Browsing Bergen Open Research Archive by Author "Zhu, Huaiyang"
Now showing items 1-3 of 3
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A co-culture model with brain tumor-specific bioluminescence demonstrates astrocyte-induced drug resistance in glioblastoma
Yang, Ning; Yan, Tao; Zhu, Huaiyang; Liang, Xiao; Leiss, Lina; Sakariassen, Per Øystein; Skaftnesmo, Kai Ove; Huang, Bin; Costea, Daniela Elena; Enger, Per Øyvind; Li, Xingang; Wang, Jian (Peer reviewed; Journal article, 2014-10-04)Background: Although several studies suggest that stromal fibroblasts mediate treatment resistance in several cancer types, little is known about how tumor-associated astrocytes modulate the treatment response in brain ... -
A novel GFP nude rat model to investigate tumor-stroma interactions
Yang, Ning; Huang, Bin; Tsinkalovsky, Oleg; Brekkå, Narve; Zhu, Huaiyang; Leiss, Lina; Enger, Per Øyvind; Li, Xingang; Wang, Jian (Peer reviewed; Journal article, 2014-12-21)Backgroud: A key strategy for the study of the tumor microenvironment is to implant human tumor cells in an immunodeficient rodent strain ubiquitously expressing a fluorescent marker. Here, a novel nude rat expressing a ... -
Surgical debulking promotes recruitment of macrophages and triggers glioblastoma phagocytosis in combination with CD47 blocking immunotherapy
Zhu, Huaiyang; Leiss, Lina Wik; Yang, Ning; Rygh, Cecilie Brekke; Mitra, Siddharta S.; Cheshier, Samuel H.; Weissman, Irving L.; Huang, Bin; Miletic, Hrvoje; Bjerkvig, Rolf; Enger, Per Øyvind; Li, Xingang; Wang, Jian (Peer reviewed; Journal article, 2017)Surgical resection is a standard component of treatment in the clinical management of patients with glioblastoma multiforme (GBM). However, experimental therapies are rarely investigated in the context of tumor debulking ...