Blar i Bergen Open Research Archive på forfatter "Singh, Dave"
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Assessing the Anti-Inflammatory Effects of an Orally Dosed Enzymatically Liberated Fish Oil in a House Dust Model of Allergic Asthma
Currie, Crawford; Framroze, Bomi; Singh, Dave; Lea, Simon; Bjerknes, Christian; Hermansen, Erland (Journal article; Peer reviewed, 2022-10-14)Eosinophils are a major driver of inflammation in a number of human diseases, including asthma. Biologic therapies targeting IL-5 have enabled better control of severe eosinophilic asthma, but no such advances have been ... -
Genetics of Sputum Gene Expression in Chronic Obstructive Pulmonary Disease
Qiu, Weiliang; Cho, Michael H.; Riley, John H.; Anderson, Wayne H.; Singh, Dave; Bakke, Per; Gulsvik, Amund; Litonjua, Augusto A.; Lomas, David A.; Crapo, James D.; Beaty, Terri H.; Celli, Bartolome R.; Rennard, Stephen I.; Tal-Singer, Ruth; Fox, Steven M.; Silverman, Edwin K.; Hersh, Craig P. (Peer reviewed; Journal article, 2011-09-16)Previous expression quantitative trait loci (eQTL) studies have performed genetic association studies for gene expression, but most of these studies examined lymphoblastoid cell lines from non-diseased individuals. We ... -
Pharmacological evaluation of the effects of enzymatically liberated fish oil on eosinophilic inflammation in animal models
Currie, Crawford; Framroze, Bomi; Singh, Dave; Sharma, Deepali; Bjerknes, Christian; Hermansen, Erland (Journal article; Peer reviewed, 2022)The inappropriate activation of eosinophils is a well-recognized driver of various human inflammatory diseases including asthma, chronic rhinitis, and various gastrointestinal diseases, including eosinophilic esophagitis. ...