• Diabetes and Osteoarthritis: Exploring the Interactions and Therapeutic Implications of Insulin, Metformin, and GLP-1-Based Interventions 

  Halabitska, Iryna; Babinets, Liliia; Oksenych, Valentyn; Kamyshnyi, Oleksandr (Journal article; Peer reviewed, 2024-07-23)

  Diabetes mellitus (DM) and osteoarthritis (OA) are prevalent chronic conditions with shared pathophysiological links, including inflammation and metabolic dysregulation. This study investigates the potential impact of ...

• Development and Optimization of Nasal Composition of a Neuroprotective Agent for Use in Neonatology after Prenatal Hypoxia 

  Belenichev, Igor; Aliyeva, Olena; Burlaka, Bogdan; Burlaka, Kristina; Kuchkovskyi, Oleh; Savchenko, Dmytro; Oksenych, Valentyn; Kamyshnyi, Oleksandr (Journal article; Peer reviewed, 2024-07-26)

  The intranasal route of drug administration is characterized by high bioavailability and is considered promising for rapid delivery of drugs with systemic action to the central nervous system (CNS), bypassing the blood-brain ...

• Dysregulation of miR-223, miR-146a, and miR-193a Expression Profile in Acute and Chronic Phases of Experimental Autoimmune Encephalomyelitis in C57BL/6 Mice 

  Gharibi, Saba; Moghimi, Bahram; Mahmoudi, Mohammad Bagher; Shahvazian, Ensieh; Yazd, Ehsan Farashahi; Yadegari, Maryam; Tahoori, Mohammad Taher; Yazdanpanah, Esmaeil; Haghmorad, Dariush; Oksenych, Valentyn (Journal article; Peer reviewed, 2024-09-06)

  Multiple sclerosis (MS) is a chronic autoimmune disease with an unknown etiology. The purpose of this research was to assess miR-223, miR-146a, and miR-193a in acute and chronic phases of experimental autoimmune encephalomyelitis ...

• Genomic insight into COVID-19 severity in MAFLD patients: a single-center prospective cohort study 

  Buchynskyi, Mykhailo; Oksenych, Valentyn; Kamyshna, Iryna; Budarna, Olena; Halabitska, Iryna; Petakh, Pavlo; Kamyshnyi, Oleksandr (Journal article; Peer reviewed, 2024-09-04)

  This study investigated the influence of single nucleotide polymorphisms (SNPs) in genes associated with the interferon pathway (IFNAR2 rs2236757), antiviral response (OAS1 rs10774671, OAS3 rs10735079), and viral entry ...

• Beta-Blockers of Different Generations: Features of Influence on the Disturbances of Myocardial Energy Metabolism in Doxorubicin-Induced Chronic Heart Failure in Rats 

  Belenichev, Igor; Goncharov, Olexiy; Bukhtiyarova, Nina; Kuchkovskyi, Oleh; Ryzhenko, Victor; Makyeyeva, Lyudmyla; Oksenych, Valentyn; Kamyshnyi, Oleksandr (Journal article; Peer reviewed, 2024-08-28)

  Beta-blockers are first-line drugs in the treatment of chronic heart failure (CHF). However, there is no consensus on the specific effects of the beta-blockers of the I-III generation on energy metabolism in CHF. The aim ...

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