Browsing Master theses by Author "Lundberg, Bjørn Christian"
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Using iPSC-derived cortical organoids to study disease mechanisms of POLG-disease and explore new therapeutic strategies
Lundberg, Bjørn Christian (Master thesis, 2023-07-03)POLG-related diseases are a set of severe mitochondrial myopathies caused by a mutation in the POLG gene. The POLG gene encodes for the catalytic subunit of the mitochondrial DNA (mtDNA) polymerase gamma (Pol-γ). Pol-γ is ...