Blar i Bergen Open Research Archive på forfatter "Gudbrandsen, Oddrun Anita"
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Absence of the proteoglycan decorin reduces glucose tolerance in overfed male mice
Svärd, Jessica; Røst, Therese Halvorsen; Sommervoll, Camilla Elise Nergård; Haugen, Christine; Gudbrandsen, Oddrun Anita; Christensen, Anne Elisabeth; Rødahl, Eyvind; Fernø, Johan; Dankel, Simon N; Sagen, Jørn V.; Mellgren, Gunnar (Peer reviewed; Journal article, 2019)Studies have implicated the extracellular matrix (ECM) of adipose tissue in insulin resistance. The proteoglycan decorin, a component of ECM, has been associated with glucose tolerance, but possible causal effects on ... -
Automated spectrophotometric bicarbonate analysis in duodenal juice compared to the back titration method
Erchinger, Friedemann Georg; Engjom, Trond; Gudbrandsen, Oddrun Anita; Tjora, Erling; Gilja, Odd Helge; Dimcevski, Georg Gjorgji (Peer reviewed; Journal article, 2016-02-03)Objectives We have recently evaluated a short endoscopic secretin test for exocrine pancreatic function. Bicarbonate concentration in duodenal juice is an important parameter in this test. Measurement of bicarbonate by ... -
Baked cod consumption delayed the development of kidney and liver dysfunction and affected plasma amino acid concentrations, but did not affect blood pressure, blood glucose or liver triacylglycerol concentrations in obese fa/fa Zucker rats.
Vikøren, Linn A.; Drotningsvik, Aslaug; Midttun, Øivind; McCann, Adrian; Bergseth, Marthe Tønder; Austgulen, Maren H.; Mellgren, Gunnar; Ueland, Per Magne; Gudbrandsen, Oddrun Anita (Journal article; Peer reviewed, 2021)Obesity is associated with changes in amino acid metabolism, and studies show that ingestion of fish proteins influence amino acid composition in plasma and urine, in addition to affecting risk factors for metabolic syndrome. ... -
Cod protein powder lowered serum nonesterified fatty acids and increased total bile acid concentrations in healthy, lean, physically active adults: A randomized double-blind study
Vildmyren, Iselin; Halstensen, Alfred; Oterhals, Åge; Gudbrandsen, Oddrun Anita (Peer reviewed; Journal article, 2019-03-11)Background: Fish fillet consumption is associated with beneficial health effects; however, little is known about whether consuming other parts of the fish such as head, backbone, skin, cut-offs, and entrails (collectively ... -
Cod Residual Protein Prevented Blood Pressure Increase in Zucker fa/fa Rats, Possibly by Inhibiting Activities of Angiotensin-Converting Enzyme and Renin
Vildmyren, Iselin Thowsen; Drotningsvik, Aslaug; Oterhals, Åge; Ween, Ola; Halstensen, Alfred; Gudbrandsen, Oddrun Anita (Peer reviewed; Journal article, 2018-11-22)Hypertension is the leading risk factor for cardiovascular disease, and prevention of high blood pressure through diet and lifestyle should be a preferred approach. High intake of fish is associated with lower blood pressure, ... -
Comparison of pre-analytical conditions for quantification of serotonin in platelet-poor plasma
Volkmann, Hilde Løland Von; Brønstad, Ingeborg; Fiskerstrand, Torunn; Gudbrandsen, Oddrun Anita (Peer reviewed; Journal article, 2019)Background: Reported concentrations of serotonin in platelet-poor plasma (PPP) in healthy subjects vary widely due to different pre-analytical procedures. Aim: To examine how different pre-analytical conditions affect the ... -
Consumption of a light meal affects serum concentrations of one-carbon metabolites and B-vitamins. A clinical intervention study
Helland, Anita; Bratlie, Marianne; Hagen, Ingrid Valheim; Midttun, Øivind; Ulvik, Arve; Mellgren, Gunnar; Ueland, Per Magne; Gudbrandsen, Oddrun Anita (Journal article; Peer reviewed, 2022)The transfer of one-carbon units between molecules in metabolic pathways is essential for maintaining cellular homeostasis, but little is known about whether the circulating concentrations of metabolites involved in the ... -
Daily intake of protein from cod residual material lowers serum concentrations of nonesterified fatty acids in overweight healthy adults: A randomized double-blind pilot study
Vildmyren, Iselin Thowsen; Cao, Huy John Vu; Haug, Lina Bowitz; Valand, Ida Ulrikke; Eng, Øyvin Andre Solberg; Oterhals, Åge; Austgulen, Maren Hoff; Halstensen, Alfred; Mellgren, Gunnar; Gudbrandsen, Oddrun Anita (Peer reviewed; Journal article, 2018-06-05)Improved process technologies have allowed fishing vessels to utilize residuals from cod fillet production (head, backbone, skin, cuttings, and entrails) and convert this to high-quality protein powders for human consumption. ... -
A diet containing cod backbone proteins attenuated the development of mesangial sclerosis and tubular dysfunction in male obese BTBR ob/ob mice
O'Keeffe, Maria; Oterhals, Åge; Weishaupt, Hrafn; Leh, Sabine; Ulvik, Arve; Ueland, Per Magne; Halstensen, Alfred; Marti, Hans Peter; Gudbrandsen, Oddrun Anita (Journal article; Peer reviewed, 2023)Purpose The obese black and tan, brachyuric (BTBR) ob/ob mouse spontaneously develops features comparable to human diabetic nephropathy. The primary aim of the present study was to investigate if a diet containing fish ... -
Dietary fish intake increased the concentration of soluble ACE2 in rats: can fish consumption reduce the risk of COVID-19 infection through interception of SARS-CoV-2 by soluble ACE2?
O'Keeffe, Maria; Oterhals, Åge; Vikøren, Linn Anja Slåke; Drotningsvik, Aslaug; Mellgren, Gunnar; Halstensen, Alfred; Gudbrandsen, Oddrun Anita (Journal article; Peer reviewed, 2023)The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) enters the cells after binding to the membrane-bound receptor angiotensin-converting enzyme 2 (ACE2), but this may be prevented through interception by soluble ... -
Different Dietary Ratios of Camelina Oil to Sandeel Oil Influence the Capacity to Synthesise and Deposit EPA and DHA in Zucker Fa/Fa Rats
Østbye, Tone-Kari K; Gudbrandsen, Oddrun Anita; Drotningsvik, Aslaug; Ruyter, Bente Synnøve; Berge, Gerd Marit; Vogt, Kjell Gjermund; Nilsson, Astrid (Journal article; Peer reviewed, 2023-05-17)Plant-based food provides more ALA (α-linolenic acid) and less EPA (eicosapentaenoic acid) and DHA (docosahexanoic acid) than marine food. Earlier studies indicate that cetoleic acid (22:1n-11) stimulates the n-3 pathway ... -
Efect of high intake of cod or salmon on serum total neopterin concentration: a randomised clinical trial
Helland, Anita; Bratlie, Marianne; Hagen, Ingrid V.; Midttun, Øivind; Sveier, Harald; Mellgren, Gunnar; Ueland, Per Magne; Gudbrandsen, Oddrun Anita (Journal article; Peer reviewed, 2021)Purpose Primarily, to investigate the effect of high intake of cod (lean fish) or salmon (fatty fish) on serum concentration of total neopterin, a marker of cellular immune activation that is associated with cardiovascular ... -
Effect of cod residual protein supplementation on markers of glucose regulation in lean adults: A randomized double-blind study
Vildmyren, Iselin; Halstensen, Alfred; McCann, Adrian; Midttun, Øivind; Ueland, Per Magne; Oterhals, Åge; Gudbrandsen, Oddrun Anita (Journal article; Peer reviewed, 2020)Large quantities of protein-rich cod residuals, which are currently discarded, could be utilized for human consumption. Although fish fillet intake is related to beneficial health effects, little is known about the potential ... -
Effects of baked and raw salmon fillet on lipids and n-3 PUFAs in serum and tissues in Zucker fa/fa rats
Vikøren, Linn Anja Slåke; Drotningsvik, Aslaug; Bergseth, Marthe Tønder; Mjøs, Svein Are; Mola, Nazanin; Leh, Sabine Maria; Mellgren, Gunnar; Gudbrandsen, Oddrun Anita (Peer reviewed; Journal article, 2017)Knowledge of the health impact of consuming heat-treated versus raw fish fillet is limited. To investigate effects of baked or raw salmon fillet intake on lipids and n-3 PUFAs in serum and tissues, obese Zucker fa/fa rats ... -
Effects of diets containing fish oils or fish oil concentrates with high cetoleic acid content on the circulating cholesterol concentration in rodents. A systematic review and meta-analysis
Mjaatveit, Margrete; Oldernes, Helle; Gudbrandsen, Oddrun Anita (Journal article; Peer reviewed, 2023)Hypercholesterolaemia is a major risk factor for CVD. Fish intake is associated with lower risk of CVD, whereas supplementation with n-3 long-chain PUFA (LC-PUFA) has little effect on the cholesterol concentration. We ... -
Effects of duodenal switch alone or in combination with sleeve gastrectomy on body weight and lipid metabolism in rats
Gudbrandsen, Oddrun Anita; Kodama, Yosuke; Mjøs, Svein Are; Zhao, Chun-Mei; Johannesen, Helene; Brattbakk, Hans-Richard; Haugen, Christine; Kulseng, Bård Eirik; Mellgren, Gunnar; Chen, Duan (Peer reviewed; Journal article, 2014)Background: A combined procedure of sleeve gastrectomy and duodenal switch (SG+DS) has been applied to the treatment of super obesity. The aim of the present study was to test whether duodenal switch alone (DS) leads to ... -
Effects of high intake of cod or salmon on gut microbiota profile, faecal output and serum concentrations of lipids and bile acids in overweight adults: a randomised clinical trial
Bratlie, Marianne; Hagen, Ingrid Valheim; Helland, Anita; Erchinger, Friedemann Georg; Midttun, Øivind; Ueland, Per Magne; Rosenlund, Grethe; Sveier, Harald; Mellgren, Gunnar; Hausken, Trygve; Gudbrandsen, Oddrun Anita (Journal article; Peer reviewed, 2020-10-27)Purpose To explore whether high intake of cod or salmon would affect gut microbiota profile, faecal output and serum concentrations of lipids and bile acids. Methods Seventy-six adults with overweight/obesity with no ... -
Effects of intact and hydrolysed blue whiting proteins on blood pressure and markers of kidney function in obese Zucker fa/fa rats
Drotningsvik, Aslaug; Oterhals, Åge; Mjøs, Svein Are; Vikøren, Linn Anja Slåke; Flesland, Ola; Gudbrandsen, Oddrun Anita (Journal article; Peer reviewed, 2021)Purpose To investigate the effects of diets containing intact or hydrolysed proteins from blue whiting (Micromesistius poutassou) on the development of high blood pressure and markers of kidney function in obese Zucker ... -
Energy intake, nutritional status and weight reduction in patients one year after laparoscopic sleeve gastrectomy
Gjessing, Hanne Rosendahl; Nielsen, Hans Jørgen; Mellgren, Gunnar; Gudbrandsen, Oddrun Anita (Peer reviewed; Journal article, 2013-07-30)Background: Laparoscopic sleeve gastrectomy (LSG) is increasingly popular due to its efficiency in reducing excess weight, however little is known about the nutritional status in patients after surgery. Purpose: To investigate ... -
Five salmon dinners per week were not sufficient to prevent the reduction in serum vitamin D in autumn at 60° north latitude: A randomised trial
Bratlie, Marianne; Hagen, Ingrid Valheim; Helland, Anita; Midttun, Øivind; Ulvik, Arve; Rosenlund, Grethe; Sveier, Harald; Mellgren, Gunnar; Ueland, Per Magne; Gudbrandsen, Oddrun Anita (Journal article; Peer reviewed, 2020)Low serum concentrations of several vitamins have been linked to increased risk of diseases including insulin resistance and type 2 diabetes (T2D). Fish is a good source of several vitamins, and the prevalence of T2D is ...