Browsing Bergen Open Research Archive by Author "Oksenych, Valentyn"
Now showing items 1-7 of 7
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Altered Blood Molecular Markers of Cardiovascular Function in Rats after Intrauterine Hypoxia and Drug Therapy
Popazova, Olena; Belenichev, Igor; Yadlovskyi, Oleh; Oksenych, Valentyn; Kamyshnyi, Aleksandr (Journal article; Peer reviewed, 2023)Many children and adults who have suffered prenatal hypoxia at an early age develop many serious diseases. This disease is an actual problem of pediatric cardiology and little studied. The aim was to analyze the cardioprotective ... -
Association of Myocardial Changes and Gene Expression of the NFATC1 and NFATC4—Calcineurin Signaling Pathway in Children with Bicuspid Aortic Valve
Kamenshchyk, Andrii; Gonchar, Margaryta; Oksenych, Valentyn; Kamyshnyi, Aleksandr (Journal article; Peer reviewed, 2023)Background: The role of NFATC gene expression in bicuspid aortic valve (BAV) progression is not fully understood. The aim of this study is to determine the significance of NFATC1 and NFATC4 gene expression for myocardial ... -
Cardioprotective Activity of Pharmacological Agents Affecting NO Production and Bioavailability in the Early Postnatal Period after Intrauterine Hypoxia in Rats
Popazova, Olena; Belenichev, Igor; Bukhtiyarova, Nina; Ryzhenko, Victor; Oksenych, Valentyn; Kamyshnyi, Aleksandr (Journal article; Peer reviewed, 2023)Intrauterine hypoxia in newborns leads to a multifaceted array of alterations that exert a detrimental impact on the cardiovascular system. The aim of this research was to assess the cardioprotective effects of modulators ... -
Common nodes of virus-host interaction revealed through an integrated network analysis
Bösl, Korbinian; Ianevski, Aleksandr; Than, Thoa T.; Andersen, Petter I.; Kuivanen, Suvi; Teppor, Mona; Zusinaite, Eva; Dumpis, Uga; Vitkauskiene, Astra; Cox, Rebecca Jane; Kallio-Kokko, Hannimari; Bergqvist, Anders; Tenson, Tanel; Merits, Andres; Oksenych, Valentyn; Bjørås, Magnar; Anthonsen, Marit Walbye; Shum, David H.K.; Kaarbø, Mari; Vapalahti, Olli; Windisch, Marc P.; Superti-Furga, Giulio; Snijder, Berend; Kainov, Denis; Kandasamy, Richard Kumaran (Peer reviewed; Journal article, 2019-10-04)Viruses are one of the major causes of acute and chronic infectious diseases and thus a major contributor to the global burden of disease. Several studies have shown how viruses have evolved to hijack basic cellular pathways ... -
Genetic Predictors of Comorbid Course of COVID-19 and MAFLD: A Comprehensive Analysis
Buchynskyi, Mykhailo; Oksenych, Valentyn; Kamyshna, Iryna; Vari, Sandor G.; Kamyshnyi, Aleksandr (Journal article; Peer reviewed, 2023)Metabolic-associated fatty liver disease (MAFLD) and its potential impact on the severity of COVID-19 have gained significant attention during the pandemic. This review aimed to explore the genetic determinants associated ... -
Low temperature and low UV indexes correlated with peaks of influenza virus activity in Northern Europe during 2010-2018
Ianevski, Aleksandr; Zusinaite, Eva; Shtaida, Nastassia; Kallio-Kokko, Hannimari; Valkonen, Mia; Kantele, Anu; Telling, Kaidi; Lutsar, Irja; Letjuka, Pille; Metelitsa, Natalja; Oksenych, Valentyn; Dumpis, Uga; Vitkauskiene, Astra; Stašaitis, Kestutis; Öhrmalm, Christina; Bondeson, Kåre; Bergqvist, Anders; Cox, Rebecca Jane; Tenson, Tanel; Merits, Andres; Kainov, Denis (Peer reviewed; Journal article, 2019-03-01)With the increasing pace of global warming, it is important to understand the role of meteorological factors in influenza virus (IV) epidemics. In this study, we investigated the impact of temperature, UV index, humidity, ... -
Metformin Therapy Changes Gut Microbiota Alpha-Diversity in COVID-19 Patients with Type 2 Diabetes: The Role of SARS-CoV-2 Variants and Antibiotic Treatment
Petakh, Pavlo; Kamyshna, Iryna; Oksenych, Valentyn; Kainov, Denis; Kamyshnyi, Aleksandr (Journal article; Peer reviewed, 2023)The gut microbiota play a crucial role in maintaining host health and have a significant impact on human health and disease. In this study, we investigated the alpha diversity of gut microbiota in COVID-19 patients and ...