Blar i Bergen Open Research Archive på forfatter "Thomassen, Lars"
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Persistent microembolic signals in the cerebral circulation on transcranial Doppler after intravenous sulfur hexafluoride microbubble infusion
Aarli, Sander Johan; Novotny, Vojtech; Thomassen, Lars; Kvistad, Christopher Elnan; Logallo, Nicola; Fromm, Annette (Peer reviewed; Journal article, 2020)Background and purpose: Microembolic signals (MES) are detectable by transcranial Doppler monitoring and associated with increased risk of first or recurrent ischemic stroke. MES detection can also illuminate stroke etiology ... -
A pragmatic approach to sonothrombolysis in acute ischaemic stroke: The Norwegian randomised controlled sonothrombolysis in acute stroke study (NOR-SASS)
Nacu, Aliona; Kvistad, Christopher Elnan; Logallo, Nicola; Næss, Halvor; Waje-Andreassen, Ulrike; Aamodt, Anne Hege; Solhoff, Ragnar; Lund, Christian; Tobro, Håkon; Rønning, Ole Morten; Salvesen, Rolf; Idicula, Titto; Thomassen, Lars (Peer reviewed; Journal article, 2015-07-11)Background: Ultrasound accelerates thrombolysis with tPA (sonothrombolysis). Ultrasound in the absence of tPA also accelerates clot break-up (sonolysis). Adding intravenous gaseous microbubbles may potentiate the effect ... -
Prevalence of atherosclerosis and association with 5-year outcome: The Norwegian Stroke in the Young Study
Nawaz, Beenish; Fromm, Annette; Øygarden, Halvor; Eide, Geir E; Saeed, Sahrai; Meijer, Rudy; Bots, Michiel L; Sand, Kristin M; Thomassen, Lars; Næss, Halvor; Waje-Andreassen, Ulrike (Journal article; Peer reviewed, 2021)Objectives: We studied the prevalence of atherosclerosis among ischaemic stroke patients ≤60 years and controls at the time of the index stroke, and its association with occurrence of new cardiovascular events (CVEs) and ... -
Recurrent ischemic stroke: Incidence, predictors, and impact on mortality
Khanevski, Andrej; Bjerkreim, Anna Therese; Novotny, Vojtech; Næss, Halvor; Thomassen, Lars; Logallo, Nicola; Kvistad, Christopher Elnan (Peer reviewed; Journal article, 2019)Background and purpose: Recurrent ischemic stroke (IS) or TIA is frequent with a considerable variation in incidence and mortality across populations. Current data on stroke recurrence and mortality are useful to examine ... -
Risk factors and their impact on carotid intima-media thickness in young and middle-aged ischemic stroke patients and controls: The Norwegian Stroke in the Young Study
Fromm, Annette; Haaland, Øystein Ariansen; Næss, Halvor; Thomassen, Lars; Waje-Andreassen, Ulrike (Peer reviewed; Journal article, 2014-03-26)Background: Vascular morbidity and mortality due to cardiovascular disease (CVD) are high after ischemic stroke at a young age. Data on carotid intima-media thickness (cIMT) as marker of atherosclerosis are scarce for young ... -
Serum uri acid: neuroprotection in thrombolysis. The Bergen NORSTROKE study
Logallo, Nicola; Næss, Halvor; Idicula, Titto T.; Brøgger, Jan C.; Waje-Andreassen, Ulrike; Thomassen, Lars (Peer reviewed; Journal article, 2011-09-25)Background: A possible synergic role of serum uric acid (SUA) with thrombolytic therapies is controversial and needs further investigations. We therefore evaluated association of admission SUA with clinical improvement and ... -
Stroke patients’ knowledge about cardiovascular family history – the Norwegian Stroke in the Young Study (NOR-SYS).
Øygarden, Halvor; Fromm, Annette; Sand, Kristin Modalsli; Eide, Geir Egil; Thomassen, Lars; Næss, Halvor; Waje-Andreassen, Ulrike (Peer reviewed; Journal article, 2015-03-12)Background: Family history (FH) is a risk factor for cardiovascular disease, especially coronary artery disease (CAD). The impact on risk of stroke is less clear. This study investigated young and middle-aged ischemic ... -
Tenecteplase, 0.4 mg/kg, in Moderate and Severe Acute Ischemic Stroke: A Pooled Analysis of NOR-TEST and NOR-TEST 2A
Novotny, Vojtech; Kvistad, Christopher Elnan; Næss, Halvor; Logallo, Nicola; Fromm, Annette; Khanevski, Andrej; Thomassen, Lars (Journal article; Peer reviewed, 2023)Background: The optimal dose of tenecteplase in acute ischemic stroke remains to be defined. We present a pooled analysis of the 2 NOR‐TESTs (Norwegian Tenecteplase Stroke Trials) exploring the efficacy and safety of ... -
Time course of cerebrovascular reactivity in patients treated for unruptured intracranial aneurysms: A one-year transcranial Doppler and acetazolamide follow-up study
Bøthun, Marianne Lundervik; Haaland, Øystein Ariansen; Logallo, Nicola; Svendsen, Frode; Thomassen, Lars; Helland, Christian Andre (Peer reviewed; Journal article, 2018-04-26)Background. Cerebrovascular reactivity (CVR) is ofen impaired in the early phase afer aneurysmal subarachnoid hemorrhage. Tere is, however, little knowledge about the time course of CVR in patients treated for unruptured ... -
Vascular risk factors and staging of atherosclerosis in patients and controls: The Norwegian Stroke in the Young Study
Nawaz, Beenish; Fromm, Annette; Øygarden, Halvor; Eide, Geir Egil; Saeed, Sahrai; Meijer, Rudy; Bots, Michiel L; Sand, Kristin Modalsli; Thomassen, Lars; Næss, Halvor; Waje-Andreassen, Ulrike (Journal article; Peer reviewed, 2022)Objectives: We studied the prevalence of vascular risk factors (RFs) among 385 ischaemic stroke patients ⩽60 years and 260 controls, and their association with atherosclerosis in seven vascular areas. Methods: History ... -
Young ischaemic stroke incidence and demographic characteristics - The Norwegian stroke in the young study - A three-generation research program
Nawaz, Beenish; Eide, Geir Egil; Fromm, Annette; Øygarden, Halvor; Sand, Kristin Modalsli; Thomassen, Lars; Næss, Halvor; Waje-Andreassen, Ulrike (Journal article; Peer reviewed, 2019)Introduction: Norwegian Stroke in the Young Study (NOR-SYS) is a three-generation research program of young ischaemic stroke. In this study, we assessed ischaemic stroke incidence, education and work status among young ...