Blar i Bergen Open Research Archive på forfatter "Angelsen, Jon-Helge"
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Aspirin as secondary prevention in colorectal cancer liver metastasis (ASAC trial): study protocol for a multicentre randomized placebo-controlled trial
Yaqub, Sheraz; Bjørnbeth, Bjørn Atle; Angelsen, Jon-Helge; Fristrup, Claus W.; Grønbech, Jon Erik; Hemmingsson, Oskar; Isaksson, Bengt; Juel, Ingebjørg Soterud; Larsen, Peter Nørgaard; Lindell, Gert; Mortensen, Frank V.; Mortensen, Kim Erlend; Rizell, Magnus; Sandström, Per; Sandvik, Oddvar Mathias; Sparrelid, Ernesto; Taflin, Helena; Taskén, Kjetil; Brudvik, Kristoffer Watten; Fretland, Åsmund Avdem; Horn, Arild; Kleive, Dyre; Labori, Knut Jørgen; Lassen, Kristoffer; Røsok, Bård Ingvald; Søreide, Jon Arne; Tholfsen, Tore; Villanger, Olaug; Waage, Anne (Journal article; Peer reviewed, 2021)Background Colorectal cancer is one the most common cancers in the western world with increasing incidence. Approximately 50% of the patients develop liver metastases. Resection of liver metastases is the treatment of ... -
Impact of KRAS, BRAF, PIK3CA, TP53 status and intraindividual mutation heterogeneity on outcome after liver resection for colorectal cancer metastases
Løes, Inger Marie; Immervoll, Heike; Sorbye, Halfdan; Angelsen, Jon-Helge; Horn, Arild; Knappskog, Stian; Lønning, Per Eystein (Peer reviewed; Journal article, 2016-04)We determined prognostic impact of KRAS, BRAF, PIK3CA and TP53 mutation status and mutation heterogeneity among 164 colorectal cancer (CRC) patients undergoing liver resections for metastatic disease. Mutation status was ... -
Percutaneous cholecystostomy in acutecholecystitis; a retrospective analysis of a largeseries of 104 patients
Viste, Asgaut; Jensen, Dag Kjartan; Angelsen, Jon-Helge; Hoem, Dag (Peer reviewed; Journal article, 2015-03-08)Background: The purpose of this study was to evaluate the clinical course and possible benefit of a percutaneous cholecystostomy in patients with acute cholecystitis. Methods: Retrospective study of 104 patients with severe ... -
Performance comparison of three BRAF V600E detection methods in malignant melanoma and colorectal cancer specimen
Løes, Inger Marie; Immervoll, Heike; Angelsen, Jon-Helge; Horn, Arild; Geisler, Jürgen; Busch, Christian; Lønning, Per Eystein; Knappskog, Stian (Peer reviewed; Journal article, 2015-02)Personalized cancer care requires reliable biomarkers. While the BRAF V600E mutation is implemented in the clinic, no method for its detection has so far been established as reference. We aimed to perform a comprehensive ... -
Practice patterns in diagnostics, staging, and management strategies of gallbladder cancer among Nordic tertiary centers
Takala, Sini; Lassen, Kristoffer; Søreide, Kjetil; Sparrelid, Ernesto; Angelsen, Jon-Helge; Bringeland, Erling Audun; Eilard, Malin S.; Hemmingsson, Oskar; Isaksson, Bengt; Karjula, Heikki; Lammi, Jukka-Pekka; Larsen, Peter N.; Lavonius, Maija; Lindell, Gert; Mortensen, Frank V.; Mortensen, Kim Erlend; Nordin, Arno; Pless, Torsten; Sandström, Per; Sandvik, Oddvar Mathias; Vaalavuo, Yrjö; Villard, Christina; Sallinen, Ville (Journal article; Peer reviewed, 2023)Background and objective: Gallbladder cancer (GBC) is a rare malignancy in the Nordic countries and no common Nordic treatment guidelines exist. This study aimed to characterize the current diagnostic and treatment ... -
Predictive factors for time to recurrence, treatment and post-recurrence survival in patients with initially resected colorectal liver metastases
Angelsen, Jon-Helge; Viste, Asgaut; Løes, Inger Marie; Eide, Geir Egil; Hoem, Dag; Sorbye, Halfdan; Horn, Arild (Peer reviewed; Journal article, 2015-12-03)Background: Despite progress in resection for colorectal liver metastases (CLM), the majority of patients experience recurrence. We aimed to evaluate factors influencing time to recurrence (TTR), treatment and post-recurrence ... -
Resection rates and predictors of survival after surgery for colorectal liver metastases
Angelsen, Jon-Helge (Doctoral thesis, 2017-10-20)Introduction: Occurrence of liver metastases is common following colorectal cancer (CRC), and resection is the only option with a potential for cure offered to a minor part of these patients. During the last decades there ... -
Simultaneous Resection of Primary Colorectal Cancer and Synchronous Liver Metastases: Contemporary Practice, Evidence and Knowledge Gaps
Kleive, Dyre; Aas, Eline; Angelsen, Jon-Helge; Bringeland, Erling Audun; Nesbakken, Arild; Nymo, Linn Såve; Schultz, Johannes Kurt; Søreide, Kjetil; Yaqub, Sheraz (Journal article; Peer reviewed, 2021)The timing of surgical resection of synchronous liver metastases from colorectal cancer has been debated for decades. Several strategies have been proposed, but high-level evidence remains scarce. Simultaneous resection ... -
Surgery for colorectal liver metastases: the impact of resection margins on recurrence and overall survival
Angelsen, Jon-Helge; Horn, Arild; Eide, Geir Egil; Viste, Asgaut (Peer reviewed; Journal article, 2014-04-27)Background: Several reports have presented conflicting results regarding the association between resection margins (RMs) and outcome after surgery for colorectal liver metastases (CLM), especially in the era of modern ...