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    • Functional and Binding H1N1pdm09-Specific Antibody Responses in Occasionally and Repeatedly Vaccinated Healthcare Workers: A Five-Year Study (2009-2014) 

      Amdam, Håkon; Madsen, Anders; Zhou, Fan; Bansal, Amit; Trieu, Mai Chi; Cox, Rebecca Jane (Journal article; Peer reviewed, 2021)
      Background: In 2009, a novel influenza A/H1N1pdm09 emerged and caused a pandemic. This strain continued to circulate and was therefore included in the seasonal vaccines up to the 2016/2017-season. This provided a unique ...

    • Functional annotation of human long noncoding RNAs via molecular phenotyping 

      Ramilowski, Jordan; Yip, Chiu Wai Mickey; Agrawal, Saumya; Chang, Jen-Chien; Ciani, Yari; Kulakovskiy, Ivan; Mendez, Mickaël; Ching Ooi, Jasmine Li; Ouyang, John F; Parkinson, Nick; Kasukawa, Takeya; Kauppinen, Sakari; Kere, Juha; Lenhard, Boris; Schneider, Claudio; Suzuki, Harukazu; Yagi, Ken; De Hoon, Michiel J L; Shin, Jay W; Piero, Carninci (Journal article; Peer reviewed, 2020)
      Long noncoding RNAs (lncRNAs) constitute the majority of transcripts in the mammalian genomes, and yet, their functions remain largely unknown. As part of the FANTOM6 project, we systematically knocked down the expression ...

    • Functional brain networks in the schizophrenia spectrum and bipolar disorder with psychosis 

      van Dellen, Edwin; Börner, Corinna; Schutte, Maya; van Montfort, Simone; Abramovic, Lucija; Boks, Marco P.; Cahn, Wiepke; van Haren, Neeltje E.M.; Mandl, René; Stam, Cornelis J.; Sommer, Iris Else Clara (Journal article; Peer reviewed, 2020)
      Psychotic experiences have been proposed to lie on a spectrum, ranging from subclinical experiences to treatment-resistant schizophrenia. We aimed to characterize functional connectivity and brain network characteristics ...

    • Functional changes in GABA and glutamate during motor learning 

      Bell, Tiffany K; Craven, Alexander R.; Hugdahl, Kenneth Jan; Noeske, Ralph; Harris, Ashley D (Journal article; Peer reviewed, 2023)
      Functional magnetic resonance spectroscopy (fMRS) of GABA at 3 T poses additional challenges compared with fMRS of other metabolites because of the difficulties of measuring GABA levels; GABA is present in the brain at ...

    • Functional characterization of all-trans retinoic acid-induced differentiation factor (ATRAID) 

      Mehrasa, Roya; Cristea, Ileana; Bredrup, Cecilie; Rødahl, Eyvind; Bruland, Ove (Journal article; Peer reviewed, 2023)
      All-trans retinoic acid-induced differentiation (ATRAID) factor was first identified in HL60 cells. Several mRNA isoforms exist, but the respective proteins have not been fully characterized. In transfected cells expressing ...

    • Functional characterization of Atlantic salmon (Salmo salar L.) PepT2 transporters 

      Vacca, Francesca; Gomes, Ana S.; Murashita, Koji; Cinquetti, Raffella; Roseti, Cristina; Barca, Amilcare; Rønnestad, Ivar; Verri, Tiziano; Bossi, Elena (Journal article; Peer reviewed, 2022)
      The high-affinity/low-capacity system Slc15a2 (PepT2) is responsible for the reuptake of di/tripeptides from the renal proximal tubule, but it also operates in many other tissues and organs. Information regarding PepT2 in ...

    • Functional connectome differences in individuals with hallucinations across the psychosis continuum 

      Schutte, Maya J. L.; Bohlken, Marc M.; Collin, Guusje; Abramovic, Lucija; Boks, Marco P. M.; Cahn, Wiepke; Dauwan, Meenakshi; van Dellen, Edwin; van Haren, Neeltje E. M.; Hugdahl, Kenneth; Koops, Sanne; Mandl, René C. W.; Sommer, Iris E. C. (Journal article; Peer reviewed, 2021)
      Hallucinations may arise from an imbalance between sensory and higher cognitive brain regions, reflected by alterations in functional connectivity. It is unknown whether hallucinations across the psychosis continuum exhibit ...

    • Functional Data Analysis of Non-manual Marking of Questions in Kazakh-Russian Sign Language 

      Kuznetsova, Anna; Imashev, Alfarabi; Mukushev, Medet; Sandygulova, Anara; Kimmelman, Vadim (Chapter, 2022)
      This paper is a continuation of Kuznetsova et al. (2021), which described non-manual markers of polar and wh-questions in comparison with statements in an NLP dataset of Kazakh-Russian Sign Language (KRSL) using Computer ...

    • Functional evaluation of 16 SCHAD missense variants: Only amino acid substitutions causing congenital hyperinsulinism of infancy lead to loss-of-function phenotypes in vitro 

      Velasco Pinto, Kelly; St-Louis, Johanna; Hovland, Henrikke N.; Thompson, Nels; Ottesen, Åsta; Choi, Man Hung; Pedersen, Line; Njølstad, Pål Rasmus; Arnesen, Thomas; Fjeld, Karianne; Aukrust, Ingvild; Myklebust, Line Merethe; Molven, Anders (Journal article; Peer reviewed, 2021)
      Short‐chain 3‐hydroxyacyl‐CoA dehydrogenase (SCHAD), encoded by the HADH gene, is a ubiquitously expressed mitochondrial enzyme involved in fatty acid oxidation. This protein also plays a role in insulin secretion as ...

    • Functional Evolution of Clustered Aquaporin Genes Reveals Insights into the Oceanic Success of Teleost Eggs 

      Ferré, Alba; Chauvigné, Francois; Vlasova, Anna; Norberg, Birgitta; Bargelloni, Luca; Guigó, Roderic; Finn, Roderick Nigel; Cerdà, Joan (Journal article; Peer reviewed, 2023)
      Aquaporin-mediated oocyte hydration is considered important for the evolution of pelagic eggs and the radiative success of marine teleosts. However, the molecular regulatory mechanisms controlling this vital process are ...

    • Functional inequalities on path space of sub-Riemannian manifolds and applications 

      Cheng, Li-Juan; Grong, Erlend; Thalmaier, Anton (Journal article; Peer reviewed, 2021)
      We consider the path space of a manifold with a measure induced by a stochastic flow with an infinitesimal generator that is hypoelliptic, but not elliptic. These generators can be seen as sub-Laplacians of a sub-Riemannian ...

    • Functional properties of GABAA receptors of AII amacrine cells of the rat retina 

      Beltran Matas, Pablo; Hartveit, Espen; Veruki, Margaret Lin (Journal article, 2023-04-05)
      Amacrine cells are a highly diverse group of inhibitory retinal interneurons that sculpt the responses of bipolar cells, ganglion cells, and other amacrine cells. They integrate excitatory inputs from bipolar cells and ...

    • Functional specialization of Aurora kinase homologs during oogenic meiosis in the tunicate Oikopleura dioica 

      Feng, Haiyang; Thompson, Eric Malcolm (Journal article; Peer reviewed, 2023)
      A single Aurora kinase found in non-vertebrate deuterostomes is assumed to represent the ancestor of vertebrate Auroras A/B/C. However, the tunicate Oikopleura dioica, a member of the sister group to vertebrates, possesses ...

    • Functional traits of alpine plant communities show long-term resistance to changing herbivore densities 

      Vuorinen, Katariina Elsa Maria; Austrheim, Gunnar; Mysterud, Atle; Gya, Ragnhild; Vandvik, Vigdis; Grytnes, John Arvid; Speed, James David Mervyn (Journal article; Peer reviewed, 2021)
      Herbivores shape vegetation by suppressing certain plant species while benefitting others. By thus modifying plant species functional composition, herbivores affect carbon cycling, albedo, vegetation structure and species' ...

    • Functionalism and Personal Identity – The Case of Mr. Jones 

      Karlsen, Gunnar; Granberg, Anne (Journal article; Peer reviewed, 2021)
      Stanisław Lem’s short story Are you there Mr. Jones?, first published in 1955, is set in a courtroom. The plaintiff is Cybernetics Company – a provider of prosthetics – and the defendant is Harry Jones, a race-car driver. ...

    • Functionality of the Crosswise Model for Assessing Sensitive or Transgressive Behavior: A Systematic Review and Meta-Analysis 

      Sagoe, Dominic; Cruyff, Maarten; Spendiff, Owen; Chegeni, Razieh; de Hon, Olivier; Saugy, Martial; van der Heijden, Peter G. M.; Petróczi, Andrea (Journal article; Peer reviewed, 2021)
      Tools for reliable assessment of socially sensitive or transgressive behavior warrant constant development. Among them, the Crosswise Model (CM) has gained considerable attention. We systematically reviewed and meta-analyzed ...

    • Functionalization of the Imidazole Backbone by Means of a Tailored and Optimized Oxidative Heck Cross-Coupling 

      Cirillo, Davide; Angelucci, Francesco; Bjørsvik, Hans-René (Journal article; Peer reviewed, 2020)
      A general and selective Pd-catalyzed cross-coupling of aromatic boronic acids with vinyl-imidazoles is disclosed. Unlike most cross-coupling reactions, this method operates well in absence of bases avoiding the formation ...

    • Functionalizing Collagen Membranes with MSC-Conditioned Media Promotes Guided Bone Regeneration in Rat Calvarial Defects 

      Shanbhag, Siddharth; Kampleitner, Carina; Al-Sharabi, Niyaz Abdulbaqi Abdulmajid; Mohamed-Ahmed, Samih Salah Eldin Mahgoub; Apaza Alccayhuaman, Karol Ali; Heimel, Patrick; Tangl, Stefan; Beinlich, Andreas Michael; Rana, Neha; Sanz, Mariano; Kristoffersen, Einar Klæboe; Mustafa, Kamal Babikeir Elnour; Gruber, Reinhard (Journal article; Peer reviewed, 2023-02-28)
      Functionalizing biomaterials with conditioned media (CM) from mesenchymal stromal cells (MSC) is a promising strategy for enhancing the outcomes of guided bone regeneration (GBR). This study aimed to evaluate the bone ...

    • Fur glowing under ultraviolet: in situ analysis of porphyrin accumulation in the skin appendages of mammals 

      Toussaint, Séverine L. D.; Ponstein, Jasper; Thoury, Mathieu; Métivier, Rémi; Kalthoff, Daniela C.; Habermeyer, Benoît; Guilard, Roger; Bock, Steffen; Mortensen, Peter; Sandberg, Sverre; Gueriau, Pierre; Amson, Eli (Journal article; Peer reviewed, 2023)
      Examples of photoluminescence (PL) are being reported with increasing frequency in a wide range of organisms from diverse ecosystems. However, the chemical basis of this PL remains poorly defined, and our understanding of ...

    • Further investigations on permutation based constructions of bent functions 

      Li, Kangquan; Li, Chunlei; Helleseth, Tor; Qu, Longjiang (Journal article; Peer reviewed, 2023)
      Constructing bent functions by composing a Boolean function with a permutation was introduced by Hou and Langevin in 1997. The approach appears simple but heavily depends on the construction of desirable permutations. In ...