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dc.contributor.authorMikkelsen, Rasmus Tyrsted
dc.contributor.authorOvergaard, Søren
dc.contributor.authorPedersen, Alma B.
dc.contributor.authorKärrholm, Johan
dc.contributor.authorRolfson, Ola
dc.contributor.authorFenstad, Anne Marie
dc.contributor.authorFurnes, Ove Nord
dc.contributor.authorHallan, Geir
dc.contributor.authorMäkelä, Keijo
dc.contributor.authorEskelinen, Antti
dc.contributor.authorVarnum, Claus
dc.date.accessioned2024-03-12T14:26:15Z
dc.date.available2024-03-12T14:26:15Z
dc.date.created2023-07-17T12:26:54Z
dc.date.issued2023
dc.identifier.issn1745-3674
dc.identifier.urihttps://hdl.handle.net/11250/3122007
dc.description.abstractBackground and purpose: The bearings with the best survivorship for young patients with total hip arthroplasty (THA) should be identified. We compared hazard ratios (HR) of revision of primary stemmed cementless THAs with metal-on-metal (MoM), ceramic-on-ceramic (CoC), and ceramic-on-highly-crosslinked-polyethylene (CoXLP) with that of metal-on-highly-crosslinked-polyethylene (MoXLP) bearings in patients aged 20–55 years with primary osteoarthritis or childhood hip disorders. Patients and methods: From the Nordic Arthroplasty Register Association dataset we included 1,813 MoM, 3,615 CoC, 5,947 CoXLP, and 10,219 MoXLP THA in patients operated on between 2005 and 2017 in a prospective cohort study. We used the Kaplan–Meier estimator for THA survivorship and Cox regression to estimate HR of revision adjusted for confounders (including 95% confidence intervals [CI]). MoXLP was used as reference. HRs were calculated during 3 intervals (0–2, 2–7, and 7–13 years) to meet the assumption of proportional hazards. Results: Median follow-up was 5 years for MoXLP, 10 years for MoM, 6 years for CoC, and 4 years for CoXLP. 13-year Kaplan–Meier survival estimates were 95% (CI 94–95) for MoXLP, 82% (CI 80–84) for MoM, 93% (CI 92–95) for CoC, and 93% (CI 92–94) for CoXLP bearings. MoM had higher 2–7 and 7–13 years’ adjusted HRs of revision (3.6, CI 2.3–5.7 and 4.1, CI 1.7–10). MoXLP, CoC, and CoXLP had similar HRs in all 3 periods. The 7–13-year adjusted HRs of revision of CoC and CoXLP were statistically non-significantly higher. Conclusion: In young patients, MoXLP for primary cementless THA had higher revision-free survival and lower HR for revision than MoM bearings. Longer follow-up is needed to compare MoXLP, CoC, and CoXLP.en_US
dc.language.isoengen_US
dc.publisherMedical Journals Swedenen_US
dc.rightsNavngivelse-Ikkekommersiell 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/deed.no*
dc.titleDoes choice of bearings influence the survival of cement-less total hip arthroplasty in patients aged 20–55 years? Comparison of 21,594 patients reported to the Nordic Arthroplasty Register Association dataset 2005–2017en_US
dc.typeJournal articleen_US
dc.typePeer revieweden_US
dc.description.versionpublishedVersionen_US
dc.rights.holderCopyright 2023 the authorsen_US
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1
dc.identifier.doi10.2340/17453674.2023.13384
dc.identifier.cristin2162500
dc.source.journalActa Orthopaedicaen_US
dc.source.pagenumber266-273en_US
dc.identifier.citationActa Orthopaedica. 2023, 94, 266-273.en_US
dc.source.volume94en_US


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Navngivelse-Ikkekommersiell 4.0 Internasjonal
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