Blar i Bergen Open Research Archive på forfatter "Gomes, Ana S."
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Anorectic role of high dietary leucine in farmed Atlantic salmon (Salmo salar L.): Effects on feed intake, growth, amino acid transporters and appetite-control neuropeptides
Lai, Floriana; Comesaña, Sara; Gomes, Ana S.; Flatejord, Daniel; Tolås, Ingvill; Espe, Marit; De Santis, Christian; Hartviksen, Mali B.; Verri, Tiziano; Soengas, Jose L.; Rønnestad, Ivar (Journal article; Peer reviewed, 2023)Leucine has been identified to modulate feed intake and energy homeostasis in fish as in other vertebrates. Under allostatic conditions, energy expenditure may change, and adjustments to the processes that govern the energy ... -
Brain Distribution of 10 cart Transcripts and Their Response to 4 Days of Fasting in Atlantic Salmon (Salmo salar L.)
Kalananthan, Tharmini; Gomes, Ana S.; Lai, Floriana; Tolås, Ingvill; Jordal, Ann-Elise O.; Norland, Sissel; Murashita, Koji; Rønnestad, Ivar (Journal article; Peer reviewed, 2021-10-25)Cocaine- and amphetamine-regulated transcript (CART) has been known to be involved in feeding and energy balance in mammals, acting as an anorexigenic neuropeptide in hypothalamus. In Atlantic salmon, little is known about ... -
Effects of short term fasting on mRNA expression of ghrelin and the peptide transporters PepT1 and 2 in Atlantic salmon (Salmo salar)
Del Vecchio, Gianmarco; Lai, Floriana; Gomes, Ana S.; Verri, Tiziano; Kalananthan, Tharmini; Barca, Amilcare; Handeland, Sigurd Olav; Rønnestad, Ivar (Journal article; Peer reviewed, 2021)Food intake is a vital process that supplies necessary energy and essential nutrients to the body. Information regarding luminal composition in the gastrointestinal tract (GIT) collected through mechanical and nutrient ... -
Functional characterization of Atlantic salmon (Salmo salar L.) PepT2 transporters
Vacca, Francesca; Gomes, Ana S.; Murashita, Koji; Cinquetti, Raffella; Roseti, Cristina; Barca, Amilcare; Rønnestad, Ivar; Verri, Tiziano; Bossi, Elena (Journal article; Peer reviewed, 2022)The high-affinity/low-capacity system Slc15a2 (PepT2) is responsible for the reuptake of di/tripeptides from the renal proximal tubule, but it also operates in many other tissues and organs. Information regarding PepT2 in ... -
Hypothalamic agrp and pomc mRNA Responses to Gastrointestinal Fullness and Fasting in Atlantic Salmon (Salmo salar, L.)
Kalananthan, Tharmini; Murashita, Koji; Rønnestad, Ivar; Ishigaki, Mitsumasa; Takahashi, Kota; Silva, Marta Sofia; Wakabayashi, Yuki; Lai, Floriana; Shimizu, Munetaka; Nilsen, Tom Ole; Martinez, Enrique Pino; Gomes, Ana S. (Journal article; Peer reviewed, 2020-02-11)The orexigenic agouti-related protein (AgRP) and the anorexigenic pro-opiomelanocortin (POMC) are crucial players in the control of feed intake in vertebrates, yet their role in teleosts has not been fully established. ... -
Identification and characterization of the Atlantic salmon peptide transporter 1a
Gomes, Ana S.; Vacca, Francesca; Cinquetti, Raffaella; Murashita, Koji; Barca, Amilcare; Bossi, Elena; Rønnestad, Ivar; Verri, Tiziano (Journal article; Peer reviewed, 2020)Peptide transporter 1 (PepT1) mediates the uptake of dietary di-/tripeptides in vertebrates. However, in teleost fish gut, more than one PepT1-type transporter might operate, because of teleost-specific whole gen(om)e ... -
Impact of long-term fasting on the stomach-hypothalamus appetite regulating genes in Atlantic salmon postsmolts
Kalananthan, Tharmini; Folkedal, Ole; Gomes, Ana S.; Lai, Floriana; Handeland, Sigurd Olav; Tolås, Ingvill; Gelebart, Virginie; Rønnestad, Ivar (Journal article; Peer reviewed, 2023)Atlantic salmon will experience periods of fasting during its lifecycle. In nature, prolonged fasting periods occur owing to seasonal fluctuations in available feeds, migration or in relation to reproduction. In a culture ... -
Leucine did not stimulate growth and accretion in either stressed or unstressed Atlantic salmon
Espe, Marit; Lai, Floriana; Gomes, Ana S.; De Santis, Christian; Hartviksen, Mali B.; Holen, Elisabeth; Rønnestad, Ivar (Journal article; Peer reviewed, 2021)The aim of the current trial was to test whether leucine affected growth and accretion including test any effects on leucine upon stress. Quadruplicate tanks each containing 50 Atlantic salmon (Salmo salar) (mean start ... -
Light conditions during Atlantic salmon embryogenesis affect key neuropeptides in the melanocortin system during transition from endogenous to exogenous feeding
Norland, Sissel; Gomes, Ana S.; Rønnestad, Ivar; Helvik, Jon Vidar; Eilertsen, Mariann (Journal article; Peer reviewed, 2023)During the first feeding period, fish will adapt to exogenous feeding as their endogenous source of nutrients is depleted. This requires the development of a functional physiological system to control active search for ... -
Mapping key neuropeptides involved in the melanocortin system in Atlantic salmon (Salmo salar) brain
Norland, Sissel; Eilertsen, Mariann; Rønnestad, Ivar; Helvik, Jon Vidar; Gomes, Ana S. (Journal article; Peer reviewed, 2023)The melanocortin system is a key regulator of appetite and food intake in vertebrates. This system includes the neuropeptides neuropeptide y (NPY), agouti-related peptide (AGRP), cocaine- and amphetamine-regulated transcript ... -
The Melanocortin System in Atlantic Salmon (Salmo salar L.) and Its Role in Appetite Control
Kalananthan, Tharmini; Lai, Floriana; Gomes, Ana S.; Murashita, Koji; Handeland, Sigurd O; Rønnestad, Ivar (Journal article; Peer reviewed, 2020-08-21)The melanocortin system is a key neuroendocrine network involved in the control of food intake and energy homeostasis in vertebrates. Within the hypothalamus, the system comprises two main distinct neuronal cell populations ... -
The peptide transporter 1a of the zebrafish Danio rerio, an emerging model in nutrigenomics and nutrition research: Molecular characterization, functional properties, and expression analysis
Vacca, Francesca; Barca, Amilcare; Gomes, Ana S.; Mazzei, Aurora; Piccinni, Barbara; Cinquetti, Raffaella; Del Vecchio, Gianmarco; Romano, Alessandro; Rønnestad, Ivar; Bossi, Elena; Verri, Tiziano (Peer reviewed; Journal article, 2019-12-19)Background: Peptide transporter 1 (PepT1, alias Slc15a1) mediates the uptake of dietary di/tripeptides in all vertebrates. However, in teleost fish, more than one PepT1-type transporter might function, due to specific whole ... -
Rearing conditions and automated feed distribution systems for zebrafish (Danio rerio)
del Veccio, Gianmarco; Mazzei, Aurora; Schiavone, Roberta; Gomes, Ana S.; Frangelli, Giovanni; Sala, Tomasso; Fantino, Stefania; Brocca, Marco G.A.; Barca, Amilcare; Rønnestad, Ivar; Verri, Tiziano (Journal article; Peer reviewed, 2022)Zebrafish (Danio rerio) is a well-established animal model, used in a number of research areas. In the last decade, it has also emerged as a tool to evaluate the effects of diets and dietary components and to test novel ... -
Regional Expression of npy mRNA Paralogs in the Brain of Atlantic Salmon (Salmo salar, L.) and Response to Fasting
Tolås, Ingvill; Kalananthan, Tharmini; Gomes, Ana S.; Lai, Floriana; Norland, Sissel; Murashita, Koji; Rønnestad, Ivar (Journal article; Peer reviewed, 2021-08-26)Neuropeptide Y (NPY) is known as a potent orexigenic signal in vertebrates, but its role in Atlantic salmon has not yet been fully established. In this study, we identified three npy paralogs, named npya1, npya2, and npyb, ... -
The stress response in Atlantic salmon (Salmo salar L.): identification and functional characterization of the corticotropin-releasing factor (crf) paralogs
Lai, Floriana; Royan, Muhammad Rahmad; Gomes, Ana S.; Espe, Marit; Aksnes, Anders; Norberg, Birgitta; Gelebart, Virginie; Rønnestad, Ivar (Journal article; Peer reviewed, 2021)Corticotropin-Releasing Factor (CRF) is one of the main mediators of the Hypothalamic-Pituitary–Interrenal (HPI) axis to stress response. In Atlantic salmon, a comparative understanding of the crf1 paralogs role in the ... -
The teleost fish PepT1-type peptide transporters and their relationships with neutral and charged substrates
Vacca, Francesca; Gomes, Ana S.; De Gennaro, Marco; Rønnestad, Ivar; Bossi, Elena; Verri, Tiziano (Journal article; Peer reviewed, 2023)In teleosts, two PepT1-type (Slc15a1) transporters, i.e., PepT1a and PepT1b, are expressed at the intestinal level. They translocate charged di/tripeptides with different efficiency, which depends on the position of the ...