Blar i Bergen Open Research Archive på forfatter "Dahl, Olav"
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Activity monitoring and patient-reported outcome measures in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome patients
Rekeland, Ingrid Gurvin; Sørland, Kari; Bruland, Ove; Risa, Kristin; Alme, Kine; Dahl, Olav; Tronstad, Karl Johan; Mella, Olav; Fluge, Øystein (Journal article; Peer reviewed, 2022-09-19)Introduction: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a disease with no validated specific and sensitive biomarker, and no standard approved treatment. In this observational study with no intervention, ... -
Benefit from B-Lymphocyte Depletion Using the Anti- CD20 Antibody Rituximab in Chronic Fatigue Syndrome. A Double-Blind and Placebo-Controlled Study
Fluge, Øystein; Bruland, Ove; Risa, Kristin; Storstein, Anette; Kristoffersen, Einar K.; Sapkota, Dipak; Næss, Halvor; Dahl, Olav; Nyland, Harald; Mella, Olav (Peer reviewed; Journal article, 2011-10-19)Background: Chronic fatigue syndrome (CFS) is a disease of unknown aetiology. Major CFS symptom relief during cancer chemotherapy in a patient with synchronous CFS and lymphoma spurred a pilot study of B-lymphocyte depletion ... -
Brainstem NTCP and dose constraints for carbon ion RT—Application and translation from Japanese to European RBE-weighted dose
Dale, Jon Espen; Molinelli, Silvia; Vischioni, Barbara; Vitolo, Viviana; Bonora, Maria; Magro, Giuseppe; Mairani, Andrea; Hasegawa, Azusa; Ohno, Tatsuya; Dahl, Olav; Valvo, Francesca; Fossati, Piero (Journal article; Peer reviewed, 2020)Background and Purpose: The Italian National Center of Oncological Hadrontherapy (CNAO) has applied dose constraints for carbon ion RT (CIRT) as defined by Japan’s National Institute of Radiological Sciences (NIRS). However, ... -
Intravenous Cyclophosphamide in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. An Open-Label Phase II Study
Rekeland, Ingrid Gurvin; Fosså, Alexander; Lande, Asgeir; Ktoridou-Valen, Irini; Sørland, Kari; Holsen, Mari; Tronstad, Karl Johan; Risa, Kristin; Alme, Kine; Viken, Marte Katrine; Lie, Benedicte Alexandra; Dahl, Olav; Mella, Olav; Fluge, Øystein (Journal article; Peer reviewed, 2020)Introduction: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a disease with high symptom burden, of unknown etiology, with no established treatment. We observed patients with long-standing ME/CFS who got ... -
Long-Term Outcome in a Phase II Study of Regional Hyperthermia Added to Preoperative Radiochemotherapy in Locally Advanced and Recurrent Rectal Adenocarcinomas
Schem, Baard-Christian; Pfeffer, Frank; Ott, Martin Anton; Wiig, Johan N.; Sletteskog, Nils; Frøystein, Torbjørn; Myklebust, Mette Pernille; Leh, Sabine; Dahl, Olav; Mella, Olav (Journal article; Peer reviewed, 2022-01-29)Hyperthermia was added to standard preoperative chemoradiation for rectal adenocarcinomas in a phase II study. Patients with T3-4 N0-2 M0 rectal cancer or local recurrences were included. Radiation dose was 54 Gy combined ... -
A map of metabolic phenotypes in patients with myalgic encephalomyelitis/chronic fatigue syndrome
Hoel, Fredrik; Hoel, August; Pettersen, Ina Katrine Nitschke; Rekeland, Ingrid Gurvin; Risa, Kristin; Alme, Kine; Sørland, Kari; Fosså, Alexander; Lien, Katarina; Herder, Ingrid; Thurmer, Hanne; Gotaas, Merethe Otelie Eide; Schäfer, Christoph; Berge, Rolf K.; Sommerfelt, Kristian; Marti, Hans Peter; Dahl, Olav; Mella, Olav; Fluge, Øystein; Tronstad, Karl Johan (Journal article; Peer reviewed, 2021)Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating disease usually presenting after infection. Emerging evidence supports that energy metabolism is affected in ME/CFS, but a unifying metabolic ... -
Mapping Proteome Changes in Microsatellite Stable, Recurrent Colon Cancer Reveals a Significant Immune System Signature
Berle, Magnus; Hestetun, Kjersti Elvestad; Vethe, Heidrun; Chera, Simona; Paulo, Joao A.; Dahl, Olav; Myklebust, Mette Pernille (Journal article; Peer reviewed, 2022)Background/Aim: Better stratification of the risk of relapse will help select the right patients for adjuvant treatment and improve targeted therapies for patients with colon cancer. Materials and Methods: To understand ... -
MicroRNAs in Differentiation of Embryoid Bodies and the Teratoma Subtype of Testicular Cancer
Myklebust, Mette Pernille; Søviknes, Anne Mette; Halvorsen, Ole Johan; Thor, Anna; Dahl, Olav; Ræder, Helge (Journal article; Peer reviewed, 2022)Background: Testicular germ cell tumours (TGCTs) are the most frequent tumour type among young, adult men. TGCTs can be efficiently treated, but metastases of the teratoma subtype, for which there are no circulating ... -
Optic nerve constraints for carbon ion RT at CNAO ? Reporting and relating outcome to European and Japanese RBE
Dale, Jon Espen; Molinelli, Silvia; Vitolo, Viviana; Vischioni, Barbara; Bonora, Maria; Magro, Giuseppe; Pettersen, Helge Egil Seime; Mairani, Andrea; Hasegawa, Azusa; Dahl, Olav; Valvo, Francesca; Fossati, Piero (Peer reviewed; Journal article, 2019)Background and purpose: Until now, carbon ion RT (CIRT) dose constraints for the optic nerve (ON) have only been validated and reported in the NIRS RBE-weighted dose (DNIRS). The aim of this work is to improve CNAO’s ... -
Prognostic significance of S100A4 expression in stage II and III colorectal cancer: results from a population-based series and a randomized phase III study on adjuvant chemotherapy
Pedersen, Kjetil Boye; Jacob, Havjin; Frikstad, Kari-Anne; Nesland, Jahn M; Mælandsmo, Gunhild; Dahl, Olav; Nesbakken, Arild; Flatmark, Kjersti (Peer reviewed; Journal article, 2016-08)Current clinical algorithms are unable to precisely predict which colorectal cancer patients would benefit from adjuvant chemotherapy, and there is a need for novel biomarkers to improve the selection of patients. The ... -
Quantitative PCR Measurement of miR-371a-3p and miR-372-p Is Influenced by Hemolysis
Myklebust, Mette Pernille; Rosenlund, Benedicte; Gjengstø, Peder; Bercea, Bogdan Stefan; Karlsdottir, Åsa; Brydøy, Marianne; Dahl, Olav (Peer reviewed; Journal article, 2019-05-22)Cell-free microRNAs have been reported as biomarkers for several diseases. For testicular germ cell tumors (GCT), circulating microRNAs 371a-3p and 372-3p in serum and plasma have been proposed as biomarkers for diagnostic ... -
Spatial Agreement of Brainstem Dose Distributions Depending on Biological Model in Proton Therapy for Pediatric Brain Tumors
Fjæra, Lars Fredrik; Indelicato, Daniel J.; Ytre-Hauge, Kristian; Muren, Ludvig Paul; Lassen-Ramshad, Yasmin; Toussaint, Laura; Dahl, Olav; Stokkevåg, Camilla Hanquist (Journal article; Peer reviewed, 2021)Purpose During radiation therapy for pediatric brain tumors, the brainstem is a critical organ at risk, possibly with different radio-sensitivity across its substructures. In proton therapy, treatment planning is currently ... -
Sperm counts and endocrinological markers of spermatogenesis in long-term survivors of testicular cancer
Brydøy, Marianne; Fosså, Sophie Dorothea; Klepp, Olbjørn; Bremnes, Roy M.; Wist, Erik; Bjøro, Trine; Wentzel-Larsen, Tore; Dahl, Olav (Journal article; Peer reviewed, 2012)Background: The objective of this study was to assess markers of spermatogenesis in long-term survivors of testicular cancer (TC) according to treatment, and to explore correlations between the markers and associations ... -
Stage-dependent prognostic shift in mismatch repair-deficient tumors: Assessing patient outcomes in stage II and III colon cancer
Hestetun, Kjersti Elvestad; Rosenlund, Nina Benedikte; Stanisavljevic, Luka; Dahl, Olav; Myklebust, Mette Pernille (Journal article; Peer reviewed, 2022)Introduction: Deficient mismatch repair (dMMR) or high microsatellite instability (MSI-H) is associated with an improved prognosis in colon cancer stage II but poor prognosis in stage IV colon cancer. The clinical significance ... -
Ten-Year Results From a Phase II Study on Image Guided, Intensity Modulated Radiation Therapy With Simultaneous Integrated Boost in High-Risk Prostate Cancer
Ekanger, Christian; Helle, Svein Inge; Heinrich, Daniel; Johannessen, Dag Clement; Karlsdottir, Åsa; Nygård, Yngve; Halvorsen, Ole Johan; Reisæter, Lars Anders Rokne; Kvåle, Rune; Hysing, Liv Bolstad; Dahl, Olav (Journal article; Peer reviewed, 2020)Purpose There is no consensus on how to treat high-risk prostate cancer, and long-term results from hypofractionated radiation therapy are lacking. We report 10-year results after image guided, intensity modulated radiation ...