Now showing items 111-120 of 220
Switch from stress response to homeobox transcription factors in Adipose tissue after profound fat loss
(Public Library of Science, 2010-06-09)
Background In obesity, impaired adipose tissue function may promote secondary disease through ectopic lipid accumulation and excess release of adipokines, resulting in systemic low-grade inflammation, insulin resistance ...
Cost effectiveness of adding budesonide/formoterol to tiotropium in COPD in four Nordic countries
Objective: Assess the cost effectiveness of budesonide/formoterol (BUD/FORM) Turbuhaler®+tiotropium (TIO) HandiHaler® vs. placebo (PBO)+TIO in patients with chronic obstructive pulmonary disease (COPD) eligible for inhaled ...
Cross-Species Functional Genomic Analysis Identifies Resistance Genes of the Histone Deacetylase Inhibitor Valproic Acid
(Public Library of Science, 2012-11-14)
The mechanisms of successful epigenetic reprogramming in cancer are not well characterized as they involve coordinated removal of repressive marks and deposition of activating marks by a large number of histone and DNA ...
N-terminal pro-B-type natriuretic peptide level at longterm follow-up after atrial fibrillation ablation: A marker of reverse atrial remodeling and successful ablation
Aims: We investigated the relationship between arrhythmia burden, left atrial volume (LAV) and N-terminal pro-B-type natriuretic peptide (NT-pro-BNP) at baseline and after long-term follow-up of atrial fibrillation (AF) ...
Anti-Interferon Autoantibodies in Autoimmune Polyendocrinopathy Syndrome Type 1
(Public Library of Science, 2006-06-13)
Background The autoimmune regulator (AIRE) gene influences thymic self-tolerance induction. In autoimmune polyendocrinopathy syndrome type 1 (APS1; OMIM 240300), recessive AIRE mutations lead to autoimmunity targetting ...
Dendritic cell populations in patients with self-reported food hypersensitivity
(BMJ Publishing Group, 2010)
Multilocus analysis of SNP and metabolic data within a given pathway
(BioMed Central, 2006-01-13)
Background: Complex traits, which are under the influence of multiple and possibly interacting genes, have become a subject of new statistical methodological research. One of the greatest challenges facing human geneticists ...
Densities of rectal peptide YY and somatostatin cells as biomarkers for the diagnosis of irritable bowel syndrome
Irritable bowel syndrome (IBS) is a common chronic disorder. IBS diagnosis is a diagnosis of exclusion since there are no blood tests, radiological or endoscopic examinations for this disorder. Although several attempts ...
Contrast stress echocardiography in hypertensive heart disease
(BioMed Central, 2011-11-18)
Hypertension is associated with atherosclerosis and cardiac and vascular structural and functional changes. Myocardial ischemia may arise in hypertension independent of coronary artery disease through an interaction between ...
Krill oil attenuates left ventricular dilatation after myocardial infarction in rats
(BioMed Central, 2011-12-29)
Background: In the western world, heart failure (HF) is one of the most important causes of cardiovascular mortality. Supplement with n-3 polyunsaturated fatty acids (PUFA) has been shown to improve cardiac function in HF ...