Department of Clinical Science: Nye registreringer
Viser treff 41-60 av 2309
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Clinical features and risk factors for death in acute undifferentiated fever: A prospective observational study in rural community hospitals in six states of India
(Journal article; Peer reviewed, 2023)Background Acute undifferentiated fever (AUF) ranges from self-limiting illness to life-threatening infections, such as sepsis, malaria, dengue, leptospirosis and rickettsioses. Similar clinical presentation challenges ... -
Cross-trait genome-wide association analysis of C-reactive protein level and psychiatric disorders
(Journal article; Peer reviewed, 2023)C-reactive protein (CRP) tends to be elevated in individuals with psychiatric disorders. Recent findings have suggested a protective effect of the genetic liability to elevated CRP on schizophrenia risk and a causative ... -
Reduced Plasma Guanylin Levels Following Enterotoxigenic Escherichia coli-Induced Diarrhea
(Journal article; Peer reviewed, 2023)The intestinal peptide hormones guanylin (GN) and uroguanylin (UGN) interact with the epithelial cell receptor guanylate cyclase C to regulate fluid homeostasis. Some enterotoxigenic Escherichia coli (ETEC) produce heat-stable ... -
Vitamin B12 Deficiency (Un-)Detected Using Newborn Screening in Norway
(Journal article; Peer reviewed, 2023)Untreated vitamin B12 (B12) deficiency may cause delayed development in infants. Several newborn screening (NBS) programs have reported an increased detection rate of B12 deficiency when second-tier dried blood spot (DBS) ... -
Pleural Empyema Caused by Streptococcus intermedius and Fusobacterium nucleatum: A Distinct Entity of Pleural Infections
(Journal article; Peer reviewed, 2023)Background Many community-acquired pleural infections are caused by facultative and anaerobic bacteria from the human oral microbiota. The epidemiology, clinical characteristics, pathogenesis, and etiology of such ... -
Safety of hypoxic red blood cell administration in patients with transfusion-dependent hematological malignancies: An interim analysis
(Journal article; Peer reviewed, 2023)Anemia is a common symptom of hematological malignancies and red blood cell (RBC) transfusion is the primary supportive treatment, with many patients becoming transfusion dependent. Hemanext Inc. (Lexington, MA, United ... -
Operator radiation exposure in cardiac catheterization
(Doctoral thesis, 2024-03-22)Introduksjon Røntgenveiledete hjerteprosedyrer utsetter både pasient og operatør for ioniserende stråling. Selv om operatørdosen er en brøkdel av pasientdosen, kan en operatør utføre tusenvis av prosedyrer i løpet av en ... -
What determines who gets cardiac resynchronization therapy in Europe? A comparison between ESC-HF-LT registry, SwedeHF registry, and ESC-CRT Survey II
(Journal article; Peer reviewed, 2023)Aims Cardiac resynchronization therapy (CRT) is effective in heart failure with reduced ejection fraction (HFrEF) and dyssynchrony but is underutilized. In a cohort study, we identified clinical, organizational, and ... -
Expression of ANK3 moderates the association between childhood trauma and affective traits in severe mental disorders
(Journal article; Peer reviewed, 2023)Exposure to early life trauma increases the risk of psychopathology later in life. Here we investigated if ANK3 mRNA levels influence the relationship between childhood trauma experiences and clinical characteristics in ... -
Safety and efficacy of pegunigalsidase alfa in patients with Fabry disease who were previously treated with agalsidase alfa: results from BRIDGE, a phase 3 open-label study
(Journal article; Peer reviewed, 2023)Background Pegunigalsidase alfa is a novel, PEGylated α-galactosidase-A enzyme-replacement therapy approved in the EU and US to treat patients with Fabry disease (FD). Objective/methods BRIDGE is a phase 3 open-label, ... -
Long-term impact of gastropexy on use of acid-reducing medication, second operations for gastroesophageal reflux and subjective reflux symptoms after sleeve gastrectomy
(Journal article; Peer reviewed, 2023)We investigated whether adding gastropexy to sleeve gastrectomy (SG) reduced gastroesophageal reflux disease (GERD) in patients operated for severe obesity, assessed mainly by use of anti-reflux medication (ARM) and second ... -
Multimodality imaging in the immediate and long-term evaluation of bioresorbable vascular scaffolds : In patients with ST-elevation myocardial infarction
(Doctoral thesis, 2024-03-15)Introduksjon Akutt revaskularisering med primær perkutan koronar revaskularisering (PCI) er foretrukne strategi for pasienter med ST-elevasjons myokardielt infarkt (STEMI). Nåværende teknikk er å implantere stenter laget ... -
Cardiac troponin measurement at the point of care: educational recommendations on analytical and clinical aspects by the IFCC Committee on Clinical Applications of Cardiac Bio-Markers (IFCC C-CB)
(Journal article; Peer reviewed, 2023)The International Federation of Clinical Chemistry and Laboarator Medicine (IFCC) Committee on Clinical Applications of Cardiac Bio-Markers (C-CB) has provided evidence-based educational resources to aid and improve the ... -
Long-Term Outcomes of Invasive vs Conservative Strategies for Older Patients With Non–ST-Segment Elevation Acute Coronary Syndromes
(Journal article; Peer reviewed, 2023)Background Non–ST-segment elevation acute coronary syndrome (NSTE-ACS) is a frequent cause of hospital admission in older people, but clinical trials targeting this population are scarce. Objectives The After Eighty ... -
High number of hypoglycaemic episodes identified by CGM among home-dwelling older people with diabetes: an observational study in Norway
(Journal article; Peer reviewed, 2023)Background A scoping review from 2021 identified a lack of studies on the incidence, prevention and management of hypoglycaemia in home-dwelling older people with diabetes. The aim of this study was to investigate the ... -
Cardiac organ damage in systemic hypertension: Impact of gender, etiology, and comorbidities
(Doctoral thesis, 2024-03-15)Bakgrunn: Ukontrollert systemisk hypertensjon fører til økt risiko for kardiovaskulær sykdom og død både ved essensiell og sekundær hypertensjon. Den økte risikoen skyldes i stor grad utvikling av strukturelle og funksjonelle ... -
Randomized controlled trials and alternative study designs in surgical oncology
(Journal article; Peer reviewed, 2023)Surgery is central to the cure of most solid cancers and an integral part of modern multimodal cancer management for early and advanced stage cancers. Decisions made by surgeons and multidisciplinary team members are based ... -
Prenatal BRCA1 epimutations contribute significantly to triple-negative breast cancer development
(Journal article; Peer reviewed, 2023)Background Normal cell BRCA1 epimutations have been associated with increased risk of triple-negative breast cancer (TNBC). However, the fraction of TNBCs that may have BRCA1 epimutations as their underlying cause is ... -
The liver-heart axis in patients with severe obesity: the association between liver fibrosis and chronic myocardial injury may be explained by shared risk factors of cardiovascular disease
(Journal article; Peer reviewed, 2024)Background: Severe obesity is associated with increased risk of non-alcoholic fatty liver disease and cardiovascular disease. We hypothesized that liver fibrosis as quantified by the Enhanced Liver Fibrosis (ELF) test would ...