Blar i Bergen Open Research Archive på forfatter "Mella, Olav"
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Activity monitoring and patient-reported outcome measures in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome patients
Rekeland, Ingrid Gurvin; Sørland, Kari; Bruland, Ove; Risa, Kristin; Alme, Kine; Dahl, Olav; Tronstad, Karl Johan; Mella, Olav; Fluge, Øystein (Journal article; Peer reviewed, 2022-09-19)Introduction: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a disease with no validated specific and sensitive biomarker, and no standard approved treatment. In this observational study with no intervention, ... -
AIDS-related primary central nervous system lymphoma: a Norwegian national survey 1989–2003
Haldorsen, Ingfrid S.; Kråkenes, Jostein; Goplen, Anne Kristin; Dunlop, Oona; Mella, Olav; Espeland, Ansgar (Peer reviewed; Journal article, 2008-08-06)Background: Primary central nervous system lymphoma (PCNSL) is a frequent complication in acquired immunodeficiency syndrome (AIDS). The objective of this survey was to investigate incidence, clinical features, radiological ... -
Benefit from B-Lymphocyte Depletion Using the Anti- CD20 Antibody Rituximab in Chronic Fatigue Syndrome. A Double-Blind and Placebo-Controlled Study
Fluge, Øystein; Bruland, Ove; Risa, Kristin; Storstein, Anette; Kristoffersen, Einar K.; Sapkota, Dipak; Næss, Halvor; Dahl, Olav; Nyland, Harald; Mella, Olav (Peer reviewed; Journal article, 2011-10-19)Background: Chronic fatigue syndrome (CFS) is a disease of unknown aetiology. Major CFS symptom relief during cancer chemotherapy in a patient with synchronous CFS and lymphoma spurred a pilot study of B-lymphocyte depletion ... -
Early rehabilitation of cancer patients - a randomized controlled intervention study
Arving, Cecilia; Thormodsen, Inger; Brekke, Guri; Mella, Olav; Berntsen, Sveinung; Nordin, Karin (Peer reviewed; Journal article, 2013-01-07)Background: Faced with a life-threatening illness, such as cancer, many patients develop stress symptoms, i.e. avoidance behaviour, intrusive thoughts and worry. Stress management interventions have proven to be effective; ... -
Endothelial dysfunction in ME/CFS patients
Sandvik, Miriam Kristine; Sørland, Kari; Leirgul, Elisabeth; Rekeland, Ingrid Gurvin; Stavland, Christina Særsten; Mella, Olav; Fluge, Øystein (Journal article; Peer reviewed, 2023-02-02)Objective: A few earlier studies have found impaired endothelial function in patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). The present study investigated large-vessel and small-vessel endothelial ... -
Fine mapping of the major histocompatibility complex (MHC) in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) suggests involvement of both HLA class I and class II loci
Hajdarevic, Riad; Lande, Asgeir; Rekeland, Ingrid Gurvin; Rydland, Anne; Strand, Elin B.; Sosa, Daysi Duarte; Creary, Lisa E; Mella, Olav; Egeland, Torstein; Saugstad, Ola Didrik; Fluge, Øystein; Lie, Benedicte Alexandra; Viken, Marte Kathrine (Journal article; Peer reviewed, 2021)The etiology of myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is unknown, but involvement of the immune system is one of the proposed underlying mechanisms. Human leukocyte antigen (HLA) associations are ... -
Human Leukocyte Antigen alleles associated with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
Lande, Asgeir; Fluge, Øystein; Strand, Elin Bolle; Flåm, Siri Tennebø; Sosa, Daisy Duarte; Mella, Olav; Egeland, Torstein; Saugstad, Ola Didrik; Lie, Benedicte Alexandra; Viken, Marte K (Journal article; Peer reviewed, 2020)The etiology and pathogenesis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) are unknown, and autoimmunity is one of many proposed underlying mechanisms. Human Leukocyte Antigen (HLA) associations are ... -
Intravenous Cyclophosphamide in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. An Open-Label Phase II Study
Rekeland, Ingrid Gurvin; Fosså, Alexander; Lande, Asgeir; Ktoridou-Valen, Irini; Sørland, Kari; Holsen, Mari; Tronstad, Karl Johan; Risa, Kristin; Alme, Kine; Viken, Marte Katrine; Lie, Benedicte Alexandra; Dahl, Olav; Mella, Olav; Fluge, Øystein (Journal article; Peer reviewed, 2020)Introduction: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a disease with high symptom burden, of unknown etiology, with no established treatment. We observed patients with long-standing ME/CFS who got ... -
Long-Term Outcome in a Phase II Study of Regional Hyperthermia Added to Preoperative Radiochemotherapy in Locally Advanced and Recurrent Rectal Adenocarcinomas
Schem, Baard-Christian; Pfeffer, Frank; Ott, Martin Anton; Wiig, Johan N.; Sletteskog, Nils; Frøystein, Torbjørn; Myklebust, Mette Pernille; Leh, Sabine; Dahl, Olav; Mella, Olav (Journal article; Peer reviewed, 2022-01-29)Hyperthermia was added to standard preoperative chemoradiation for rectal adenocarcinomas in a phase II study. Patients with T3-4 N0-2 M0 rectal cancer or local recurrences were included. Radiation dose was 54 Gy combined ... -
A map of metabolic phenotypes in patients with myalgic encephalomyelitis/chronic fatigue syndrome
Hoel, Fredrik; Hoel, August; Pettersen, Ina Katrine Nitschke; Rekeland, Ingrid Gurvin; Risa, Kristin; Alme, Kine; Sørland, Kari; Fosså, Alexander; Lien, Katarina; Herder, Ingrid; Thurmer, Hanne; Gotaas, Merethe Otelie Eide; Schäfer, Christoph; Berge, Rolf K.; Sommerfelt, Kristian; Marti, Hans Peter; Dahl, Olav; Mella, Olav; Fluge, Øystein; Tronstad, Karl Johan (Journal article; Peer reviewed, 2021)Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating disease usually presenting after infection. Emerging evidence supports that energy metabolism is affected in ME/CFS, but a unifying metabolic ... -
No replication of previously reported association with genetic variants in the T cell receptor alpha (TRA) locus for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)
Ueland, Marthe; Hajdarevic, Riad; Mella, Olav; Strand, Elin Bolle; Daysi Duarte, Sosa; Saugstad, Ola Didrik; Fluge, Øystein; Lie, Benedicte Alexandra; Viken, Marte Kathrine (Journal article; Peer reviewed, 2022)Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disease with a variety of symptoms such as post-exertional malaise, fatigue, and pain, but where aetiology and pathogenesis are unknown. An increasing number ... -
Reduced Endothelial Function in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome–Results From Open-Label Cyclophosphamide Intervention Study
Sørland, Kari; Sandvik, Miriam Kristine; Rekeland, Ingrid Gurvin; Ribu, Lis; Småstuen, Milada Cvancarova; Mella, Olav; Fluge, Øystein (Journal article; Peer reviewed, 2021)Introduction: Patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) present with a range of symptoms including post-exertional malaise (PEM), orthostatic intolerance, and autonomic dysfunction. Dysfunction ... -
Understanding, diagnosing, and treating Myalgic encephalomyelitis/chronic fatigue syndrome – State of the art: Report of the 2nd international meeting at the Charité Fatigue Center
Steiner, Sophie; Fehrer, Annick; Hoheisel, Friederike; Schoening, Simon; Aschenbrenner, Anna; Babel, Nina; Bellmann-Strobl, Judith; Finke, Carsten; Fluge, Øystein; Froehlich, Laura; Goebel, Andreas; Grande, Bettina; Haas, Johannes-Peter; Hohberger, Bettina; Jason, Leonard A.; Komaroff, Anthony L.; Lacerda, Eliana; Liebl, Max; Maier, Andrea; Mella, Olav; Nacul, Luis; Paul, Friedemann; Prusty, Bhupesh K.; Puta, Christian; Riemekasten, Gabriela; Ries, Wolfgang; Rowe, Peter C.; Sawitzki, Birgit; Shoenfeld, Yehuda; Schultze, Joachim L.; Seifert, Martina; Sepúlveda, Nuno; Sotzny, Franziska; Stein, Elisa; Stingl, Michael; Ufer, Friederike; Veauthier, Christian; Westermeier, Francisco; Wirth, Klaus; Wolfarth, Bernd; Zalewski, Pawel; Behrends, Uta; Scheibenbogen, Carmen (Journal article; Peer reviewed, 2023)Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a devastating disease affecting millions of people worldwide. Due to the 2019 pandemic of coronavirus disease (COVID-19), we are facing a significant increase ...