Blar i Bergen Open Research Archive på forfatter "Dickstein, Kenneth"
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Neutrophil-to-lymphocyte ratio and outcomes in patients with new-onset or worsening heart failure with reduced and preserved ejection fraction
Curran, Fraser M.; Bhalraam, U.; Mohan, Mohapradeep; Singh, Jagdeep S.; Anker, Stefan D.; Dickstein, Kenneth; Doney, Alexander S.; Filippatos, Gerasimos; George, Jacob; Metra, Marco; Ng, Leong L.; Palmer, Colin N.; Samani, Nilesh J.; van Veldhuisen, Dirk J.; Voors, Adriaan A.; Lang, Chim C.; Mordi, Ify R. (Journal article; Peer reviewed, 2021)Aims Inflammation is thought to play a role in heart failure (HF) pathophysiology. Neutrophil-to-lymphocyte ratio (NLR) is a simple, routinely available measure of inflammation. Its relationship with other inflammatory ... -
Pathophysiological pathways in patients with heart failure and atrial fibrillation
Santema, Bernadet T.; Arita, Vicente Artola; Sama, Iziah E.; Kloosterman, Mariëlle; van den Berg, Maarten P.; Nienhuis, Hans L.A.; Van Gelder, Isabelle C.; van der Meer, Peter; Zannad, Faiez; Metra, Marco; Ter Maaten, Jozine M.; Cleland, John G.; Ng, Leong L.; Anker, Stefan D.; Lang, Chim C.; Samani, Nilesh J.; Dickstein, Kenneth; Filippatos, Gerasimos; van Veldhuisen, Dirk J.; Lam, Carolyn S.P.; Rienstra, Michiel; Voors, Adriaan A. (Journal article; Peer reviewed, 2022)Aims Atrial fibrillation (AF) and heart failure (HF) are two growing epidemics that frequently co-exist. We aimed to gain insights into the underlying pathophysiological pathways in HF patients with AF by comparing ... -
Pathophysiological pathways related to high plasma growth differentiation factor 15 concentrations in patients with heart failure
Ceelen, Daan; Voors, Adriaan A.; Tromp, Jasper; van Veldhuisen, Dirk J.; Dickstein, Kenneth; de Boer, Rudolf A.; Lang, Chim C.; Anker, Stefan D.; Ng, Leong L.; Metra, Marco; Ponikowski, Piotr; Figarska, Sylwia M. (Journal article; Peer reviewed, 2022)Aims Elevated concentrations of growth differentiation factor 15 (GDF-15) in patients with heart failure (HF) have been consistently associated with worse clinical outcomes, but what disease mechanisms high GDF-15 ... -
The patient perspective: Quality of life in advanced heart failure with frequent hospitalisations
Nieminen, Markku S.; Dickstein, Kenneth; Fonseca, Cândida; Serrano, Jose Magaña; Parissis, John; Fedele, Francesco; Wikström, Gerhard; Agostoni, Piergiuseppe; Atar, Shaul; Baholli, Loant; Brito, Dulce; Colet, Josep Comin; Édes, István Ferenc; Gómez Mesa, Juan E.; Gorjup, Vojka; Garza, Eduardo Herrera; González Juanatey, José R.; Karanovic, Nenad; Karavidas, Apostolos; Katsytadze, Igor; Kivikko, Matti; Matskeplishvili, Simon; Merkely, Béla; Morandi, Fabrizio; Novoa, Angel; Oliva, Fabrizio; Ostadal, Petr; Pereira-Barretto, Antonio; Pollesello, Piero; Rudiger, Alain; Schwinger, Robert HG; Wieser, Manfred; Yavelov, Igor; Zymlinski, Robert (Peer reviewed; Journal article, 2015-07-15)End of life is an unfortunate but inevitable phase of the heart failure patients' journey. It is often preceded by a stage in the progression of heart failure defined as advanced heart failure, and characterised by poor ... -
Perceived risk profile and treatment optimization in heart failure: an analysis from BIOlogy Study to TAilored Treatment in chronic heart failure
Kobayashi, Masatake; Voors, Adriaan A.; Ouwerkerk, Wouter; Duarte, Kevin; Girerd, Nicolas; Rossignol, Patrick; Metra, Marco; Lang, Chim C.; Ng, Leong L.; Filippatos, Gerasimos; Dickstein, Kenneth; van Veldhuisen, Dirk J.; Zannad, Faiez; Ferreira, João Pedro (Journal article; Peer reviewed, 2021)Background Achieving target doses of angiotensin-converting-enzyme inhibitor/angiotensin-receptor blockers (ACEi/ARB) and beta-blockers in heart failure with reduced ejection fraction (HFrEF) is often underperformed. In ... -
Quality of life in men and women with heart failure: association with outcome, and comparison between the Kansas City Cardiomyopathy Questionnaire and the EuroQol 5 dimensions questionnaire
Ravera, Alice; Santema, Bernadet T.; Sama, Iziah E.; Meyer, Sven; Lombardi, Carlo; Carubelli, Valentina; Ferreira, João Pedro; Lang, Chim C.; Dickstein, Kenneth; Anker, Stefan D.; Samani, Nilesh J.; Zannad, Faiez; van Veldhuisen, Dirk J.; Teerlink, John R.; Metra, Marco; Voors, Adriaan A. (Journal article; Peer reviewed, 2021)Aims We sought to analyse quality of life (QoL) measures derived from two questionnaires widely used in clinical trials, the Kansas City Cardiomyopathy Questionnaire (KCCQ) and the EuroQoL 5 dimensions (EQ-5D), and to ... -
Repetitive use of levosimendan for treatment of chronic advanced heart failure: Clinical evidence, practical considerations, and perspectives: An expert panel consensus
Nieminen, Markku Sakari; Altenberger, Johann; Ben-Gal, Tuvia; Böhmer, Armin; Comin-Colet, Josep; Dickstein, Kenneth; Édes, István Ferenc; Fedele, Francesco; Fonseca, Cândida; García-González, Martín J.; Giannakoulas, Georgios A.; Iakobishvili, Zaza; Jääskeläinen, Pertti; Karavidas, Apostolos I.; Kettner, Jiří; Kivikko, Matti; Lund, Lars H.; Matskeplishvili, Simon T.; Metra, Marco; Morandi, Fabrizio; Oliva, Fabrízio A.; Parkhomenko, Alexander; Parissis, John T.; Pollesello, Piero; Pölzl, Gerhard; Schwinger, Robert H.G.; Segovia, Javier; Seidel, Monika; Vrtovec, Bojan; Wikström, Gerhard (Peer reviewed; Journal article, 2014-06-15)Background The intravenous inodilator levosimendan was developed for the treatment of patients with acutely decompensated heart failure. In the last decade scientific and clinical interest has arisen for its repetitive or ... -
Risk estimates of imminent cardiovascular death and heart failure hospitalization are improved using serial natriuretic peptide measurements in patients With coronary artery disease and type 2 diabetes
Wolsk, Emil; Claggett, Brian; Diaz, Rafael; Dickstein, Kenneth; Gerstein, Hertzel C.; Køber, Lars; Lewis, Eldrin F.; Maggioni, Aldo P.; McMurray, John J.V.; Probstfield, Jeffrey L.; Riddle, Matthew C.; Solomon, Scott D.; Tardif, Jean-Claude; Pfeffer, Marc A. (Journal article; Peer reviewed, 2022)Background: Baseline and temporal changes in natriuretic peptide (NP) concentrations have strong prognostic value with regard to long‐term cardiovascular risk stratification. To increase the clinical utility of NP sampling ... -
Sexual dimorphism in selenium deficiency is associated with metabolic syndrome and prevalence of heart disease
Weening, Eerde H.; Al-Mubarak, Ali A.; Dokter, Martin M.; Dickstein, Kenneth; Lang, Chim C.; Ng, Leong L.; Metra, Marco; van Veldhuisen, Dirk J.; Touw, Daan J.; de Boer, Rudolf A.; Gansevoort, Ron T.; Voors, Adriaan A.; Bakker, Stephan J. L.; van der Meer, Peter; Bomer, Nils (Journal article; Peer reviewed, 2023)Background Serum selenium levels have been associated with the incidence of heart failure (HF) and signs of the metabolic syndrome. In addition, notable differences have been reported between males and females in food ... -
Systemic oxidative stress associates with disease severity and outcome in patients with new-onset or worsening heart failure
de Koning, Marie-Sophie L. Y.; Emmens, Johanna E.; Romero-Hernández, Esteban; Bourgonje, Arno R.; Assa, Solmaz; Figarska, Sylwia M.; Cleland, John G. F.; Samani, Nilesh J.; Ng, Leong L.; Lang, Chim C.; Metra, Marco; Filippatos, Gerasimos S.; van Veldhuisen, Dirk J.; Anker, Stefan D.; Dickstein, Kenneth; Voors, Adriaan A.; Lipsic, Erik; van Goor, Harry; van der Harst, Pim (Journal article; Peer reviewed, 2023)Background: Oxidative stress may be a key pathophysiological mediator in the development and progression of heart failure (HF). The role of serum-free thiol concentrations, as a marker of systemic oxidative stress, in HF ... -
Upgrades from Previous Cardiac Implantable Electronic Devices Compared to De Novo Cardiac Resynchronization Therapy Implantations: Results from CRT Survey-II in the Turkish Population
Koçyiğit, Duygu; Sarıgül, Nedim Umutay; Altın, Timuçin; Çay, Serkan; Normand, Camilla Jacqueline Hansine; Linde, Cecilia; Dickstein, Kenneth (Journal article; Peer reviewed, 2022)Objective: Cardiac resynchronization therapy is the guideline-directed treatment option in selected heart failure with reduced left ventricular ejection fraction patients. Data regarding the contemporary clinical practice ... -
Urinary Marker Profiles in Heart Failure with Reduced Versus Preserved Ejection Fraction
Streng, Koen W.; Hillege, Hans L.; ter Maaten, Jozine M.; van Veldhuisen, Dirk J.; Dickstein, Kenneth; Samani, Nilesh J.; Ng, Leong L.; Metra, Marco; Filippatos, Gerasimos S.; Ponikowski, Piotr; Zannad, Faiez; Anker, Stefan D.; van der Meer, Peter; Lang, Chim C.; Voors, Adriaan A.; Damman, Kevin (Journal article; Peer reviewed, 2023)Background Recent data suggest different causes of renal dysfunction between heart failure with reduced (HFrEF) versus preserved ejection fraction (HFpEF). We therefore studied a wide range of urinary markers reflecting ... -
The value of spot urinary creatinine as a marker of muscle wasting in patients with new-onset or worsening heart failure
Pandhi, Paloma; Streng, Koen W.; Anker, Stefan D.; Cleland, John G.; Damman, Kevin; Dickstein, Kenneth; Pellicori, Pierpaolo; Lang, Chim C.; Ng, Leong; Samani, Nilesh J.; Zannad, Faiez; Metra, Marco; Rossignol, Patrick; Filippatos, Gerasimos; van Veldhuisen, Dirk J.; Voors, Adriaan A.; ter Maaten, Jozine M. (Journal article; Peer reviewed, 2021)Background Muscle wasting and unintentional weight loss (cachexia) have been associated with worse outcomes in heart failure (HF), but timely identification of these adverse phenomena is difficult. Spot urinary creatinine ...