Blar i Bergen Open Research Archive på forfatter "Dankel, Simon N"
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Relationship between Ketones, Ghrelin, and, Appetite on Isocaloric Diets with Varying Carbohydrate Quality and Amount: Results from a Randomized Controlled Trial in People with Obesity (CARBFUNC)
Horn, Cathrine; Gjerde, Eirin Semb; Laupsa-Borge, Johnny; Andersen, Amanda Iselin Olesen; Lawrence-Archer, Laurence; McCann, Adrian; Hansson, Patrik; Raza, Ghulam S.; Herzig, Karl Heinz; Lied, Gülen Arslan; Alho Letra Martins, Catia Patricia; Mellgren, Gunnar; Dierkes, Jutta; Dankel, Simon N (Journal article; Peer reviewed, 2023)Background Low-carbohydrate high-fat (LCHF) diets may suppress the increase in appetite otherwise seen after diet-induced fat loss. However, studies of diets without severe energy restriction are lacking, and the effects ... -
The Rho GTPase RND3 regulates adipocyte lipolysis
Dankel, Simon N; Røst, Therese Halvorsen; Kulyté, Agné; Fandalyuk, Zinayida; Skurk, Thomas; Hauner, Hans; Sagen, Jørn V.; Rydén, Mikael; Arner, Peter; Mellgren, Gunnar (Peer reviewed; Journal article, 2019)Background: Adipose tissue plays a crucial role in diet- and obesity-related insulin resistance, with implications for several metabolic diseases. Identification of novel target genes and mechanisms that regulate adipocyte ... -
Role of the Neutral Amino Acid Transporter SLC7A10 in Adipocyte Lipid Storage, Obesity and Insulin Resistance
Jersin, Regine Åsen; Tallapragada, Divya Sri Priyanka; Madsen, André; Skartveit, Linn; Fjære, Even; McCann, Adrian; Dyer, Laurence; Willems, Aron; Bjune, Jan-Inge; Bjune, Mona Synnøve; Våge, Villy; Nielsen, Hans Jørgen; Thorsen, Håvard Luong; Nedrebø, Bjørn Gunnar; Busch, Christian; Steen, Vidar M.; Blüher, Matthias; Jacobson, Peter; Svensson, Per-Arne; Fernø, Johan; Rydén, Mikael; Arner, Peter; Nygård, Ottar; Claussnitzer, Melina; Ellingsen, Ståle; Madsen, Lise; Sagen, Jørn V.; Mellgren, Gunnar; Dankel, Simon N (Journal article; Peer reviewed, 2021)Elucidation of mechanisms that govern lipid storage, oxidative stress, and insulin resistance may lead to improved therapeutic options for type 2 diabetes and other obesity-related diseases. Here, we find that adipose ... -
Seven-year trajectories of body weight, quality of life and comorbidities following Roux-en-Y gastric bypass and sleeve gastrectomy
Nielsen, Hans Jørgen; Nedrebø, Bjørn Gunnar; Fosså, Alexander; Andersen, John Roger; Assmus, Jörg; Dagsland, Vigdis Halvorsen; Dankel, Simon N; Gudbrandsen, Oddrun Anita; Fernø, Johan; Hjellestad, Iren Drange; Hjermstad, Marianne Jensen; Kolotkin, Ronette Loganzo; Thorsen, Håvard Luong; Mellgren, Gunnar; Flølo, Tone Nygaard (Journal article; Peer reviewed, 2022)Background/objectives There is limited long-term data comparing the outcomes of sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB) for severe obesity, both with respect to body weight, quality of life (QOL) and ... -
Sex-specific responses in glucose-insulin homeostasis and lipoprotein-lipid components after high-dose supplementation with marine n-3 PUFAs in abdominal obesity: a randomized double-blind crossover study
Laupsa-Borge, Johnny; Grytten, Elise; Bohov, Pavol; Bjørndal, Bodil; Strand, Elin; SKORVE, JON; Nordrehaug, Jan Erik; Berge, Rolf Kristian; Rostrup, Espen; Mellgren, Gunnar; Dankel, Simon N; Nygård, Ottar Kjell (Journal article; Peer reviewed, 2023)Background: Clinical studies on effects of marine-derived omega-3 (n-3) polyunsaturated fatty acids (PUFAs), mainly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), and the plant-derived omega-6 (n-6) PUFA ... -
Short-term effects of Vertical sleeve gastrectomy and Roux-en-Y gastric bypass on glucose homeostasis
Gudbrandsen, Oddrun Anita; Dankel, Simon N; Skumsnes, Lillian; Flølo, Tone Nygaard; Folkestad, Oddry H; Nielsen, Hans Jørgen; Våge, Villy; Mohn, Arne-Christian; Nedrebø, Bjørn Gunnar; Sagen, Jørn V.; Fernø, Johan; Mellgren, Gunnar (Peer reviewed; Journal article, 2019-10-15)The objective of this study was to compare the biochemical changes related to glucose tolerance and lipid metabolism in non-diabetic patients shortly after vertical sleeve gastrectomy (SG) or Roux-en-Y gastric bypass (RYGB). ... -
Switch from stress response to homeobox transcription factors in Adipose tissue after profound fat loss
Dankel, Simon N; Fadnes, Dag J.; Stavrum, Anne-Kristin; Stansberg, Christine; Holdhus, Rita; Hoang, Tuyen Thi Van; Veum, Vivian L.; Christensen, Bjørn Jostein; Våge, Villy; Sagen, Jørn V.; Steen, Vidar Martin; Mellgren, Gunnar (Peer reviewed; Journal article, 2010-06-09)Background In obesity, impaired adipose tissue function may promote secondary disease through ectopic lipid accumulation and excess release of adipokines, resulting in systemic low-grade inflammation, insulin resistance ... -
Ultraprosessert mat burde være et kostråd: JA
Dankel, Simon N; Molin, Marianne; Bere, Elling Tufte (Journal article, 2023)