Blar i Bergen Open Research Archive på forfatter "Krantz, Ian D."
-
A cohesin-independent role for NIPBL at promoters provides insights in CdLS
Zuin, Jessica; Franke, Vedran; van Ijcken, Wilfred F.J.; van der Sloot, Antoine A.J.; Krantz, Ian D.; van der Reijden, Michael I.J.A.; Nakato, Ryuichiro; Lenhard, Boris; Wendt, Kerstin S. (Peer reviewed; Journal article, 2014-02-13)The cohesin complex is crucial for chromosome segregation during mitosis and has recently also been implicated in transcriptional regulation and chromatin architecture. The NIPBL protein is required for the loading of ... -
Neuronal genes deregulated in Cornelia de Lange Syndrome respond to removal and re-expression of cohesin
Weiss, Felix D.; Calderon, Lesly; Wang, Yi-Fang; Georgieva, Radina; Guo, Ya; Cvetesic, Nevena; Kaur, Maninder; Dharmalingam, Gopuraja; Krantz, Ian D.; Lenhard, Boris; Fisher, Amanda G.; Merkenschlager, Matthias (Journal article; Peer reviewed, 2021)Cornelia de Lange Syndrome (CdLS) is a human developmental disorder caused by mutations that compromise the function of cohesin, a major regulator of 3D genome organization. Cognitive impairment is a universal and as yet ...