Browsing Department of Global Public Health and Primary Care by Journals "Scientific Reports"
Now showing items 1-16 of 16
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EWAS of post-COVID-19 patients shows methylation differences in the immune-response associated gene, IFI44L, three months after COVID-19 infection
(Journal article; Peer reviewed, 2022)Although substantial progress has been made in managing COVID-19, it is still difficult to predict a patient’s prognosis. We explored the epigenetic signatures of COVID-19 in peripheral blood using data from an ongoing ... -
Growth, clinical and neurodevelopmental outcomes at school age are similar for children who received 1‑year lamivudine or lopinavir/ritonavir HIV prophylaxis in early life
(Journal article; Peer reviewed, 2021)In the ANRS 12174 trial, HIV-exposed uninfected African neonates who received lopinavir-ritonavir (LPV/r) prophylaxis for 1 year exhibited slower growth from birth to week 50 compared with those receiving lamivudine (3TC). ... -
Heavy metals in children's blood from the rural region of Popokabaka, Democratic Republic of Congo: a cross-sectional study and spatial analysis
(Journal article; Peer reviewed, 2022)Exposure to heavy metals can affect cell differentiation, neurocognitive development, and growth during early life, even in low doses. Little is known about heavy metal exposure and its relationship with nutrition outcomes ... -
Identification of host biomarkers from dried blood spots for monitoring treatment response in extrapulmonary tuberculosis
(Journal article; Peer reviewed, 2023)There is a lack of objective tools for monitoring treatment response in extrapulmonary tuberculosis (EPTB). This study aimed to explore the utility of inflammatory biomarkers from the dry blood spots (DBS) as a tool for ... -
Incidence trends of airflow obstruction among European adults without asthma: a 20-year cohort study
(Journal article; Peer reviewed, 2020)Investigating COPD trends may help healthcare providers to forecast future disease burden. We estimated sex- and smoking-specific incidence trends of pre-bronchodilator airflow obstruction (AO) among adults without asthma ... -
IP-10 dried blood spots assay monitoring treatment efficacy in extrapulmonary tuberculosis in a low-resource setting
(Peer reviewed; Journal article, 2019-03-07)Treatment efficacy is difficult to evaluate in extrapulmonary tuberculosis (EPTB) patients. Interferon-γ inducible protein (IP-)10 has been suggested as a biomarker for response to treatment. We have investigated if IP-10 ... -
Lower risk of smoking-related cancer in individuals with familial hypercholesterolemia compared with controls: a prospective matched cohort study
(Peer reviewed; Journal article, 2019-12-17)According to guidelines, individuals with familial hypercholesterolemia (FH) shall receive lifestyle intervention and intensive lipid-lowering treatment from early in life to reduce the risk of coronary heart disease. Our ... -
Maize pollen diet enhances malaria mosquito longevity and infectivity to Plasmodium parasites in Ethiopia
(Journal article; Peer reviewed, 2023)Although larval diet quality may affect adult mosquito fitness, its impact on parasite development is scarce. Plant pollen from Zea mays, Typha latifolia, and Prosopis juliflora was ultraviolet-sterilized and examined for ... -
Maternal fever during pregnancy and offspring attention deficit hyperactivity disorder
(Peer reviewed; Journal article, 2019-07-02)Maternal fever during pregnancy is associated with several adverse child outcomes. We investigated associations between maternal fever and ADHD among offspring, as well as the sub-dimensions of ADHD - inattention and ... -
Mobility restrictions were associated with reductions in COVID-19 incidence early in the pandemic: evidence from a real-time evaluation in 34 countries
(Journal article; Peer reviewed, 2021)Most countries have implemented restrictions on mobility to prevent the spread of Coronavirus disease-19 (COVID-19), entailing considerable societal costs but, at least initially, based on limited evidence of effectiveness. ... -
MPT64 antigen detection test improves diagnosis of pediatric extrapulmonary tuberculosis in Mbeya, Tanzania
(Journal article; Peer reviewed, 2021)Pediatric extrapulmonary tuberculosis (EPTB) is a diagnostic challenge. A new immunochemistry based MPT64 antigen detection test has shown improved sensitivity compared to current laboratory tests. The aim of this study ... -
Pre-conception and prenatal alcohol exposure from mothers and fathers drinking and head circumference: results from the Norwegian Mother-Child Study (MoBa)
(Peer reviewed; Journal article, 2016-12-23)Although microcephaly is a feature of Fetal Alcohol Syndrome, it is currently unknown whether low-to-moderate prenatal alcohol exposure affects head circumference. Small magnitude associations reported in observational ... -
Stathmin expression associates with vascular and immune responses in aggressive breast cancer subgroups
(Journal article; Peer reviewed, 2020)Studies indicate that stathmin expression associates with PI3K activation in breast cancer, suggesting stathmin as a marker for targetable patient subgroups. Here we assessed stathmin in relation to tumour proliferation, ... -
The value of histological examination in the diagnosis of tuberculous lymphadenitis in the era of rapid molecular diagnosis
(Journal article; Peer reviewed, 2022)Extrapulmonary tuberculosis often poses a diagnostic challenge. This study aimed to assess the value of histological examination in diagnosing tuberculous lymphadenitis (LNTB) when performed simultaneously with rapid ... -
Vitamin D status and associations with substance use patterns among people with severe substance use disorders in Western Norway
(Journal article; Peer reviewed, 2022)Chronic and harmful substance use is associated with a cluster of harms to health, including micronutrient deficiencies. Maintaining adequate levels of vitamin D is important for musculoskeletal and other aspects of health. ... -
Xpert MTB/RIF ultra for rapid diagnosis of extrapulmonary tuberculosis in a high‑income low‑tuberculosis prevalence setting
(Journal article; Peer reviewed, 2020)The diagnosis of extrapulmonary tuberculosis (EPTB) is often challenging due to paucibacillary nature of the disease. Xpert MTB/RIF Ultra (Ultra) has been developed to improve detection of Mycobacterium tuberculosis complex ...