Blar i Bergen Open Research Archive på forfatter "Edwin, Trine Holt"
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Higher concentrations of kynurenic acid in CSF are associated with the slower clinical progression of Alzheimer's disease
Knapskog, Anne Brita; Aksnes, Mari; Edwin, Trine Holt; Ueland, Per Magne; Ulvik, Arve; Fang, Fei; Eldholm, Rannveig Sakshaug; Halaas, Nathalie Bodd; Saltvedt, Ingvild Tina; Giil, Lasse Melvær; Watne, Leiv (Journal article; Peer reviewed, 2023)Introduction: The kynurenine pathway's (KP) malfunction is closely related to Alzheimer's disease (AD), for antagonistic kynurenic acid (KA) and agonistic quinolinic acid act on the N-methyl-D-aspartate receptor, a possible ... -
Trajectories of occupational physical activity and risk of later-life mild cognitive impairment and dementia: the HUNT4 70+ study
Zotcheva, Ekaterina; Bratsberg, Bernt Magne; Strand, Bjørn Heine; Jugessur, Astanand; Engdahl, Bo Lars; Bowen, Catherine; Selbæk, Geir; Kohler, Hans-Peter; Harris, Jennifer Ruth; Weiss, Jordan; Tom, Sarah E.; Krokstad, Steinar; Yitayew, Teferi Mekonnen; Edwin, Trine Holt; Stern, Yaakov; Håberg, Asta Kristine; Skirbekk, Vegard Fykse (Journal article; Peer reviewed, 2023)Background High levels of occupational physical activity (PA) have been linked to an increased risk of dementia. We assessed the association of trajectories of occupational PA at ages 33–65 with risk of dementia and ...