Blar i Bergen Open Research Archive på forfatter "McCann, Adrian"
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Stable isotope ratios of nitrogen and carbon as biomarkers of a vegan diet
Dierkes, Jutta; Dietrich, Stefan; Abraham, Klaus; Monien, Bernhard H.; McCann, Adrian; Borgå, Katrine; Weikert, Cornelia (Journal article; Peer reviewed, 2022)Purpose Dietary biomarkers can potentially overcome the limitations of self-reported dietary data. While in ecology and archaeology, stable isotope ratios of carbon and nitrogen are widely used as biomarkers, this is not ... -
Time-Resolved Concentrations of Serum Amino Acids, One-carbon Metabolites, and B-vitamin Biomarkers during the Postprandial and Fasting State: The Postprandial Metabolism in Healthy Young Adults (PoMet) study
Anfinsen, Åslaug Matre; Johannesen, Christina Osland; Myklebust, Vilde H.; Rosendahl-Riise, Hanne; McCann, Adrian; Nygård, Ottar Kjell; Dierkes, Jutta; Lysne, Vegard (Journal article; Peer reviewed, 2023)Metabolomics has been utilised in epidemiological studies to investigate biomarkers of nutritional status and metabolism in relation to non-communicable diseases. However, little is known about the effect of prandial status ... -
Tryptophan catabolites as metabolic markers of vitamin B-6 status evaluated in cohorts of healthy adults and cardiovascular patients
Ulvik, Arve; Midttun, Øivind; McCann, Adrian; Meyer, Klaus; Tell, Grethe S.; Nygård, Ottar; Ueland, Per Magne (Journal article; Peer reviewed, 2020)Background Vitamin B-6 status is routinely measured as pyridoxal 5′-phosphate (PLP) in plasma. Low concentrations of PLP are associated with rheumatic, cardiovascular, and neoplastic diseases. We have previously shown ... -
Urine and plasma concentrations of amino acids and plasma vitamin status differ, and are differently affected by salmon intake, in obese Zucker fa/fa rats with impaired kidney function and in Long-Evans rats with healthy kidneys
Drotningsvik, Aslaug; Midttun, Øivind; Vikøren, Linn Anja Slåke; McCann, Adrian; Ueland, Per Magne; Mellgren, Gunnar; Gudbrandsen, Oddrun Anita (Peer reviewed; Journal article, 2019)Kidney function affects amino acid metabolism and vitamin status. The aims of the present study were to investigate urine and plasma concentrations of amino acids as well as plasma vitamin status in rats with impaired renal ... -
Using metabolic profiling and gene expression analyses to explore molecular effects of replacing saturated fat with polyunsaturated fat-a randomized controlled dietary intervention study
Ulven, Stine Marie; Christensen, Jacob J.; Nygård, Ottar; Svardal, Asbjørn M.; Leder, Lena; Ottestad, Inger; Lysne, Vegard; Laupsa-Borge, Johnny; Ueland, Per Magne; Midttun, Øivind; Meyer, Klaus; McCann, Adrian; Andersen, Lene Frost; Holven, Kirsten Bjørklund (Peer reviewed; Journal article, 2019-04-26)Background: Replacing dietary saturated fatty acids (SFAs) with polyunsaturated fatty acids (PUFA) reduces the plasma low-density lipoprotein (LDL) cholesterol and subsequently the risk of cardiovascular disease. However, ... -
Vitamin B12 and folate status in pregnant females and their infants in Norway: Secondary analysis from the Mommy´s Food Study
Bjørkevoll, Sol Maja Graasvold; Konijnenberg, Carolien; Kvestad, Ingrid Hafting; McCann, Adrian; Ueland, Per Magne; Næss, Synnøve; Dahl, Lisbeth; Kjellevold, Marian; Strand, Tor Arne; Markhus, Maria Wik (Journal article; Peer reviewed, 2023)Background: Vitamin B12 and folate are essential micronutrients important for normal infant growth and development. Objectives: The aims were to describe vitamin B12 and folate status in pregnant females and their infants ... -
Vitamin B12 status in infancy and the effect of a vitamin B12 injection in infants with subclinical vitamin B12 deficiency: study protocol for a register-based randomised controlled trial
Bakken, Kjersti Sletten; Kvestad, Ingrid; Bjørkevoll, Sol Maja Graasvold; Solvik, Beate Stokke; Kaldenbach, Siri; McCann, Adrian; Holten-Andersen, Mads Nikolaj; Ersvær, Elisabeth; Konijnenberg, Carolien; Strand, Tor Arne (Journal article; Peer reviewed, 2023)Introduction: Vitamin B12 (cobalamin) is crucial for optimal child development and growth, yet deficiency is common worldwide. The aim of this study is twofold; (1) to describe vitamin B12 status and the status of other ... -
Within-person reproducibility of proteoforms related to inflammation and renal dysfunction
Gao, Jie; McCann, Adrian; Laupsa-Borge, Johnny; Nygård, Ottar Kjell; Ueland, Per Magne; Meyer, Klaus (Journal article; Peer reviewed, 2022)Protein biomarkers and microheterogeneity have attracted increasing attention in epidemiological and clinical research. Knowledge of within-person reproducibility over time is paramount to determine whether a single ...