Browsing Department of Biomedicine by Document Types "Master thesis"
Now showing items 21-40 of 85
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Design of tumour-specific immunotherapies using dendritic cells – analyses of IL15-DC
(Master thesis, 2009-05-31)Immunotherapy of malignancies aims at activating the patient’s own immune system to fight the tumour affecting the patient. Even though the use of dendritic cells (DC) has shown promising results, the DC vaccination strategy ... -
Development and Characterization of an ex vivo Organotypic Non-Small Cell Lung Cancer Model to Study the Effect of Elevated Oxygen Treatment
(Master thesis, 2021-06-01)Lung cancer is a leading cause of cancer-related morbidity and mortality worldwide, and also the cancer-form responsible for most cancer related deaths in Norway. Non-small cell lung cancer (NSCLC) accounts for approximately ... -
Development of 3D in vitro Interaction Models for the Evaluation and Treatment of Brain Metastases
(Master thesis, 2021-06-01) -
EEG Analysis in Adults with Attention-Deficit-Hyperactivity-Disorder. Resting state and behavioural data analysis
(Master thesis, 2015-05-31)Introduction: Adults with attention-deficit/hyperactivity disorder (ADHD) are examined by electroencephalography (EEG). EEG is a non-invasive method to measure brain activity indirectly, by measuring voltage changes on the ... -
The effect of hyperbaric oxygen treatment on malignant progression in different breast cancer models in vivo
(Master thesis, 2016-07-01)Background: Hypoxia is an important feature of most solid tumors and has shown to serve as a mediator for aggressive tumor growth and malignant progression of cancer. A correlation between low oxygen tension in tumors and ... -
The effect of hyperbaric oxygen treatment, alone or in combination with 5-FU, on a MDA-MB-231 human mammary tumor model
(Master thesis, 2012-06-20)Background: Previous studies of hyperbaric oxygen (HBO) treatment on chemically induced and murine breast cancer models have shown promising results. This study was performed to elucidate the effects of HBO on a human ... -
Effect of miR-582-5p modulated cancer-associated fibroblasts on vulvar cancer cells
(Master thesis, 2022-06-01) -
An eGFP expressing immunodeficent mouse model with dsRED transfected mammary tumours, and the effect of hyperbaric oxygen treatment
(Master thesis, 2009-11-20)Previous studies have shown significant anti-tumour effects of hyperbaric oxygen (HBO) treatment on chemically induced mammary tumours. Thus, to answer whether HBO has a general anti-tumour effect on mammary tumours, the ... -
An electrophysiological study in freely exploring rats - Place cell properties and place field stability in the absence or presence of reward as a motivational factor.
(Master thesis, 2009-06-02)The activity of pyramidal cells in the hippocampus can be spatially modulated. Numerous studies have been performed examining their properties, like what influences the position of their firing fields or what effect changes ... -
Exploring the anti-leukemic effect of the combination treatment with Valproic acid, Lonidamine and Mycophenolate mofetil in acute myeloid leukemia
(Master thesis, 2015-06-01)An accumulation of immature myeloid progenitor cells at the expense of normal hematopoietic precursors characterizes the aggressive heterogeneous cancer acute myeloid leukemia (AML). It affects the bone marrow and peripheral ... -
Exploring the IBS Brain: Resting State Functional Connectivity and Machine Learning
(Master thesis, 2019-06-28) -
Expression, Purification, and Small Molecule Binding to Cysteine Sulfinic Acid Decarboxylase
(Master thesis, 2023-06-01)Cysteine Sulfinic acid decarboxylase (CSAD) is a PLP-dependent enzyme involved in the biosynthesis of taurine. It converts cysteine sulfinic acid (CSA) into hypotaurine. Hypotaurine is later oxidized into taurine, one of ... -
The Heart and a Fibrotic Interstitium
(Master thesis, 2009-05-29)Several acute and chronic diseases disposes for myocardial oedema and fibrosis, leading to impaired cardiac function, presumably as a result of an increased chamber stiffness. Mechanisms and adverse effects of both oedema ... -
High-dimensional Characterisation of rare cerebrospinal fluid cells in relapsing remitting multiple sclerosis patients
(Master thesis, 2023-06-01)Multiple Sclerosis (MS) is a chronic inflammatory and neurodegenerative disease of the central nervous system (CNS) and is the leading cause of neurological disability in young adults in North America and Europe, affecting ... -
The impact of different dietary sources of marine polyunsaturated fatty acids on the fatty acid composition of rat brain, liver and red blood cells.
(Master thesis, 2005-06)There is a general consensus that the physiological activity of fish oil can be ascribable to eicosapentaenoic acid (EPA, 20:5n-3) and docosahexaenoic acid (DHA, 22:6n-3). However, the form in which they are introduced in ... -
Impact of hypoxia on the expression of cell line markers and behavior of cultured glioma cell lines
(Master thesis, 2011-06-01)Glioblastoma multiforme (GBM) constitute over 50 % of primary brain tumors in adults. The tumor is heterogeneous and highly infiltrative. Its nature makes it extremely aggressive and incurable. Thus, today's treatment ... -
Improvement of a 3D model system for the evaluation and treatment of pancreatic ductal adenocarcinoma
(Master thesis, 2021-06-01) -
In vitro and in vivo studies of a novel blood brain barrier permeabilizing peptide K16ApoE
(Master thesis, 2016-05-30)Brain metastasis is a common and severe complication arising in up to 40 % of cancer patients. The prognoses for patients with brain metastases are dismal, with a median treated survival of around 10 months. Treatment of ... -
The in vitro effect of cytokine autoantibodies on Th17-differentiation and function
(Master thesis, 2023-06-01) -
In vitro study of a selective PI3K inhibitor on brain metastases
(Master thesis, 2020-06-17)