Blar i Bergen Open Research Archive på forfatter "Bramham, Clive R."
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Sleep and protein synthesis-dependent synaptic plasticity: impacts of sleep loss and stress
Grønli, Janne; Soule, Jonathan; Bramham, Clive R. (Peer reviewed; Journal article, 2014-01-21)Sleep has been ascribed a critical role in cognitive functioning. Several lines of evidence implicate sleep in the consolidation of synaptic plasticity and long-term memory. Stress disrupts sleep while impairing synaptic ... -
Stimulation-induced expression of immediate early gene proteins in the dorsal horn is increased in neuropathy
Bojovic, Ognjen; Bramham, Clive R.; Tjølsen, Arne (Peer reviewed; Journal article, 2016-01)Background and aims: Peripheral neuropathic pain is described as a pain state caused by an injury or dysfunction of the nervous system, and could have clinical manifestations such as hyperalgesia, allodynia and spontaneous ... -
Two-stage translational control of dentate gyrus LTP consolidation is mediated by sustained BDNF-TrkB signaling to MNK
Panja, Debabrata; Kenney, Justin W.; D'Andrea, Laura; Zalfa, Francesca; Vedeler, Anni; Wibrand, Karin; Fukunaga, Rikiro; Bagni, Claudia; Proud, Christopher G.; Bramham, Clive R. (Peer reviewed; Journal article, 2014-11-20)BDNF signaling contributes to protein-synthesis-dependent synaptic plasticity, but the dynamics of TrkB signaling and mechanisms of translation have not been defined. Here, we show that long-term potentiation (LTP) ... -
Widespread promoter methylation of synaptic plasticity genes in long-term potentiation in the adult brain in vivo.
Maag, Jesper L.V.; Kaczorowski, Dominik C.; Panja, Debabrata; Peters, Timothy J.; Bramham, Clive R.; Wibrand, Karin; Dinger, Marcel E. (Peer reviewed; Journal article, 2017-03-23)Background: DNA methylation is a key modulator of gene expression in mammalian development and cellular differentiation, including neurons. To date, the role of DNA modifications in long-term potentiation (LTP) has not ...