, Monika; Marcher, Vlaus Werenberg; Nilsson, Lars Håkan; Kittang, Astrid Marta Olsnes; Porwit, Anna; Saft, Leonie; Möllgård, Lars; Hellström-Lindberg, Eva (Nature Publishing Group, 2014)
    This prospective phase II study evaluated the efficacy of azacitidine (Aza)+erythropoietin (Epo) in transfusion-dependent patients with lower-risk myelodysplastic syndrome (MDS). Patients ineligible for or refractory to ...
    Journal article
  • Abundant Genetic Overlap between Blood Lipids and Immune-Mediated Diseases Indicates Shared Molecular Genetic Mechanisms 

    Andreassen, Ole Andreas; Desikan, Rahul S.; Wang, Yunpeng; Thompson, Wesley K.; Schork, Andrew J.; Zuber, Verena; Doncheva, Nadezhda T.; Ellinghaus, E.va; Mattingsdal, Morten; Franke, Andre; Lie, Benedicte. A.; Mills, Ian Geoffrey; Aukrust, Pål; McEvoy, Linda K.; Djurovic, Srdjan; Karlsen, Tom H.; Dale, Anders M. (PLoS, 2015-04-08)
    Epidemiological studies suggest a relationship between blood lipids and immune-mediated diseases, but the nature of these associations is not well understood. We used genome-wide association studies (GWAS) to investigate ...
    Journal article
  • Prognostic impact of vitamin B6 metabolism in lung cancer 

    Galluzzi, Lorenzo; Vitale, Ilio; Senovilla, Laura; Olaussen, Ken André; Pinna, Guillaume; Eisenberg, Tobias; Goubar, Aïcha; Martins, Isabelle; Michels, Judith; Kratassiouk, Guerorgui; Carmona-Gutierrez, Didac; Scoazec, Marie; Vacchelli, Erika; Schlemmer, Frederic; Kepp, Oliver; Shen, Sheshi; Tailler, Maximilien; Niso-Santano, Mireia; Morselli, Eugenia; Criollo, Alfredo; Adjemian, Sandy; Jemaa, Mohamed; Chaba, Kariman; Pailleret, Claire; Michaud, Mickaël; Pietrocola, Federico; Tajeddine, Nicolas; Rouge, Thibault de La Motte; Araujo, Natalia; Morozova, Nadya; Robert, Thomas; Ripoche, Hugues; Commo, Frederic; Besse, Benjamin; Validire, Pierre; Fouret, Pierre; Robin, Angélique; Dorvault, Nicolas; Girard, Philippe; Gouy, Sébastien; Pautier, Patricia; Jägemann, Nora; Nickel, Ann-Christin; Marsili, Sabrina; Paccard, Caroline; Servant, Nicolas; Hupé, Philippe; Behrens, Carmen; Behnam-Motlagh, Paviz; Kohno, Kimitoshi; Cremer, Isabelle; Damotte, Diane; Alifano, Marco; Midttun, Øivind; Ueland, Per Magne; Lazar, Vladimir; Dessen, Philippe; Zischka, Hans; Chatelut, Etienne; Castedo, Maria; Madeo, Frank; Barillot, Emmanuel; Thomale, Jürgen; Wistuba, Ignacio Ivan; Sautes-Fridman, Catherine; Zitvogel, Laurence; Soria, Jean-Charles; Harel-Bellan, Annick; Kroemer, Guido (Elsevier, 2012-08-30)
    Patients with non-small cell lung cancer (NSCLC) are routinely treated with cytotoxic agents such as cisplatin. Through a genome-wide siRNA-based screen, we identified vitamin B6 metabolism as a central regulator of cisplatin ...
    Journal article
  • A salmon peptide diet alleviates experimental colitis as compared with fish oil 

    Grimstad, Tore; Bjørndal, Bodil; Cacabelos, Daniel; Aasprong, Ole Gunnar; Omdal, Roald; Svardal, Asbjørn M.; Bohov, Pavol; Pamplona, Reinald; Portero-Otin, Manuel; Berge, Rolf Kristian; Hausken, Trygve (Cambridge University Press, 2013-01-10)
    Fish oil (FO) has been shown to have anti-inflammatory properties in animal models of inflammatory bowel disease, but how fish peptides (FP) influence intestinal inflammation has been less studied. Male Wistar rats, divided ...
    Journal article

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