Blar i Bergen Open Research Archive på forfatter "Blomberg, Bjørn"
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Fluoroquinolone resistance among fecal extended spectrum βeta lactamases positive Enterobacterales isolates from children in Dar es Salaam, Tanzania
Kibwana, Upendo O.; Manyahi, Joel; Sandnes, Helene Heitmann; Blomberg, Bjørn; Mshana, Stephen E.; Langeland, Nina; Roberts, Adam P.; Moyo, Sabrina John (Journal article; Peer reviewed, 2023-03-07)Background: Fluoroquinolones have been, and continue to be, routinely used for treatment of many bacterial infections. In recent years, most parts of the world have reported an increasing trend of fluoroquinolone resistant ... -
Gastrointestinal colonization of extended-spectrum beta-lactamase-producing bacteria among children below five years of age hospitalized with fever in Dar es Salaam, Tanzania
Kibwana, Upendo O.; Manyahi, Joel; Sandnes, Helene Heitmann; Blomberg, Bjørn; Mshana, Stephen E.; Langeland, Nina; Moyo, Sabrina John (Journal article; Peer reviewed, 2022)Objectives: Gastrointestinal colonization of extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-PE) is of concern because prior colonization increases risk for subsequent infections. To date, the link between ... -
Genetic determinants of macrolide and tetracycline resistance in penicillin non-susceptible Streptococcus pneumoniae isolates from people living with HIV in Dar es Salaam, Tanzania
Manyahi, Joel; Moyo, Sabrina John; Langeland, Nina; Blomberg, Bjørn (Journal article; Peer reviewed, 2023-02-20)Background: Over one million yearly deaths are attributable to Streptococcus pneumoniae and people living with HIV are particularly vulnerable. Emerging penicillin non-susceptible Streptococcus pneumoniae (PNSP) challenges ... -
Genetic diversity of circulating rotavirus strains in Tanzania prior to the introduction of vaccination
Moyo, Sabrina John; Blomberg, Bjørn; Hanevik, Kurt; Kommedal, Øyvind; Vainio, Kirsti; Maselle, Samwel Y.; Langeland, Nina (Peer reviewed; Journal article, 2014-05-20)Background: Tanzania currently rolls out vaccination against rotavirus-diarrhea, a major cause of child illness and death. As the vaccine covers a limited number of rotavirus variants, this study describes the molecular ... -
Genetic relatedness and risk factor analysis of ampicillin-resistant and high-level gentamicin-resistant enterococci causing bloodstream infections in Tanzanian children
Aamodt, Håvard; Mohn, Stein Christian; Maselle, Samuel Y; Manji, Karim P.; Willems, Rob; Jureen, Roland; Langeland, Nina; Blomberg, Bjørn (Peer reviewed; Journal article, 2015-02-28)Background While enterococci resistant to multiple antimicrobials are spreading in hospitals worldwide, causing urinary tract, wound and bloodstream infections, there is little published data on these infections from Africa. ... -
Hemophagocytic lymphohistiocytosis and miliary tuberculosis in a previously healthy individual: a case report
Trovik, Linn; Sandnes, Miriam; Blomberg, Bjørn; Holmaas, Gunhild; Ahmed, Aymen B.; Tvedt, Tor Henrik Anderson; Vintermyr, Olav Karsten; Reikvam, Håkon (Journal article; Peer reviewed, 2020)Background Hemophagocytic lymphohistiocytosis (HLH) is a rare heterogenous genetic or acquired hyperinflammatory syndrome associated with a high degree of morbidity and mortality. HLH has clinical manifestations related ... -
High prevalence of faecal carriage of ESBL-producing enterobacteriaceae among children in Dar es Salaam, Tanzania
Tellevik, Marit Gjerde; Blomberg, Bjørn; Kommedal, Øyvind; Maselle, Samuel Y; Langeland, Nina; Moyo, Sabrina John (Peer reviewed; Journal article, 2016-12-09)Background: Faecal carriage of ESBL-producing bacteria is a potential risk for transmission and infection. Little is known about faecal carriage of antibiotic resistance in Tanzania. This study aimed to investigate the ... -
High prevalence of fecal carriage of extended spectrum β-lactamase-producing enterobacteriaceae among newly HIV-diagnosed adults in a community setting in Tanzania
Manyahi, Joel; Moyo, Sabrina John; Tellevik, Marit Gjerde; Langeland, Nina; Blomberg, Bjørn (Journal article; Peer reviewed, 2020)Colonization in HIV-infected populations with extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-PE) is particularly worrisome in low-income settings. This study describes the prevalence of ESBL-PE carriage ... -
High rate of antimicrobial resistance and multiple mutations in the dihydrofolate reductase gene among Streptococcus pneumoniae isolated from HIV-infected adults in a community setting in Tanzania
Manyahi, Joel; Moyo, Sabrina John; Aboud, Said; Langeland, Nina; Blomberg, Bjørn (Journal article; Peer reviewed, 2020)Objectives: The aim of this study was to characterize molecular mechanisms of resistance to trimethoprim and other antibiotics in Streptococcus pneumoniae isolates from HIV-infected adults in Dar es Salaam, Tanzania. Methods: ... -
Horizontal plasmid transfer among klebsiella pneumoniae isolates is the key factor for dissemination of extended-spectrum β-lactamases among children in Tanzania
Pedersen, Torunn Annie; Tellevik, Marit Gjerde; Kommedal, Øyvind; Lindemann, Paul Christoffer; Moyo, Sabrina John; James Peter, Jessin Janice; Blomberg, Bjørn; Samuelsen, Ørjan; Langeland, Nina (Journal article; Peer reviewed, 2020)Increased knowledge about the role of horizontal gene transfer is key to improve our understanding of the spread of antimicrobial resistance (AMR) in human populations. We therefore studied the dissemination of the blaCTX-M-15 ... -
Introducing post-discharge malaria chemoprevention (PMC) for management of severe anemia in Malawian children: a qualitative study of community health workers’ perceptions and motivation
Nkosi-Gondwe, Thandile; Robberstad, Bjarne; Blomberg, Bjørn; Phiri, Kamija S.; Lange, Siri (Journal article; Peer reviewed, 2018-12-19)Severe malarial anaemia is one of the leading causes of paediatric hospital admissions in Malawi. Post-discharge malaria chemoprevention (PMC) is the intermittent administration of full treatment courses of antimalarial ... -
Leishmaniasis i Norge
Muller, Karl Erik; Blomberg, Bjørn; Tellevik, Marit Gjerde; Jensenius, Mogens; Fladeby, Cathrine; Lier, Tore; Sand, Geir; Hannula, Raisa; Langeland, Nina; Mørch, Kristine (Journal article; Peer reviewed, 2021)Bakgrunn: Leishmaniasis er en sjelden, men potensielt alvorlig tropisk infeksjonssykdom. Norske klinikere er lite kjent med diagnostikk og behandling av denne sykdommen. Formålet med studien var å undersøke forekomst, ... -
Long COVID in a prospective cohort of home-isolated patients
Blomberg, Bjørn; Mohn, Kristin Greve-Isdahl; Brokstad, Karl Albert; Zhou, Fan; Linchausen, Dagrunn Waag; Hansen, Bernt-Are; Jalloh, Sarah Larteley Lartey; Onyango, Therese Bredholt; Kuwelker, Kanika; Sævik, Marianne; Bartsch, Hauke; Tøndel, Camilla; Kittang, Bård Reiakvam; Cox, Rebecca Jane; Langeland, Nina (Journal article; Peer reviewed, 2021)Long-term complications after coronavirus disease 2019 (COVID-19) are common in hospitalized patients, but the spectrum of symptoms in milder cases needs further investigation. We conducted a long-term follow-up in a ... -
Lower antibiotic prescription rates in hospitalized COVID-19 patients than influenza patients, a prospective study
Fjelltveit, Elisabeth Berg; Cox, Rebecca Jane; Kittang, Bård Reiakvam; Blomberg, Bjørn; Buanes, Eirik A.; Langeland, Nina; Mohn, Kristin Greve-Isdahl (Journal article; Peer reviewed, 2022)Background COVID-19 patients are extensively treated with antibiotics despite few bacterial complications. We aimed to study antibiotic use in hospitalized COVID-19 patients compared to influenza patients in two consecutive ... -
Malaria prevalence among patients with acute undifferentiated fever in secondary hospitals in India
Haanshuus, Christel Gill; Vivek, Rosario; Xena, Deepika; Chandy, Sara; Mathai, Dilip; Manoharan, Anand; Langeland, Nina; Blomberg, Bjørn; Mørch, Kristine (Conference poster, 2014-09-22) -
Malaria prevalence and performance of diagnostic tests among patients hospitalized with acute undifferentiated fever in Zanzibar
Onken, Annette; Haanshuus, Christel Gill; Miraji, Mohammed Khamis; Marijani, Msafiri; Kibwana, Kibwana Omar; Abeid, Khamis Ali; Mørch, Kristine; Reimers, Marianne; Langeland, Nina; Müller, Fredrik; Jenum, Pål; Blomberg, Bjørn (Journal article; Peer reviewed, 2022-02-19)Background: Control efforts in Zanzibar reduced the burden of malaria substantially from 2000 to 2015, but re-emergence of falciparum malaria has been observed lately. This study evaluated the prevalence of malaria and ... -
Molecular characterisation of the first New Delhi metallo-β-lactamase 1-producing Acinetobacter baumannii from Tanzania
Moyo, Sabrina John; Manyahi, Joel; Hubbard, Alasdair T. M; Byrne, Rachel L; Masoud, Nahya Salim; Aboud, Said; Manji, Karim; Blomberg, Bjørn; Langeland, Nina; Roberts, Adam P. (Journal article; Peer reviewed, 2021)Background We aimed to characterise the genetic determinants and context of two meropenem-resistant clinical isolates of Acinetobacter baumannii isolated from children hospitalised with bloodstream infections in Dar es ... -
Mortality among extrapulmonary tuberculosis patients in the HIV endemic setting: lessons from a tertiary level hospital in Mbeya, Tanzania
Grønningen, Erlend; Nanyaro, Marywinnie; Blomberg, Bjørn; Hassan, Shoaib; Ngadaya, Esther Stanslaus; Mustafa, Tehmina (Journal article; Peer reviewed, 2024)Extrapulmonary tuberculosis (EPTB) has received less attention than pulmonary tuberculosis due to its non-contagious nature. EPTB can affect any organ and is more prevalent in people living with HIV. Low- and middle-income ... -
No asymptomatic malaria parasitaemia found among 108 young children at one health facility in Dar es Salaam, Tanzania
Strøm, Gro Elizabeth Ann; Tellevik, Marit Gjerde; Fataki, Maulidi; Langeland, Nina; Blomberg, Bjørn (Peer reviewed; Journal article, 2013-11-14)Background: Asymptomatic malaria parasitaemia has been reported in areas with high malaria transmission. It may serve as a reservoir for continued transmission, and furthermore complicates diagnostics, as not all individuals ... -
Nosocomial outbreak of neonatal Salmonella enterica serotype Enteritidis meningitis in a rural hospital in northern Tanzania
Vaagland, Hogne; Blomberg, Bjørn; Krüger, Carsten; Naman, Naftali; Jureen, Roland; Langeland, Nina (Peer reviewed; Journal article, 2007-09-14)Background: Clinicians at Haydom Lutheran Hospital, a rural hospital in northern Tanzania noted an unusually high case-fatality rate of pediatric meningitis and suspected an outbreak of an unknown agent or an organism ...