Now showing items 1-10 of 220
Bioactive fatty acids and coronary heart disease. Mechanisms and clinical effects of dietary fatty acids
(The University of Bergen, 2013-06-26)
Background: A high intake of omega-3 (n-3) long-chain polyunsaturated fatty acids (LCPUFAs), which are potential peroxisome proliferator-activated receptor (PPAR) agonists, has been associated with proposed favourable ...
Do gastrointestinal complaints increase the risk for subsequent medically certified long-term sickness absence? The HUSK study
(BioMed Central, 2011-07-29)
Background: Gastrointestinal complaints are very common in the general population and very often co-occur with common mental disorders. We aimed to study the prospective impact of gastrointestinal complaints on long ...
Effect of the MDM2 promoter polymorphisms SNP309T>G and SNP285G>C on the risk of ovarian cancer in BRCA1 mutation carriers
(BioMed Central, 2012-10-05)
Background: While BRCA mutation carriers possess a 20-40% lifetime risk of developing ovarian cancer, knowledge about genetic modifying factors influencing the phenotypic expression remains obscure. We explored the ...
Betaine as a determinant of postmethionine load total plasma homocysteine before and after B-Vitamin supplementation
Objective—Betaine is a substrate in the betaine– homocysteine methyltransferase reaction, converting homocysteine to methionine. There are only sparse data on plasma betaine as a determinant of the plasma total homocysteine ...
Lung cancer in Agder counties in Southern Norway - results from a three year unselected inclusion of patients with newly diagnosed lung cancer
(The University of Bergen, 2009-11-10)
Genome-wide copy number variation (CNV) in patients with autoimmune Addison’s disease
(BioMed Central, 2011-08-18)
Background: Addison’s disease (AD) is caused by an autoimmune destruction of the adrenal cortex. The pathogenesis is multi-factorial, involving genetic components and hitherto unknown environmental factors. The aim of ...
Studies on homocysteine-lowering B-vitamin therapy in patients with coronary artery diseas : sub-studies from the Western Norway B-vitamin intervention trial (WENBIT)
(The University of Bergen, 2008-06-06)
Background: A high plasma level of total homocysteine (tHcy) is a risk factor for cardiovascular disease, and is related to important components of atherosclerosis such as inflammation and endothelial dysfunction. Objectives: ...
Homocysteine-lowering clinical trials in Norway. Cardiovascular and cancer outcomes in the Western Norway B Vitamin Intervention Trial and the Norwegian Vitamin Trial
(The University of Bergen, 2010-09-17)
Introduction: Observational studies have reported associations between levels of the amino acid homocysteine in the circulation and risk of cardiovascular disease. Oral administration of the synthetic B vitamins folic ...