• Abuse and revictimization in adulthood in multiple sclerosis: a cross-sectional study during pregnancy 

      Eid, Karine; Torkildsen, Øivind; Aarseth, Jan Harald; Celius, Elisabeth Gulowsen; Cortese, Marianna; Holmøy, Trygve; Kapali, Akash; Myhr, Kjell-Morten; Torkildsen, Cecilie Fredvik; Wergeland, Stig; Gilhus, Nils Erik; Bjørk, Marte-Helene (Journal article; Peer reviewed, 2022)
      Background: Knowledge concerning exposure to abuse in adulthood and in pregnancy in people with multiple sclerosis (MS) is sparse. Objective: To determine the occurrence of adult abuse and abuse in relation to pregnancy ...
    • Antipsychotic use during pregnancy and risk of specific neurodevelopmental disorders and learning difficulties in children: a multinational cohort study 

      Bruno, Claudia; Cesta, Carolyn E.; Hjellvik, Vidar; Ulrichsen, Sinna Pilgaard; Bjørk, Marte-Helene; Esen, Buket Öztürk; Gillies, Malcolm B.; Gissler, Mika; Havard, Alys; Karlstad, Øystein; Leinonen, Maarit; Nørgaard, Mette; Pearson, Sallie-Anne; Reutfors, Johan; Furu, Kari; Cohen, Jacqueline Mallory; Zoega, Helga (Journal article; Peer reviewed, 2024)
      Background Antipsychotics are commonly prescribed to treat a range of psychiatric conditions in women of reproductive age and during pregnancy, including schizophrenia, bipolar disorder, anxiety, depression, autism ...
    • Antipsychotic use in pregnancy and risk of attention/ deficit-hyperactivity disorder and autism spectrum disorder: a Nordic cohort study 

      Halfdanarson, Oskar; Cohen, Jacqueline Mallory; Karlstad, Øystein; Cesta, Carolyn E.; Bjørk, Marte-Helene; Håberg, Siri Eldevik; Einarsdottir, Kristjana; Furu, Kari; Gissler, Mika; Hjellvik, Vidar; Kieler, Helle; Leinonen, Maarit; Nørgaard, Mette; Essen, Buket Öztürk; Ulrichsen, Sinna Pilgaard; Reutfors, Johan; Zoega, Helga (Journal article; Peer reviewed, 2021)
      Background Antipsychotics are increasingly used among women of childbearing age and during pregnancy. Objective To determine whether children exposed to antipsychotics in utero are at increased risk of attention-d ...
    • Association of adverse childhood experiences with the development of multiple sclerosis 

      Eid, Karine; Torkildsen, Øivind; Aarseth, Jan Harald; Aalstad, Mari; Bhan, Alok; Celius, Elisabeth Gulowsen; Cortese, Marianna; Daltveit, Anne Kjersti Nesje; Holmøy, Trygve; Myhr, Kjell-Morten; Riise, Trond; Schuler, Stephan; Torkildsen, Cecilie Fredvik; Wergeland, Stig; Gilhus, Nils Erik; Bjørk, Marte-Helene (Journal article; Peer reviewed, 2022)
      Objective To study whether exposure to childhood emotional, sexual or physical abuse is associated with subsequent multiple sclerosis (MS) development. Methods A nationwide, prospective cohort study based on participants ...
    • Association of Prenatal Exposure to Antiseizure Medication With Risk of Autism and Intellectual Disability 

      Bjørk, Marte-Helene; Zoega, Helga; Leinonen, Maarit K.; Cohen, Jacqueline Mallory; Dreier, Julie Werenberg; Furu, Kari; Gilhus, Nils Erik; Gissler, Mika; Halfdanarson, Oskar; Igland, Jannicke; Sun, Yuelian; Tomson, Torbjörn; Alvestad, Silje; Christensen, Jakob (Journal article; Peer reviewed, 2022)
      Importance: Women with epilepsy frequently need antiseizure medication (ASM) to prevent seizures in pregnancy. Risk of neurodevelopmental disorders after prenatal exposure to AMSs is uncertain. Objective: To determine ...
    • Cancer risk in children of mothers with epilepsy and high-dose folic acid use during pregnancy 

      Vegrim, Håkon Magne; Dreier, Julie Werenberg; Alvestad, Silje; Gilhus, Nils Erik; Gissler, Mika; Igland, Jannicke; Leinonen, Maarit; Tomson, Torbjörn; Sun, Yuelian; Zoega, Helga; Christensen, Jakob; Bjørk, Marte-Helene (Journal article; Peer reviewed, 2022)
      Importance: Women with epilepsy are recommended high doses of folic acid before and during pregnancy owing to risk of congenital anomalies associated with antiseizure medications. Whether prenatal exposure to high-dose ...
    • Comparative retention and effectiveness of migraine preventive treatments: A nationwide registry-based cohort study 

      Bjørk, Marte-Helene; Borkenhagen, Solveig; Oteiza, Francisco; Dueland, Aud N.; Sørgaard, Frank E.; Sæther, Erik Magnus; Bugge, Christoffer (Journal article; Peer reviewed, 2023)
      Background and purpose Little is known about the comparative effects of migraine preventive drugs. We aimed to estimate treatment retention and effectiveness of migraine preventive drugs in a nationwide registry-based ...
    • Comparative Risk of Major Congenital Malformations With Antiseizure Medication Combinations vs Valproate Monotherapy in Pregnancy 

      Cohen, Jacqueline Mallory; Alvestad, Silje; Suarez, Elizabeth A.; Schaffer, Andrea; Selmer, Randi M.; Havard, Alys; Bateman, Brian T.; Cesta, Carolyn E.; Zoega, Helga; Odsbu, Ingvild; Huybrechts, Krista F.; Kjerpeseth, Lars J.; Straub, Loreen; Leinonen, Maarit K.; Bjørk, Marte-Helene; Nørgaard, Mette; Gissler, Mika; Ulrichsen, Sinna P.; Hernandez-Diaz, Sonia; Tomson, Torbjörn; Furu, Kari (Journal article; Peer reviewed, 2023)
      Background and Objectives Valproate should be avoided in pregnancy, but it is the most effective drug for generalized epilepsies. Alternative treatment may require combinations of other drugs. Our objectives were to ...
    • Comparative Safety of Antiseizure Medication Monotherapy for Major Malformations 

      Cohen, Jacqueline Mallory; Alvestad, Silje; Cesta, Carolyn E.; Bjørk, Marte-Helene; Leinonen, Maarit; Nørgaard, Mette; Einarsdóttir, Kristjana; Engeland, Anders; Gissler, Mika; Karlstad, Øystein; Klungsøyr, Kari; Odsbu, Ingvild; Reutfors, Johan; Selmer, Randi Marie; Tomson, Torbjörn; Ulrichsen, Sinna Pilgaard; Zoega, Helga; Furu, Kari (Journal article; Peer reviewed, 2022)
      Objective: This study was undertaken to examine the comparative safety of antiseizure medication (ASM) monotherapy in pregnancy with respect to risk of major congenital malformations (MCMs), overall and by MCM subtype. ...
    • Continuous positive airway pressure in cluster headache: A randomized, placebo-controlled, triple-blind, crossover study 

      Gravdahl, Gøril Bruvik; Aakerøy, Lars; Stovner, Lars Jacob; Engstrøm, Morten; Müller, Kai Ivar; Bjørk, Marte-Helene; Tronvik, Erling Andreas (Journal article; Peer reviewed, 2023)
      Background Oxygen inhalation aborts cluster headache attacks, and case reports show the effect of continuous positive airway pressure. The aim of this study was to investigate the prophylactic effect of continuous positive ...
    • Does maternal genetic liability to folate deficiency influence the risk of antiseizure medication-associated language impairment and autistic traits in children of women with epilepsy? 

      Husebye, Elisabeth Synnøve Nilsen; Romanowska, Julia; Monsen, Anne-Lise Bjørke; Gilhus, Nils Erik; Selmer, Kaja Kristine; Gervin, Kristina; Riedel, Bettina Maria Ingeborg; Bjørk, Marte-Helene (Journal article; Peer reviewed, 2023)
      Background: Prenatal exposure to antiseizure medication (ASM) may lead to low plasma folate concentrations and is associated with impaired neurodevelopment. Objectives: To examine whether maternal genetic liability to ...
    • Effects of insufficient sleep on sensorimotor processing in migraine. A randomised, blinded crossover study of event related beta oscillations 

      Mykland, Martin Syvertsen; Uglem, Martin; Bjørk, Marte-Helene; Matre, Dagfinn; Sand, Trond Halfdan; Omland, Petter Moe (Journal article; Peer reviewed, 2023)
      Background Migraine has a largely unexplained connection with sleep and is possibly related to a dysfunction of thalamocortical systems and cortical inhibition. In this study we investigate the effect of insufficient sleep ...
    • Fluctuations of sensorimotor processing in migraine: A controlled longitudinal study of beta event related desynchronization 

      Mykland, Martin Syvertsen; Bjørk, Marte-Helene; Stjern, Marit; Omland, Petter Moe; Uglem, Martin; Sand, Trond (Peer reviewed; Journal article, 2019-07-09)
      Background: The migraine brain seems to undergo cyclic fluctuations of sensory processing. For instance, during the preictal phase, migraineurs experience symptoms and signs of altered pain perception as well as other ...
    • Folic Acid and Risk of Preterm Birth, Preeclampsia, and Fetal Growth Restriction Among Women With Epilepsy A Prospective Cohort Study 

      Alvestad, Silje; Husebye, Elisabeth Synnøve Nilsen; Christensen, Jakob; Dreier, Julie Werenberg; Sun, Yuelian; Igland, Jannicke; Leinonen, Maarit; Gissler, Mika; Gilhus, Nils Erik; Tomson, Torbjörn; Bjørk, Marte-Helene (Journal article; Peer reviewed, 2022)
      Background and Objectives Women with epilepsy treated with antiseizure medication (ASM) have increased risk of pregnancy complications including preterm birth, fetal growth restriction, and preeclampsia. We aimed to ...
    • Language impairment in children aged 5 and 8 years after antiepileptic drug exposure in utero – the Norwegian Mother and Child Cohort Study 

      Husebye, Elisabeth Synnøve Nilsen; Gilhus, Nils Erik; Spigset, Olav; Daltveit, Anne Kjersti; Bjørk, Marte-Helene (Peer reviewed; Journal article, 2020)
      Background and purpose: The purpose was to examine the consequences of antiepileptic drug (AED) exposure during pregnancy on language abilities in children aged 5 and 8 years of mothers with epilepsy. Methods: The study ...
    • Management of cluster headache and other trigeminal autonomic cephalalgias in pregnancy and breastfeeding 

      Bjørk, Marte-Helene; Kristoffersen, Espen Saxhaug; Tronvik, Erling Andreas; Nordeng, Hedvig Marie Egeland (Journal article; Peer reviewed, 2021)
      Many clinicians lack experience in managing trigeminal autonomic cephalalgias (TACs) in pregnancy and lactation. In addition to cluster headache, TACs include hemicrania continua, paroxysmal hemicrania, and short-lasting ...
    • Perinatal Depression and Anxiety in Women with Multiple Sclerosis: A Population-Based Cohort Study 

      Eid, Karine; Torkildsen, Øivind Fredvik Grytten; Aarseth, Jan Harald; Flemmen, Heidi Øyen; Holmøy, Trygve; Lorentzen, Åslaug Rudjord; Myhr, Kjell-Morten; Riise, Trond; Simonsen, Cecilia Smith; Torkildsen, Cecilie Fredvik; Wergeland, Stig; Willumsen, Johannes Sverre; Øksendal, Nina; Gilhus, Nils Erik; Bjørk, Marte-Helene (Journal article; Peer reviewed, 2021)
      Objective: To assess the occurrence of perinatal depression and anxiety in women before and after diagnosis of multiple sclerosis (MS). Methods: 114,629 pregnant women were included in the Norwegian Mother, Father and Child ...
    • Plasma unmetabolized folic acid in pregnancy and risk of autistic traits and language impairment in antiseizure medication-exposed children of women with epilepsy 

      Husebye, Elisabeth Synnøve Nilsen; Wendel, Annabel Willemijn Karine; Gilhus, Nils Erik; Riedel, Bettina Maria Ingeborg; Bjørk, Marte-Helene (Journal article; Peer reviewed, 2022)
      Background: Fetal exposure to unmetabolized folic acid (UMFA) during pregnancy may be associated with adverse neurodevelopment. Antiseizure medication (ASM) may interact with folate metabolism. Women with epilepsy using ...
    • Pregnancy, folic acid, and antiseizure medication 

      Bjørk, Marte-Helene; Vegrim, Håkon Magne; Alvestad, Silje; Monsen, Anne-Lise Bjørke; Riedel, Bettina Maria Ingeborg; Gilhus, Nils Erik; Husebye, Elisabeth Synnøve Nilsen (Journal article; Peer reviewed, 2023)
      Background Although some antiseizure medications (ASMs) are teratogenic, most people with epilepsy need treatment in pregnancy. The risk of ASM fetotoxicity may be mitigated with folic acid. High-dose folic acid ...
    • Prescribing patterns for higher dose folic acid in pregnant women with epilepsy treated with antiseizure medication 

      Vegrim, Håkon Magne; Dreier, Julie Werenberg; Igland, Jannicke; Gilhus, Nils Erik; Alvestad, Silje; Gissler, Mika; Leinonen, Maarit; Sun, Yuelian; Zoega, Helga; Christensen, Jakob; Bjørk, Marte-Helene; Tomson, Torbjörn (Journal article; Peer reviewed, 2024)
      Objective: This study was undertaken to characterize the use of higher doses of folic acid (≥1 mg daily) in relation to pregnancy in Denmark, Norway, and Sweden in women with epilepsy treated with antiseizure medication ...