• Life expectancy and disease burden in the Nordic countries: results from the Global Burden of Diseases, Injuries, and Risk Factors Study 2017 

      Kisa, Adnan; Knudsen, Ann Kristin; Allebeck, Peter; Tollånes, Mette Christophersen; Skogen, Jens Christoffer; Iburg, Kim Moesgaard; McGrath, John J; Juel, Knud; Agardh, Emilie Elisabet; Arnlöv, Johan; Bjørge, Tone; Carrero, Juan J.; Cederroth, Christopher R; Eggen, Anne Elise; El-Khatib, Ziad; Lycke Ellingsen, Christian; Fereshtehnejad, Seyed-Mohammad; Gissler, Mika; Hadkhale, Kishor; Havmoeller, Rasmus; Johansson, Lars; Juliusson, Petur Benedikt; Kiadaliri, Aliasghar A.; Kisa, Sezer; Lallukka, Tea; Mekonnen, Teferi; Meretoja, Tuomo J.; Meretoja, Atte; Naghavi, Mohsen; Neupane, Subas; Nguyen, Truc Trung; Petzold, Max; Plana-Ripoll, Oleguer; Shiri, Rahman; Sigurvinsdottir, Rannveig; Skirbekk, Vegard; Skou, Søren T; Sigfusdottir, Inga Dora; Steiner, Timothy J.; Sulo, Gerhard; Truelsen, Thomas Clement; Vasankari, Tommi Juhani; Weiderpass, Elisabete; Vollset, Stein Emil; Vos, Theo; Øverland, Simon (Peer reviewed; Journal article, 2019-12-01)
      Background The Nordic countries have commonalities in gender equality, economy, welfare, and health care, but differ in culture and lifestyle, which might create country-wise health differences. This study compared life ...
    • Linear age-course effects on the associations between body mass index, triglycerides, and female breast and male liver cancer risk: An internal replication study of 800,000 individuals 

      Häggström, Christel; Jonsson, Håkan; Bjørge, Tone; Nagel, Gabriele; Manjer, Jonas; Ulmer, Hanno; Drake, Isabel; Ghaderi, Sara; Lang, Alois; Engeland, Anders; Stattin, Pär; Stocks, Tanja (Peer reviewed; Journal article, 2020)
      Apart from the consistently observed differential association between obesity and breast cancer risk by menopausal status, the associations between obesity and other metabolic imbalances with risks of cancers have not been ...
    • Long Term Association between Serum 25-Hydroxyvitamin D and Mortality in a Cohort of 4379 Men 

      Meyer, Haakon E; Støer, Nathalie; Samuelsen, Sven Ove; Blomhoff, Rune; Robsahm, Trude Eid; Brustad, Magritt; Giovannucci, Edward L; Bjørge, Tone (Peer reviewed; Journal article, 2016-03-17)
      Objective A number of observational studies have shown an inverse association between circulating 25-hydroxyvitamin D and total mortality, but a reverse J-shaped association has also been reported. In a large nested ...
    • Maternal use of folic acid and multivitamin supplements and infant risk of birth defects in Norway, 1999–2013 

      Gildestad, Trude; Bjørge, Tone; Haaland, Øystein Ariansen; Klungsøyr, Kari; Vollset, Stein Emil; Øyen, Nina (Journal article; Peer reviewed, 2020)
      The association between folic acid supplementation and birth defects other than neural tube defects (NTD) remains unclear. We used a log-binomial regression model to investigate if periconceptional folic acid and/or ...
    • Metabolic factors and the risk of small intestine cancers: Pooled study of 800 000 individuals in the metabolic syndrome and cancer project 

      Nagel, Gabriele; Bjørge, Tone; Jaensch, Andrea; Peter, Raphael Simon; Häggström, Christel; Lang, Alois; Engeland, Anders; Teleka, Stanley; Jirström, Karin; Lindquist, David; Stattin, Pär; Ulmer, Hanno; Concin, Hans; Stocks, Tanja (Journal article; Peer reviewed, 2021)
      To explore the largely unknown etiology of small intestine cancer, we examinedmetabolic factors and risk of small intestine cancer overall and by subtypes. Among404 220 women and 403 265 men in six European cohorts, we ...
    • Metabolic risk factors for esophageal squamous cell carcinoma and adenocarcinoma: a prospective study of 580 000 subjects within the Me-Can project 

      Lindkvist, Björn; Johansen, Dorthe; Stocks, Tanja; Concin, Hans; Bjørge, Tone; Almquist, Martin; Häggström, Christel; Engeland, Anders; Hallmans, Göran; Nagel, Gabriele; Jonsson, Håkan; Selmer, Randi; Ulmer, Hanno; Tretli, Steinar; Stattin, Pär; Manjer, Jonas (Peer reviewed; Journal article, 2014-02-18)
      Background: Obesity is associated with an increased risk of esophageal adenocarcinoma (EAC) and a decreased risk of esophageal squamous cell carcinoma (ESCC). However, little is known about the risk of EAC and ESCC related ...
    • Metabolic risk score and cancer risk: pooled analysis of seven cohorts 

      Stocks, Tanja; Bjørge, Tone; Ulmer, Hanno; Manjer, Jonas; Häggström, Christel; Nagel, Gabriele; Engeland, Anders; Johansen, Dorthe; Hallmans, Göran; Selmer, Randi; Concin, Hans; Tretli, Steinar; Jonsson, Håkan; Stattin, Pär (Peer reviewed; Journal article, 2015)
      Background: There are few data on the joint influence of metabolic factors on risk of separate cancers. Methods: We analysed data on body mass index, blood pressure and plasma levels of glucose, total cholesterol and ...
    • Metabolically (un)healthy obesity and risk of obesity-related cancers: a pooled study 

      Sun, Ming; Fritz, Josef; Häggström, Christel; Bjørge, Tone; Nagel, Gabriele; Manjer, Jonas; Engeland, Anders; Zitt, Emanuel; Guelpen, Bethany van; Stattin, Pär; Ulmer, Hanno; Stocks, Tanja (Journal article; Peer reviewed, 2023)
      Background Studies of obesity with or without metabolic aberrations, commonly termed metabolically unhealthy or healthy obesity, in relation to cancer risk are scarce. Methods We investigated body mass index (normal ...
    • Paternal characteristics associated with maternal periconceptional use of folic acid supplementation 

      Mortensen, Jan Helge Seglem; Øyen, Nina; Nilsen, Roy Miodini; Fomina, Tatiana; Tretli, Steinar; Bjørge, Tone (Peer reviewed; Journal article, 2018-05-30)
      Background: Maternal predictors of folic acid (FA) supplementation use to reduce offspring risk of neural tube defects are well known, while paternal determinants for maternal FA use are less known. Such knowledge is ...
    • Plasma methionine, choline, betaine, and dimethylglycine in relation to colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) 

      Nitter, Mathilde Hjelle; Norgård, Benedicte Wentzel; De Vogel, Stefan; Eussen, Simone; Meyer, Klaus; Ulvik, Arve; Ueland, Per Magne; Nygård, Ottar; Vollset, Stein Emil; Bjørge, Tone; Tjønneland, Anne; Hansen, Louise; Boutron-Ruault, Marie-Christine; Racine, Antoine; Cottet, Vanessa; Kaaks, Rudolf; Kühn, Tilman; Trichopoulou, Antonia; Bamia, Christina; Naska, Androniki; Grioni, Sara; Palli, Domenico; Panico, Salvatore; Tumino, Rosario; Vineis, Paolo; Bueno-de-Mesquita, H. Bas; Van Kranen, Henk J.; Peeters, Petra H. M.; Weiderpass, Elisabete; Dorronsoro, Miren; Jakszyn, Paula; Sánchez, María-José; Argüelles, Marcial Vicente; Huerta, José-Maria; Barricarte, Aurelio; Johansson, Matthias; Ljuslinder, Ingrid; Khaw, Kay Tee; Wareham, Nicholas J.; Freisling, Heinz; Duarte-Salles, Talita; Stepien, Magdalena; Gunter, Mark J.; Riboli, Élio B. (Peer reviewed; Journal article, 2014-08)
      Background Disturbances in one carbon metabolism may contribute to carcinogenesis by affecting methylation and synthesis of DNA. Choline and its oxidation product betaine are involved in this metabolism and can serve as ...
    • Pooled cohort study on height and risk of cancer and cancer death 

      Wiren, Sara; Häggström, Christel; Ulmer, Hanno; Manjer, Jonas; Bjørge, Tone; Nagel, Gabriele; Johansen, Dorthe; Hallmans, Göran; Engeland, Anders; Concin, Hans; Jonsson, Håkan; Selmer, Randi; Tretli, Steinar; Stocks, Tanja; Stattin, Pär (Peer reviewed; Journal article, 2013-10-31)
      Purpose: To assess the association between height and risk of cancer and cancer death. Methods: The metabolic syndrome and cancer project is a prospective pooled cohort study of 585,928 participants from seven cohorts in ...
    • Preeclampsia in pregnancy and later use of antihypertensive drugs 

      Engeland, Anders; Bjørge, Tone; Klungsøyr, Kari; Skjaerven, Rolv; Skurtveit, Svetlana; Furu, Kari (Peer reviewed; Journal article, 2015-03-18)
      We explored the association between preeclampsia and later use of antihypertensive drugs in a population-based study with data from the Medical Birth Registry of Norway and the Norwegian Prescription Database. The study ...
    • Pregnancy-related risk factors for sex cord-stromal tumours and germ cell tumours in parous women: a registry-based study 

      Sköld, Camilla; Bjørge, Tone; Ekbom, Anders; Engeland, Anders; Gissler, Mika; Grotmol, Tom; Madanat-Harjuoja, Laura-Maria; Ording, Anne Gulbech; Trabert, Britton; Tretli, Steinar; Troisi, Rebecca; Sørensen, Henrik Toft; Glimelius, Ingrid (Journal article; Peer reviewed, 2020)
      Background Non-epithelial ovarian cancers are divided into sex cord-stromal tumours (SCSTs) and germ cell tumours (GCTs). Whereas parity and other pregnancy-related factors are protective for epithelial ovarian cancer, ...
    • Prescribed drugs in 27 000 individuals after diagnosis of colorectal cancer: A population-based cohort study 

      Engeland, Anders; Ghaderi, Sara; dos-Santos-Silva, Isabel; Furu, Kari; Hjellvik, Vidar; Kvåle, Rune; Bjørge, Tone (Journal article; Peer reviewed, 2021)
      Background The prevalence of prescribed drugs in survivors of colorectal cancer (CRC) was evaluated. Methods Data from the Cancer Registry of Norway were linked to the Norwegian Prescription Database for a study ...
    • A prospective study on metabolic risk factors and gallbladder cancer in the metabolic syndrome and cancer (Me-Can) collaborative study 

      Borena, Wegene; Edlinger, Michael; Bjørge, Tone; Häggström, Christel; Lindkvist, Björn; Nagel, Gabriele; Engeland, Anders; Stocks, Tanja; Strohmaier, Susanne; Manjer, Jonas; Selmer, Randi; Tretli, Steinar; Concin, Hans; Hallmans, Göran; Jönsson, Håkan; Stattin, Pär; Ulmer, Hanno (Peer reviewed; Journal article, 2014-02-21)
      Objective: To investigate the association between metabolic risk factors (individually and in combination) and risk of gallbladder cancer (GBC). Methods: The metabolic syndrome and cancer project (Me-Can) includes cohorts ...
    • Real-world data on cervical cancer risk stratification by cytology and HPV genotype to inform the management of HPV-positive women in routine cervical screening 

      Hashim, Dana; Engesæter, Birgit Øvstebø; Skare, Gry Baadstrand; Castle, Philip E.; Bjørge, Tone; Trope, Ameli; Nygård, Mari (Journal article; Peer reviewed, 2020)
      Background HPV16/18 detection may improve cervical cancer risk stratification and better guide which HPV-positive women warrant immediate colposcopy/biopsy. We estimated risks of cervical precancer and cancer by HPV ...
    • Reproduction and marriage among male survivors of cancer in childhood, adolescence and young adulthood: a national cohort study 

      Gunnes, Maria Winther; Lie, Rolv Terje; Bjørge, Tone; Ghaderi, Sara; Ruud, Ellen; Syse, Astri; Moster, Dag (Peer reviewed; Journal article, 2016)
      Background: Increased survival after cancer in young age has made long-term follow-up studies of high external validity important. In this national cohort study, we explored the impact of cancer in young age on reproduction ...
    • Reproductive history and risk of colorectal adenocarcinoma in parous women: a Nordic population-based case–control study 

      Bjørge, Tone; Gissler, Mika; Ording, Anne Gulbech; Engeland, Anders; Glimelius, Ingrid; Leinonen, Maarit; Sørensen, Henrik Toft; Tretli, Steinar; Ekbom, Anders; Troisi, Rebecca; Grotmol, Tom (Peer reviewed; Journal article, 2016-10-04)
      Background: Data are conflicting regarding the role of endogenous sex hormones in colorectal carcinogenesis. In this large population-based study, we pooled data from birth and cancer registries in four Nordic countries, ...
    • Risk of diabetes after gestational diabetes and preeclampsia. A registry-based study of 230,000 women in Norway 

      Engeland, Anders; Bjørge, Tone; Daltveit, Anne Kjersti; Skurtveit, Svetlana; Vangen, Siri; Vollset, Stein Emil; Furu, Kari (Peer reviewed; Journal article, 2011-02-06)
      This study aimed to use a population-based Prescription Database to explore later development of diabetes in women registered with gestational diabetes mellitus (GDM) and/or preeclampsia in the Medical Birth Registry of ...
    • The role of pregnancy in maternal cancer risk: Epidemiologic evidence from the Nordic Countries Linked Birth and Cancer Registries Cohort Project 

      Troisi, Rebecca; Glimelius, Ingrid; Grotmol, Tom; Gissler, Mika; Kitahara, Cari M.; Ording, Anne Gulbech; Sæther, Solbjørg Makalani Myrtveit; Sköld, Camilla; Sørensen, Henrik Toft; Trabert, Britton; Bjørge, Tone (Journal article; Peer reviewed, 2022)
      The experience of pregnancy has a lasting impact, in many cases beneficial, on cancer risk in the mother. In the long term, breast, ovarian, and endometrial cancers are lower in parous women, and each pregnancy provides ...