• Regulation and quantification of cellular mitochondrial morphology and content 

      Tronstad, Karl Johan; Nooteboom, Marco; Hodneland, Linn I.; Nikolaisen, Julie; Sokolewicz, Maciek; Grefte, Sander; Pettersen, Ina Katrine Nitschke; Dyrstad, Sissel Elisabeth; Hoel, Fredrik; Willems, Peter H.G.M.; Koopman, Werner J.H. (Peer reviewed; Journal article, 2014)
      Mitochondria play a key role in signal transduction, redox homeostasis and cell survival, which extends far beyond their classical functioning in ATP production and energy metabolism. In living cells, mitochondrial content ...
    • Upregulated PDK4 expression is a sensitive marker of increased fatty acid oxidation 

      Pettersen, Ina Katrine Nitschke; Tusubira, Deusdedit; Ashrafi, Hanan; Dyrstad, Sissel Elisabeth; Hansen, Lena; Liu, Xiao-Zheng; Hodneland, Linn I.; Løvsletten, Nils Gunnar; Berge, Kjetil; Wergedahl, Hege; Bjørndal, Bodil; Fluge, Øystein; Bruland, Ove; Rustan, Arild; Halberg, Nils; Røsland, Gro Vatne; Berge, Rolf Kristian; Tronstad, Karl Johan (Peer reviewed; Journal article, 2019)
      Fatty acid oxidation is a central fueling pathway for mitochondrial ATP production. Regulation occurs through multiple nutrient- and energy-sensitive molecular mechanisms. We explored if upregulated mRNA expression of the ...