Now showing items 21-30 of 225
Long-term treatment with the pan-PPAR agonist tetradecylthioacetic acid or fish oil is associated with increased cardiac content of n-3 fatty acids in rat
(BioMed Central, 2012-06-27)
Background: Excess peroxisome proliferator-activated receptor (PPAR) stimulation has been associated with detrimental health effects including impaired myocardial function. Recently, supplementation with n-3 polyunsaturated ...
Autoimmune polyendocrine syndrome type I. Novel diagnostic assays and immune regulation
(The University of Bergen, 2012-02-10)
Autoimmune polyendocrine syndrome type I (APS-I) is a rare, monogenetic recessively inherited disease caused by mutations in the autoimmune regulator (AIRE) gene. The patients display different endocrine and ectodermal ...
Genetic biomarkers as prognostic and predictive factors in metastatic malignant melanoma
(The University of Bergen, 2010-10-26)
Malignant melanoma is one of the most chemoresistant malignancies in man. Although effort is put into developing new drugs to treat metastatic melanoma, still dacarbazine, an alkylating agent approved in 1975 for therapeutic ...
Calprotectin (S100A8/A9) and S100A12 in inflammatory arthritis : clinical and epidemiological studies of rheumatoid and psoriatic arthritis
(The University of Bergen, 2007-12-14)
Rheumatoid- and psoriatic arthritis (RA and PsA) are the two most prevalent inflammatory joint diseases in Caucasian. Different biomarkers in peripheral blood may contribute in the diagnostic and prognostic process, as ...
Assessment of cobalamin status in experimental and clinical studies by intracellular and extracellular markers of vitamin function
(The University of Bergen, 2006-02-02)
The European Cardiac Resynchronization Therapy (CRT) Survey
(The University of Bergen, 2011-10-20)
Aims: The European Cardiac Resynchronization Therapy (CRT) Survey was a joint initiative taken by the Heart Failure (HFA) and the European Heart Rhythm (EHRA) Associations of the European Society of Cardiology (ESC) ...
Ultrasound Strain Rate Imaging in Functional Dyspepsia : in-vitro and clinical evaluation
(The University of Bergen, 2008-06-20)
Functional dyspepsia (FD) is a chronic condition that is characterized by abdominal pain or discomfort, nausea, vomiting, early satiation and abdominal fullness. The Rome III classification of functional gastrointestinal ...
Association between long-term neuro-toxicities in testicular cancer survivors and polymorphisms in glutathione-s-transferase-P1 and -M1, a retrospective cross sectional study
(BioMed Central, 2007-12-27)
Background: To assess the impact of polymorphisms in Glutathione S-transferase (GST) -P1, - M1, and -T1 on self-reported chemotherapy-induced long-term toxicities in testicular cancer survivors (TCSs). Methods: A total ...
Update on primary sclerosing cholangitis
Primary sclerosing cholangitis (PSC) remains one of the most challenging conditions of clinical hepatology. There has been a steady growth in research to overcome this fact and the present review aims at summarizing the ...