Department of Clinical Medicine: Recent submissions

Now showing items 1-20 of 2029

    • Orthopaedic surgeons' ability to detect pathologic hip fractures: review of 1484 fractures reported to the Norwegian Hip Fracture Register 

      Sund, Anders; Dybvik, Eva Hansen; Gjertsen, Jan-Erik (Journal article; Peer reviewed, 2023-11-04)
      Background: The proximal femur is the most common location of metastases in the appendicular skeleton. Data on pathologic hip fractures, however, are sparse despite it is the most frequently operated pathologic fracture. ...

    • Cognitive assessment in the early stages of multiple sclerosis : the importance of screening and management of cognitive impairment 

      Skorve, Ellen Danielsen (Doctoral thesis, 2024-04-19)
      Bakgrunn: Kognitiv svekkelse er et vanlig symptom hos pasienter med multippel sklerose (MS), med potentielt stor innvirkning på livskvalitet, yrkesdeltagelse og sosialt liv. Dette kan oppstå i alle stadier og alle subtyper ...

    • Use and non-use of antipsychotics and other psychotropic drugs in schizophrenia 

      Strømme, Maria Fagerbakke (Doctoral thesis, 2022-06-08)
      Background: Little is known about health-related outcomes for patients with schizophrenia when comparing periods with use and non-use of antipsychotic drugs in a real-life setting. Current evidence is also limited for the ...

    • Validation of forearm fracture diagnoses in administrative patient registers 

      Omsland, Tone Kristin; Solberg, Lene Bergendal; Bjørnerem, Åshild Marit; Borgen, Tove Tveitan; Andreasen, Camilla; Wisløff, Torbjørn; Hagen, Gunhild; Basso, Trude; Gjertsen, Jan-Erik; Apalset, Ellen Margrete; Figved, Wender; Stutzer, Jens-Meinhard; Nissen, Frida Igland; Hansen, Ann Kristin; Joakimsen, Ragnar Martin; Figari, Elisa; Peel, Geoffrey; Rashid, Ali A.; Khoshkhabari, Jashar; Eriksen, Erik Fink; Nordsletten, Lars; Frihagen, Frede; Dahl, Cecilie (Journal article; Peer reviewed, 2023)
      Summary: The validity of forearm fracture diagnoses recorded in five Norwegian hospitals was investigated using image reports and medical records as gold standard. A relatively high completeness and correctness of the ...

    • Neurofilament and Brain Atrophy and Their Association with Cognition in Multiple Sclerosis: A 10-Year Follow-Up Study 

      Bhan, Alok; Jacobsen, Cecilie; Dalen, Ingvild; Alves, Guido Werner; Bergsland, Niels; Myhr, Kjell-Morten; Zetterberg, Henrik; Zivadinov, Robert; Farbu, Elisabeth (Journal article; Peer reviewed, 2023)
      Introduction. Cognitive impairment is an important contributor to disability in multiple sclerosis (MS). Disconnection of neuronal circuits due to axonal injury is probably an important underlying mechanism for this ...

    • COL11A1 is associated with developmental dysplasia of the hip and secondary osteoarthritis in the HUNT study 

      Jacobsen, Kaya Kvarme; Børte, Sigrid; Laborie, Lene Bjerke; Kristiansen, Hege; Schäfer, Annette; Gundersen, Trude; Zayats, Tetyana; Winsvold, Bendik Kristoffer Slagsvold; Karen, Rosendahl; Martinsen, Amy; Skogholt, Anne Heidi; Brumpton, Ben Michael; Willer, Cristen J; Fors, Egil Andreas; Kristoffersen, Espen Saxhaug; Heuch, Ingrid; Mundal, Ingunn Pernille; Zwart, John Anker Henrik; Nielsen, Jonas B.; Storheim, Kjersti; Hagen, Knut; Nilsen, Kristian Bernhard; Hveem, Kristian; Fritsche, Lars G; Thomas, Laurent Francois; Pedersen, Linda Margareth; Gabrielsen, Maiken Elvestad; Lie, Marie U.; Stensland, Synne; Zhou, Wei (Journal article; Peer reviewed, 2024)
      Objective: Developmental dysplasia of the hip (DDH) is a congenital condition affecting 2-3% of all infants. DDH increases the risk of osteoarthritis, is the cause of 30% of all total hip arthroplasties (THAs) in adults ...

    • Kidney Dysfunction and Pathology in the Setting of Hemophagocytic Lymphohistiocytosis 

      Sekulic, Miroslav; Batal, Ibrahim; Kudose, Satoru; Santoriello, Dominick; Stokes, M. Barry; Jim, Belinda; Marti, Hans Peter; Eikrem, Øystein Solberg; Radhakrishnan, Jai; D'Agati, Vivette D.; Markowitz, Glen S. (Journal article; Peer reviewed, 2023)
      Introduction Hemophagocytic lymphohistiocytosis (HLH) is a clinicopathologic syndrome produced by dysregulated activation of the immune system. Acute kidney injury (AKI) and proteinuria have been infrequently described ...

    • The Delta III and Delta Xtend reverse shoulder arthroplasty. Risk of revision and failure mechanisms: a report on 3,650 cases from the Norwegian Arthroplasty Register 1994-2021 

      Hole, Randi Margrete; Fenstad, Anne Marie; Gjertsen, Jan-Erik; Hallan, Geir; Furnes, Ove Nord (Journal article; Peer reviewed, 2024)
      Background The Delta reverse shoulder arthroplasty (RSA) is commonly used worldwide and is the most frequently used RSA in Norway. The aim of this registry-based study was to report 10- and 20-year implant survival, ...

    • The association of dietary patterns with muscle mass and strength in old age: The Hordaland Health Study 

      Sabir, Zoya; Dierkes, Jutta; Hjartåker, Anette; Rosendahl-Riise, Hanne (Journal article; Peer reviewed, 2023)
      Purpose: The single nutrient approach in nutrition research lacks the ability to account for synergistic relationships between dietary components. Current evidence suggests that diet quality, reflecting overall dietary ...

    • Cytokine Patterns as Predictors of Antibiotic Treatment Effect in Chronic Low Back Pain with Modic Changes: Subgroup Analyses of a Randomized Trial (AIM Study) 

      Bråten, Lars Christian Haugli; Gjefsen, Elisabeth; Gervin, Kristina; Pripp, Are Hugo; Skouen, Jan Sture; Schistad, Elina Iordanova; Pedersen, Linda Margareth; Wigemyr, Monica; Selmer, Kaja Kristine; Dalsbotten Aass, Hans Christian; Goll, Guro Løvik; Brox, Jens Ivar; Espeland, Ansgar; Grøvle, Lars; Zwart, John Anker Henrik; Storheim, Kjersti (Journal article; Peer reviewed, 2023)
      Objective: Randomized trials testing the effect of antibiotics for chronic low back pain (LBP) with vertebral bone marrow changes on MRI (Modic changes) report inconsistent results. A proposed explanation is subgroups with ...

    • Diabetisk ketoacidose ved bruk av SGLT2-hemmer – en pasientserie 

      Lejlic, Selma; Holmaas, Gunhild; Løvås, Kristian; Ueland, Grethe Åstrøm (Journal article; Peer reviewed, 2023)
      Bakgrunn: Hemmere av natriumglukose-kotransportør 2 (SGLT2-hemmere) benyttes i økende grad ved diabetes type 2. Resultater fra tidligere studier tyder på en økt forekomst av diabetisk ketoacidose ved bruk av disse ...

    • Long-term follow-up of IgA nephropathy: clinicopathological features and predictors of outcomes 

      Haaskjold, Yngvar Lunde; Lura, Njål; Bjørneklett, Rune Oskar; Bostad, Lars Sigurd; Knoop, Thomas; Bostad, Leif Henry (Journal article; Peer reviewed, 2023)
      Background: The establishment of the Oxford classification and newly developed prediction models have improved the prognostic information for immunoglobulin A nephropathy (IgAN). Considering new treatment options, optimizing ...

    • Complications and device failures associated with urolift: Findings from the MAUDE database 

      Jones, Charles Patrick W.; Somani, Bhaskar K; Tzelves, Lazaros; Haugland, Julie Nøss; Moen, Christian Arvei; Honoré, Alfred; Beisland, Christian (Journal article; Peer reviewed, 2023)
      Introduction: Urolift is an established intervention for symptoms of bladder outflow obstruction caused by benign prostate enlargement. Reported advantages include its minimally invasive profile, short learning curve and ...

    • Does choice of bearings influence the survival of cement-less total hip arthroplasty in patients aged 20–55 years? Comparison of 21,594 patients reported to the Nordic Arthroplasty Register Association dataset 2005–2017 

      Mikkelsen, Rasmus Tyrsted; Overgaard, Søren; Pedersen, Alma B.; Kärrholm, Johan; Rolfson, Ola; Fenstad, Anne Marie; Furnes, Ove Nord; Hallan, Geir; Mäkelä, Keijo; Eskelinen, Antti; Varnum, Claus (Journal article; Peer reviewed, 2023)
      Background and purpose: The bearings with the best survivorship for young patients with total hip arthroplasty (THA) should be identified. We compared hazard ratios (HR) of revision of primary stemmed cementless THAs with ...

    • Increasing the transplant dose and repeating faecal microbiota transplantation results in the responses of male patients with IBS reaching those of females 

      El-Salhy, Magdhy; Gilja, Odd Helge; Hatlebakk, Jan Gunnar (Journal article; Peer reviewed, 2023)
      Background Faecal microbiota transplantation (FMT) performed with a proper protocol is a safe treatment for IBS that has high efficacy and durable effects. Females have been reported to respond better than males to FMT. ...

    • Increasing age of multiple sclerosis onset from 1920 to 2022: a population-based study 

      Habbestad, Andrea Kyvik; Willumsen, Johannes Sverre; Aarseth, Jan Harald; Grytten, Nina; Midgard, Rune; Wergeland, Stig; Myhr, Kjell-Morten; Torkildsen, Øivind (Journal article; Peer reviewed, 2023)
      Objective To study the age at onset of relapsing–remitting multiple sclerosis (RRMS) during the past century. Methods This is a population-based cohort study of persons diagnosed with RRMS in Hordaland, Møre, and ...

    • Reuniting philosophy and science to advance cancer research 

      Pradeu, Thomas; Daignan-Fornier, Bertrand; Ewald, Andrew; Germain, Pierre-Luc; Okasha, Samir; Plutynski, Anya; Benzekry, Sébastien; Bertolaso, Marta; Bissell, Mina; Brown, Joel S.; Chin-Yee, Benjamin; Chin-Yee, Ian; Clevers, Hans; Cognet, Laurent; Darrason, Marie; Farge, Emmanuel; Feunteun, Jean; Galon, Jérôme; Giroux, Elodie; Green, Sara; Gross, Fridolin; Jaulin, Fanny; Knight, Rob; Laconi, Ezio; Larmonier, Nicolas; Maley, Carlo; Mantovani, Alberto; Moreau, Violaine; Nassoy, Pierre; Rondeau, Elena; Santamaria, David; Sawai, Catherine M.; Seluanov, Andrei; Sepich-Poore, Gregory D.; Sisirak, Vanja; Solary, Eric; Yvonnet, Sarah; Laplane, Lucie (Journal article; Peer reviewed, 2023)
      Cancers rely on multiple, heterogeneous processes at different scales, pertaining to many biomedical fields. Therefore, understanding cancer is necessarily an interdisciplinary task that requires placing specialised ...

    • Cognitive behavior therapy for adult depressive disorders in routine clinical care: A systematic review and meta-analysis 

      Öst, Lars Gøran; Enebrink, Pia; Finnes, Anna; Ghaderi, Ata; Havnen, Audun; Kvale, Gerd; Salomonsson, Sigrid; Wergeland, Gro Janne Henningsen (Journal article; Peer reviewed, 2023)
      Background Different cognitive behavioral therapies (CBT) have strong research support for treatment of adult depressive disorders (DD). Given the scarcity of knowledge about the performance of CBT in routine clinical ...

    • Augmented reality versus standard tests to assess cognition and function in early Alzheimer’s disease 

      Muurling, Marijn; de Boer, Casper; Vairavan, Srinivasan; Harms, Robbert L.; Chadha, Antonella Santuccione; Tarnanas, Ioannis; Luis, Estefania Vilarino; Religa, Dorota; Gjestsen, Martha Therese; Galluzzi, Samantha; Ibarria Sala, Marta; Koychev, Ivan; Hausner, Lucrezia; Gkioka, Mara; Aarsland, Dag; Visser, Pieter Jelle; Brem, Anna-Katharine (Journal article; Peer reviewed, 2023)
      Augmented reality (AR) apps, in which the virtual and real world are combined, can recreate instrumental activities of daily living (IADL) and are therefore promising to measure cognition needed for IADL in early Alzheimer’s ...

    • Longitudinal cerebrospinal fluid measurements show glial hypo- and hyperactivation in predementia Alzheimer’s disease 

      Nordengen, Kaja; Kirsebom, Bjørn-Eivind Seljelid; Richter, Grit; Pålhaugen, Lene; Gisladottir, Berglind; Siafarikas, Nikias Ioannis; Nakling, Arne Exner; Rongve, Arvid; Bråthen, Geir; Grøntvedt, Gøril Rolfseng; Gonzalez, Fernando; Waterloo, Knut; Sharma, Kulbhushan; Karikari, Thomas; Vromen, Eleonora M.; Tijms, Betty M.; Visser, Pieter J.; Selnes, Per; Kramberger, Milicia G.; Winblad, Bengt; Blennow, Kaj; Fladby, Tormod (Journal article; Peer reviewed, 2023)
      Background Brain innate immune activation is associated with Alzheimer’s disease (AD), but degrees of activation may vary between disease stages. Thus, brain innate immune activation must be assessed in longitudinal ...