Department of Clinical Medicine: Recent submissions

Now showing items 21-40 of 2056

    • Longer-term quality of care, effectiveness, and cost-effectiveness of implementing a model of care for osteoarthritis: A cluster-randomized controlled trial 

      Østerås, Nina; Aas, Eline; Moseng, Tuva; van Bodegom-Vos, Leti; Dziedzic, Krysia; Natvig, Bård; Røtterud, Jan H; Vlieland, Thea Vliet; Furnes, Ove Nord; Fenstad, Anne Marie; Hagen, Kåre Birger (Journal article; Peer reviewed, 2024)
      Objective: To assess the quality of care, effectiveness, and cost-effectiveness over 12 months after implementing a structured model of care for hip and knee osteoarthritis (OA) in primary healthcare as compared to usual ...

    • The TP53 Codon 72 Arginine Polymorphism Is Found with Increased TP53 Somatic Mutations in HPV(−) and in an Increased Percentage among HPV(+) Norwegian HNSCC Patients 

      Moe, Svein Erik Emblem; Erland, Fredrik Atteraas; Fromreide, Siren; Lybak, Stein; Brydøy, Marianne; Dongre, Harsh Nitin; Manueldas, Sophia; Costea, Daniela Elena; Vintermyr, Olav Karsten; Aarstad, Hans Jørgen (Journal article; Peer reviewed, 2023-06-26)
      Background: Somatic TP53 mutations are frequent in head and neck squamous cell carcinoma (HNSCC) and are important pathogenic factors. Objective: To study TP53 mutations relative to the presence of human papillomavirus ...

    • Microvascular proliferation is associated with high tumour blood flow by mpMRI and disease progression in primary prostate cancer 

      Børretzen, Astrid; Reisæter, Lars Anders Rokne; Ringheim, Anders; Gravdal, Karsten; Haukaas, Svein Andreas; Fasmer, Kristine Eldevik; Haldorsen, Ingfrid S.; Beisland, Christian; Akslen, Lars Andreas; Halvorsen, Ole Johan (Journal article; Peer reviewed, 2023)
      Active angiogenesis may be assessed by immunohistochemistry using Nestin, a marker of newly formed vessels, combined with Ki67 for proliferating cells. Here, we studied microvascular proliferation by Nestin-Ki67 co-expression ...

    • TP53 mutation and human papilloma virus status as independent prognostic factors in a Norwegian cohort of vulva squamous cell carcinoma 

      Dongre, Harsh Nitin; Elnour, Rammah; Tornaas, Stian; Fromreide, Siren; Thomsen, Liv Cecilie Vestrheim; Kolseth, Ingrid Moss; Nginamau, Elisabeth Sivy; Johannessen, Anne Christine; Vintermyr, Olav Karsten; Costea, Daniela Elena; Bjørge, Line (Journal article; Peer reviewed, 2024)
      Introduction: Vulva squamous cell carcinoma (VSCC) develops through two separate molecular pathways—one involving high-risk human papilloma virus infection (HPV-associated), and the other without HPV infection (HPV-independent) ...

    • Specific neuropsychiatric symptoms are associated with functional decline trajectories in Alzheimer’s disease and Lewy body dementia: a five-year follow-up study 

      Borda, Miguel Germán; Brønnick, Kolbjørn Kallesten; Garcia-Cifuentes, Elkin; Jaramillo-Jiménez, Alberto; Reyes-Ortiz, Carlos; Patricio-Baldera, Jonathan; Sønnesyn, Hogne; Pérez-Zepeda, Mario Ulises; Vik-Mo, Audun Osland; Aarsland, Dag (Journal article; Peer reviewed, 2023-10-17)
      Background: Neuropsychiatric symptoms (NPS) are often overlooked and under-identified symptoms associated with dementia, despite their significant impact on the prognosis of individuals living with the disease. The specific ...

    • A new pathway for penicillin delabeling in Norway 

      Alnæs, Marie Bjørbak; Oppegaard, Oddvar; Kittang, Bård Reiakvam; Lygre, Stein Håkon Låstad; Langeland, Anine Bernhoft; Skodvin, Brita; Bjånes, Tormod Karlsen; Storaas, Torgeir (Journal article; Peer reviewed, 2023)
      Background: Penicillin allergy is self-reported by 3–10% of patients admitted to hospital. The label is wrong in 90% of the cases and has severe health implications. Penicillin-delabeling can reverse the negative effects ...

    • Case Report: Limbic encephalitis following treatment with durvalumab for small-cell lung cancer 

      Moss, Thomas Totland; Stavem, Knut; Aandahl, Astrid; Gløersen, Anne S.; Grønberg, Bjørn Henning; Neumann, Kirill; Vedeler, Christian Alexander; Lundqvist, Christofer (Journal article; Peer reviewed, 2023-10-16)
      Background: Durvalumab is an immune checkpoint Inhibitor (ICIs) that is used in the treatment of malignant tumors, such as lung cancer and melanoma. ICIs are associated with immune-related adverse events including autoimmune ...

    • Orthopaedic surgeons' ability to detect pathologic hip fractures: review of 1484 fractures reported to the Norwegian Hip Fracture Register 

      Sund, Anders; Dybvik, Eva Hansen; Gjertsen, Jan-Erik (Journal article; Peer reviewed, 2023-11-04)
      Background: The proximal femur is the most common location of metastases in the appendicular skeleton. Data on pathologic hip fractures, however, are sparse despite it is the most frequently operated pathologic fracture. ...

    • Cognitive assessment in the early stages of multiple sclerosis : the importance of screening and management of cognitive impairment 

      Skorve, Ellen Danielsen (Doctoral thesis, 2024-04-19)
      Bakgrunn: Kognitiv svekkelse er et vanlig symptom hos pasienter med multippel sklerose (MS), med potentielt stor innvirkning på livskvalitet, yrkesdeltagelse og sosialt liv. Dette kan oppstå i alle stadier og alle subtyper ...

    • Use and non-use of antipsychotics and other psychotropic drugs in schizophrenia 

      Strømme, Maria Fagerbakke (Doctoral thesis, 2022-06-08)
      Background: Little is known about health-related outcomes for patients with schizophrenia when comparing periods with use and non-use of antipsychotic drugs in a real-life setting. Current evidence is also limited for the ...

    • Validation of forearm fracture diagnoses in administrative patient registers 

      Omsland, Tone Kristin; Solberg, Lene Bergendal; Bjørnerem, Åshild Marit; Borgen, Tove Tveitan; Andreasen, Camilla; Wisløff, Torbjørn; Hagen, Gunhild; Basso, Trude; Gjertsen, Jan-Erik; Apalset, Ellen Margrete; Figved, Wender; Stutzer, Jens-Meinhard; Nissen, Frida Igland; Hansen, Ann Kristin; Joakimsen, Ragnar Martin; Figari, Elisa; Peel, Geoffrey; Rashid, Ali A.; Khoshkhabari, Jashar; Eriksen, Erik Fink; Nordsletten, Lars; Frihagen, Frede; Dahl, Cecilie (Journal article; Peer reviewed, 2023)
      Summary: The validity of forearm fracture diagnoses recorded in five Norwegian hospitals was investigated using image reports and medical records as gold standard. A relatively high completeness and correctness of the ...

    • Neurofilament and Brain Atrophy and Their Association with Cognition in Multiple Sclerosis: A 10-Year Follow-Up Study 

      Bhan, Alok; Jacobsen, Cecilie; Dalen, Ingvild; Alves, Guido Werner; Bergsland, Niels; Myhr, Kjell-Morten; Zetterberg, Henrik; Zivadinov, Robert; Farbu, Elisabeth (Journal article; Peer reviewed, 2023)
      Introduction. Cognitive impairment is an important contributor to disability in multiple sclerosis (MS). Disconnection of neuronal circuits due to axonal injury is probably an important underlying mechanism for this ...

    • COL11A1 is associated with developmental dysplasia of the hip and secondary osteoarthritis in the HUNT study 

      Jacobsen, Kaya Kvarme; Børte, Sigrid; Laborie, Lene Bjerke; Kristiansen, Hege; Schäfer, Annette; Gundersen, Trude; Zayats, Tetyana; Winsvold, Bendik Kristoffer Slagsvold; Karen, Rosendahl; Martinsen, Amy; Skogholt, Anne Heidi; Brumpton, Ben Michael; Willer, Cristen J; Fors, Egil Andreas; Kristoffersen, Espen Saxhaug; Heuch, Ingrid; Mundal, Ingunn Pernille; Zwart, John Anker Henrik; Nielsen, Jonas B.; Storheim, Kjersti; Hagen, Knut; Nilsen, Kristian Bernhard; Hveem, Kristian; Fritsche, Lars G; Thomas, Laurent Francois; Pedersen, Linda Margareth; Gabrielsen, Maiken Elvestad; Lie, Marie U.; Stensland, Synne; Zhou, Wei (Journal article; Peer reviewed, 2024)
      Objective: Developmental dysplasia of the hip (DDH) is a congenital condition affecting 2-3% of all infants. DDH increases the risk of osteoarthritis, is the cause of 30% of all total hip arthroplasties (THAs) in adults ...

    • Kidney Dysfunction and Pathology in the Setting of Hemophagocytic Lymphohistiocytosis 

      Sekulic, Miroslav; Batal, Ibrahim; Kudose, Satoru; Santoriello, Dominick; Stokes, M. Barry; Jim, Belinda; Marti, Hans Peter; Eikrem, Øystein Solberg; Radhakrishnan, Jai; D'Agati, Vivette D.; Markowitz, Glen S. (Journal article; Peer reviewed, 2023)
      Introduction Hemophagocytic lymphohistiocytosis (HLH) is a clinicopathologic syndrome produced by dysregulated activation of the immune system. Acute kidney injury (AKI) and proteinuria have been infrequently described ...

    • The Delta III and Delta Xtend reverse shoulder arthroplasty. Risk of revision and failure mechanisms: a report on 3,650 cases from the Norwegian Arthroplasty Register 1994-2021 

      Hole, Randi Margrete; Fenstad, Anne Marie; Gjertsen, Jan-Erik; Hallan, Geir; Furnes, Ove Nord (Journal article; Peer reviewed, 2024)
      Background The Delta reverse shoulder arthroplasty (RSA) is commonly used worldwide and is the most frequently used RSA in Norway. The aim of this registry-based study was to report 10- and 20-year implant survival, ...

    • The association of dietary patterns with muscle mass and strength in old age: The Hordaland Health Study 

      Sabir, Zoya; Dierkes, Jutta; Hjartåker, Anette; Rosendahl-Riise, Hanne (Journal article; Peer reviewed, 2023)
      Purpose: The single nutrient approach in nutrition research lacks the ability to account for synergistic relationships between dietary components. Current evidence suggests that diet quality, reflecting overall dietary ...

    • Cytokine Patterns as Predictors of Antibiotic Treatment Effect in Chronic Low Back Pain with Modic Changes: Subgroup Analyses of a Randomized Trial (AIM Study) 

      Bråten, Lars Christian Haugli; Gjefsen, Elisabeth; Gervin, Kristina; Pripp, Are Hugo; Skouen, Jan Sture; Schistad, Elina Iordanova; Pedersen, Linda Margareth; Wigemyr, Monica; Selmer, Kaja Kristine; Dalsbotten Aass, Hans Christian; Goll, Guro Løvik; Brox, Jens Ivar; Espeland, Ansgar; Grøvle, Lars; Zwart, John Anker Henrik; Storheim, Kjersti (Journal article; Peer reviewed, 2023)
      Objective: Randomized trials testing the effect of antibiotics for chronic low back pain (LBP) with vertebral bone marrow changes on MRI (Modic changes) report inconsistent results. A proposed explanation is subgroups with ...

    • Diabetisk ketoacidose ved bruk av SGLT2-hemmer – en pasientserie 

      Lejlic, Selma; Holmaas, Gunhild; Løvås, Kristian; Ueland, Grethe Åstrøm (Journal article; Peer reviewed, 2023)
      Bakgrunn: Hemmere av natriumglukose-kotransportør 2 (SGLT2-hemmere) benyttes i økende grad ved diabetes type 2. Resultater fra tidligere studier tyder på en økt forekomst av diabetisk ketoacidose ved bruk av disse ...

    • Long-term follow-up of IgA nephropathy: clinicopathological features and predictors of outcomes 

      Haaskjold, Yngvar Lunde; Lura, Njål; Bjørneklett, Rune Oskar; Bostad, Lars Sigurd; Knoop, Thomas; Bostad, Leif Henry (Journal article; Peer reviewed, 2023)
      Background: The establishment of the Oxford classification and newly developed prediction models have improved the prognostic information for immunoglobulin A nephropathy (IgAN). Considering new treatment options, optimizing ...

    • Complications and device failures associated with urolift: Findings from the MAUDE database 

      Jones, Charles Patrick W.; Somani, Bhaskar K; Tzelves, Lazaros; Haugland, Julie Nøss; Moen, Christian Arvei; Honoré, Alfred; Beisland, Christian (Journal article; Peer reviewed, 2023)
      Introduction: Urolift is an established intervention for symptoms of bladder outflow obstruction caused by benign prostate enlargement. Reported advantages include its minimally invasive profile, short learning curve and ...