• An idiosyncratic zonated stroma encapsulates desmoplastic liver metastases and originates from injured liver 

      Fernández Moro, Carlos; Geyer, Natalie; Harrizi, Sara; Hamidi, Yousra; Söderqvist, Sara; Kuznyecov, Danyil; Tidholm Qvist, Evelina; Salmonson Schaad, Media; Hermann, Laura; Lindberg, Amanda; Heuchel, Rainer L.; Martín-Bernabé, Alfonso; Dhanjal, Soniya; Navis, Anna C.; Villard, Christina; del Valle, Andrea C.; Bozóky, Lorand; Sparrelid, Ernesto; Dirix, Luc; Strell, Carina; Östman, Arne; Schmierer, Bernhard; Vermeulen, Peter B.; Engstrand, Jennie; Bozóky, Béla; Gerling, Marco (Journal article; Peer reviewed, 2023)
      A perimetastatic capsule is a strong positive prognostic factor in liver metastases, but its origin remains unclear. Here, we systematically quantify the capsule’s extent and cellular composition in 263 patients with ...
    • Spatial immunophenotyping of the tumour microenvironment in non–small cell lung cancer 

      Backman, Max; Strell, Carina; Lindberg, Amanda; Mattsson, Johanna S.M.; Elfving, Hedvig; Brunnström, Hans; O'Reilly, Aine; Bosic, Martina; Gulyas, Miklos; Isaksson, Johan; Botling, Johan; Kärre, Klas; Jirström, Karin; Lamberg, Kristina; Pontén, Fredrik; Leandersson, Karin; Mezheyeuski, Artur; Micke, Patrick (Journal article; Peer reviewed, 2023)
      Introduction: Immune cells in the tumour microenvironment are associated with prognosis and response to therapy. We aimed to comprehensively characterise the spatial immune phenotypes in the mutational and clinicopathological ...