Blar i Bergen Open Research Archive på forfatter "Langeland, Nina"
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Nosocomial outbreak of neonatal Salmonella enterica serotype Enteritidis meningitis in a rural hospital in northern Tanzania
Vaagland, Hogne; Blomberg, Bjørn; Krüger, Carsten; Naman, Naftali; Jureen, Roland; Langeland, Nina (Peer reviewed; Journal article, 2007-09-14)Background: Clinicians at Haydom Lutheran Hospital, a rural hospital in northern Tanzania noted an unusually high case-fatality rate of pediatric meningitis and suspected an outbreak of an unknown agent or an organism ... -
A novel fibrosis index comprising a non-cholesterol sterol accurately predicts HCV-related liver cirrhosis
Ydreborg, Magdalena; Lisovskaja, Vera; Lagging, Martin; Christensen, Peer Brehm; Langeland, Nina; Buhl, Mads Rauning; Pedersen, Court; Mørch, Kristine; Wejstål, Rune; Norkrans, Gunnar; Lindh, Magnus; Färkkilä, Martti; Westin, Johan (Peer reviewed; Journal article, 2014-04-03)Diagnosis of liver cirrhosis is essential in the management of chronic hepatitis C virus (HCV) infection. Liver biopsy is invasive and thus entails a risk of complications as well as a potential risk of sampling error. ... -
A novel, single-amplification PCR targeting mitochondrial genome highly sensitive and specific in diagnosing malaria among returned travellers in Bergen, Norway
Haanshuus, Christel Gill; Mohn, Stein Christian; Mørch, Kristine; Langeland, Nina; Blomberg, Bjørn; Hanevik, Kurt (Peer reviewed; Journal article, 2013-01-22)Background: Nested PCR is a commonly used technique in diagnosis of malaria owing to its high sensitivity and specificity. However, it is time-consuming, open to considerable risk of contamination and has low cost-efficiency. ... -
A novel, single-amplification PCR targeting mitochondrial genome highly sensitive and specific in diagnosing malaria among returned travellers in Bergen, Norway
Haanshuus, Christel Gill; Mohn, Stein Christian; Mørch, Kristine; Langeland, Nina; Blomberg, Bjørn; Hanevik, Kurt (Peer reviewed; Journal article, 2013-01-22)Background: Nested PCR is a commonly used technique in diagnosis of malaria owing to its high sensitivity and specificity. However, it is time-consuming, open to considerable risk of contamination and has low cost-efficiency. ... -
Oocyst Shedding Dynamics in Children with Cryptosporidiosis: a Prospective Clinical Case Series in Ethiopia
Johansen, Øystein Haarklau; Abdissa, Alemseged; Bjørang, Ola; Zangenberg, Mike; Sharew, Bizuwarek; Alemu, Yonas; Moyo, Sabrina John; Mekonnen, Zeleke; Langeland, Nina; Robertson, Lucy; Hanevik, Kurt (Journal article; Peer reviewed, 2022)Knowledge on the duration of Cryptosporidium oocyst shedding, and how shedding may be affected by subtypes and clinical parameters, is limited. Reduced transmission may be a secondary benefit of cryptosporidiosis treatment ... -
PCR targeting Plasmodium mitochondrial genome of DNA extracted from dried blood on filter paper compared to whole blood
Strøm, Gro Elizabeth Ann; Moyo, Sabrina John; Fataki, Maulidi; Langeland, Nina; Blomberg, Bjørn (Peer reviewed; Journal article, 2014-04-07)Background: Monitoring mortality and morbidity attributable to malaria is paramount to achieve elimination of malaria. Diagnosis of malaria is challenging and PCR is a reliable method for identifying malaria with high ... -
Perceived food intolerance and irritable bowel syndrome in a population 3 years after a giardiasis-outbreak: a historical cohort study
Litleskare, Sverre; Wensaas, Knut-Arne; Eide, Geir Egil; Hanevik, Kurt; Kahrs, Gudrun E; Langeland, Nina; Rørtveit, Guri (Peer reviewed; Journal article, 2015-11-19)Background: Studies have shown an increased prevalence of irritable bowel syndrome (IBS) after acute gastroenteritis. Food as a precipitating and perpetuating factor in IBS has gained recent interest, but food intolerance ... -
Performance and operational feasibility of two diagnostic tests for cryptosporidiosis in children (CRYPTO-POC): a clinical, prospective, diagnostic accuracy study
Johansen, Øystein Haarklau; Abdissa, Alemseged; Zangenberg, Mike; Mekonnen, Zeleke; Eshetu, Beza; Bjørang, Ola; Alemu, Yonas; Sharew, Bizuwarek; Langeland, Nina; Robertson, Lucy; Hanevik, Kurt (Journal article; Peer reviewed, 2021)Background: Cryptosporidiosis is a common cause of diarrhoea in young children (aged younger than 24 months) in low-resource settings but is currently challenging to diagnose. Light-emitting diode fluorescence microscopy ... -
The Performances of Three Commercially Available Assays for the Detection of SARS‐CoV‐2 Antibodies at Different Time Points Following SARS‐CoV‐2 Infection
Syre, Heidi; Obreque, Marius Eduardo Brå; Dalen, Ingvild; Riis, Åse Garløv; Berg, Åse; Löhr, Iren Høyland; Sundal, Jon; Kleppe, Lars Kåre Selland; Vadla, May Sissel; Lenning, Ole Bernt; Olofsson, Jan Stefan; Mohn, Kristin Greve-Isdahl; Tøndel, Camilla; Blomberg, Bjørn; Trieu, Mai Chi; Langeland, Nina; Cox, Rebecca Jane (Journal article; Peer reviewed, 2022)The aim of this study was to evaluate the performances of three commercially available antibody assays for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies at different time points ... -
Plasma levels of interleukin 27 in falciparum malaria is increased independently of co-infection with HIV: potential immune-regulatory role during malaria
Otterdal, Kari; Berg, Åse; Michelsen, Annika; Patel, Sam; Gregersen, Ida; Sagen, Ellen Lund; Halvorsen, Bente; Yndestad, Arne; Ueland, Thor; Langeland, Nina; Aukrust, Pål (Journal article; Peer reviewed, 2020)Background The immune response during falciparum malaria mediates both harmful and protective effects on the host; however the participating molecules have not been fully defined. Interleukin (IL)-27 is a pleiotropic ... -
Plasma parasitemia as assessed by quantitative PCR in relation to clinical disease severity in African adults with falciparum malaria with and without HIV co-infection
Berg, Åse; Patel, Sam; Tellevik, Marit Gjerde; Haanshuus, Christel Gill; Dalen, Ingvild; Otterdal, Kari; Ueland, Thor; Moyo, Sabrina John; Aukrust, Pål; Langeland, Nina (Journal article; Peer reviewed, 2020)Purpose When considering malaria disease severity, estimation of parasitemia in erythrocytes is important, but sometimes misleading, since the infected erythrocytes may be sequestered in peripheral capillaries. In African ... -
PNPLA 3 I148M genetic variant associates with insulin resistance and baseline viral load in HCV genotype 2 but not in genotype 3 infection
Rembeck, Karolina; Maglio, Cristina; Lagging, Martin; Christensen, Peer Brehm; Färkkilä, Martti; Langeland, Nina; Mørch, Kristine; Buhl, Mads R.; Pedersen, Court; Norkrans, Gunnar; Hellstrand, Kristoffer; Lindh, Magnus; Pirazzi, Carlo; Burza, Maria A.; Romeo, Stefano; Westin, Johan; for the NORDynamIC group (Peer reviewed; Journal article, 2012-09-14)Background: Hepatic steatosis in HCV patients has been postulated as a risk factor associated with a higher frequency of fibrosis and cirrhosis. A single genetic variant, PNPLA3 I148M, has been widely associated with ... -
Point-of-care influenza testing impacts clinical decision, patient flow and length of stay in hospitalized adults
Fjelltveit, Elisabeth Berg; Brokstad, Rebecca Jane Cox; Østensjø, Jørgen; Blomberg, Bjørn; Ebbesen, Marit Helen; Langeland, Nina; Mohn, Kristin Greve Isdahl (Journal article; Peer reviewed, 2022)Background Influenza is difficult to distinguish clinically from other acute respiratory infections. Rapid laboratory diagnosis can help initiate early effective antiviral treatment and isolation. Implementing a novel ... -
Post COVID-19 condition after delta infection and omicron reinfection in children and adolescents
Ertesvåg, Nina Urke; Iversen, Arild; Blomberg, Bjørn; Özgümüs, Türküler; Rijal, Pramila; Fjelltveit, Elisabeth Berg; Cox, Rebecca Jane; Langeland, Nina; Haug, Kjell; Sandnes, Helene Heitmann; Mohn, Kristin Greve-Isdahl; Olofsson, Jan Stefan; Sævik, Marianne; Brokstad, Christopher James; Kuwelker, Kanika; Heienberg, Kristin (Journal article; Peer reviewed, 2023)Background: The burden of COVID-19 in children and adolescents has increased during the delta and omicron waves, necessitating studies of long-term symptoms such as fatigue, dyspnoea and cognitive problems. Furthermore, ... -
Post epidemic giardiasis and gastrointestinal symptoms among preschool children in Bergen, Norway. A cross-sectional study
Mellingen, Kristin M.; Midtun, Anita; Hanevik, Kurt; Eide, Geir Egil; Søbstad, Øystein; Langeland, Nina (Peer reviewed; Journal article, 2010-03-26)Background A surprisingly low number of children became ill with giardiasis during the large waterborne outbreak of Giardia lamblia in Bergen, Norway during autumn 2004. The aim of the present study was to evaluate the ... -
Postinfectious and sporadic functional gastrointestinal disorders have different prevalences and rates of overlap: results from a controlled cohort study 3 years after acute giardiasis
Wensaas, Knut-Arne; Hanevik, Kurt; Hausken, Trygve; Eide, Geir Egil; Langeland, Nina; Mørch, Kristine; Rørtveit, Guri (Peer reviewed; Journal article, 2016)Background: Irritable bowel syndrome (IBS) is a common complication following gastroenteritis, and a high prevalence of postgiardiasis IBS has previously been reported. This study aims to investigate the prevalence, adjusted ... -
Predominance of PVL-negative community-associated methicillin-resistant Staphylococcus aureus sequence type 8 in newly diagnosed HIV-infected adults, Tanzania
Manyahi, Joel; Moyo, Sabrina John; Aboud, Said; Langeland, Nina; Blomberg, Bjørn (Journal article; Peer reviewed, 2021)Difficult-to-treat infections caused by methicillin-resistant Staphylococcus aureus (MRSA) are of concern in people living with HIV infection as they are more vulnerable to infection. We aimed to identify molecular ... -
Presence of interferon-λ 4, male gender, absent/mild steatosis and low viral load augment antibody levels to hepatitis C virus
Waldenström, Jesper; Hellstrand, Kristoffer; Westin, Johan; Nilsson, Staffan; Christensen, Peer; Färkkilä, Martti; Mørch, Kristine; Langeland, Nina; Norkrans, Gunnar; Lagging, Martin (Journal article; Peer reviewed, 2021)Objectives Despite recombinant interferon-λ 4 (IFN-λ4) demonstrating anti-viral activity in vitro and the ancestral functional gene (IFNL4) being conserved in all other primates, there has been speculation that IFN-λ4 may ... -
Prevalence and molecular characterisation of human adenovirus in diarrhoeic children in Tanzania; a case control study
Moyo, Sabrina John; Hanevik, Kurt; Blomberg, Bjørn; Kommedal, Øyvind; Nordbø, Svein Arne; Maselle, Samuel Y; Langeland, Nina (Peer reviewed; Journal article, 2014-12-12)Background: Human adenovirus (HAdV) causes acute diarrhoea sporadically, as well as in outbreaks. Understanding the prevalence and types of HAdV in diarrhoea is important for control and preventive measures, especially in ... -
Prevalence of Cryptosporidium parvum/hominis, Entamoeba histolytica and Giardia lamblia among Young Children with and without Diarrhea in Dar es Salaam, Tanzania
Tellevik, Marit Gjerde; Moyo, Sabrina John; Blomberg, Bjørn; Hjøllo, Torunn; Maselle, Samuel Y; Langeland, Nina; Hanevik, Kurt (Peer reviewed; Journal article, 2015-10-09)Background: Although enteroparasites are common causes of diarrheal illness, few studies have been performed among children in Tanzania. This study aimed to investigate the prevalence of Cryptosporidium parvum/hominis, ...