Browsing Bergen Open Research Archive by Author "Gilhus, Nils Erik"
Now showing items 21-40 of 40
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Perinatal Depression and Anxiety in Women with Multiple Sclerosis: A Population-Based Cohort Study
Eid, Karine; Torkildsen, Øivind Fredvik Grytten; Aarseth, Jan Harald; Flemmen, Heidi Øyen; Holmøy, Trygve; Lorentzen, Åslaug Rudjord; Myhr, Kjell-Morten; Riise, Trond; Simonsen, Cecilia Smith; Torkildsen, Cecilie Fredvik; Wergeland, Stig; Willumsen, Johannes Sverre; Øksendal, Nina; Gilhus, Nils Erik; Bjørk, Marte-Helene (Journal article; Peer reviewed, 2021)Objective: To assess the occurrence of perinatal depression and anxiety in women before and after diagnosis of multiple sclerosis (MS). Methods: 114,629 pregnant women were included in the Norwegian Mother, Father and Child ... -
Physical training and exercise in myasthenia gravis
Gilhus, Nils Erik (Journal article; Peer reviewed, 2021)Myasthenia gravis is characterized by muscle weakness and fatigue. As sustained muscle use increases the weakness, the value of physical training programs has previously been questioned. This is a review to clarify the ... -
Plasma unmetabolized folic acid in pregnancy and risk of autistic traits and language impairment in antiseizure medication-exposed children of women with epilepsy
Husebye, Elisabeth Synnøve Nilsen; Wendel, Annabel Willemijn Karine; Gilhus, Nils Erik; Riedel, Bettina Maria Ingeborg; Bjørk, Marte-Helene (Journal article; Peer reviewed, 2022)Background: Fetal exposure to unmetabolized folic acid (UMFA) during pregnancy may be associated with adverse neurodevelopment. Antiseizure medication (ASM) may interact with folate metabolism. Women with epilepsy using ... -
Polio and post-polio syndrome in non-Western immigrants: A new challenge for the healthcare system in Norway
Festvåg, Lillian; Stanghelle, Johan K; Gilhus, Nils Erik; Rike, Per-Ola; Schanke, Anne-Kristine (Peer reviewed; Journal article, 2019)Objective: To explore the health situation and identify specific health challenges in non-Western immigrants with polio in Norway, by comparing their status with Western immigrants with polio and native Norwegians with ... -
Pregnancy, folic acid, and antiseizure medication
Bjørk, Marte-Helene; Vegrim, Håkon Magne; Alvestad, Silje; Monsen, Anne-Lise Bjørke; Riedel, Bettina Maria Ingeborg; Gilhus, Nils Erik; Husebye, Elisabeth Synnøve Nilsen (Journal article; Peer reviewed, 2023)Background Although some antiseizure medications (ASMs) are teratogenic, most people with epilepsy need treatment in pregnancy. The risk of ASM fetotoxicity may be mitigated with folic acid. High-dose folic acid ... -
Prenatal exposure to antiseizure medications and fetal growth: a population-based cohort study from the Nordic countries
Christensen, Jakob; Zoega, Helga; Leinonen, Maarit; Gilhus, Nils Erik; Gissler, Mika; Igland, Jannicke; Sun, Yuelian; Tomson, Torbjörn; Alvestad, Silje; Bjørk, Marte-Helene; Dreier, Julie Werenberg (Journal article; Peer reviewed, 2024)Background: The short- and long-term consequences of restricted fetal growth cause considerable concern, and how prenatal exposure to different antiseizure medications (ASMs) affects fetal growth remains uncertain. Methods: ... -
Prescribing patterns for higher dose folic acid in pregnant women with epilepsy treated with antiseizure medication
Vegrim, Håkon Magne; Dreier, Julie Werenberg; Igland, Jannicke; Gilhus, Nils Erik; Alvestad, Silje; Gissler, Mika; Leinonen, Maarit; Sun, Yuelian; Zoega, Helga; Christensen, Jakob; Bjørk, Marte-Helene; Tomson, Torbjörn (Journal article; Peer reviewed, 2024)Objective: This study was undertaken to characterize the use of higher doses of folic acid (≥1 mg daily) in relation to pregnancy in Denmark, Norway, and Sweden in women with epilepsy treated with antiseizure medication ... -
Prevalence of self-reported emotional, physical, and sexual abuse and association with fear of childbirth in pregnant women with epilepsy: The Norwegian Mother, Father, and Child Cohort Study
Vederhus, Johannes; Husebye, Elisabeth Synnøve Nilsen; Eid, Karine; Gilhus, Nils Erik; Bjørk, Marte-Helene (Journal article; Peer reviewed, 2022)Objective This study was undertaken to examine the prevalence of self-reported experiences with abuse in pregnant women with epilepsy and the association between having experienced abuse and childbirth expectations, ... -
Psychiatric Comorbidity, Social Aspects and Quality of Life in a Population-Based Cohort of Expecting Fathers with Epilepsy
Reiter, Simone B. C. Frizell; Veiby, Gyri; Bjørk, Marte Helene; Engelsen, Bernt; Daltveit, Anne Kjersti; Gilhus, Nils Erik (Peer reviewed; Journal article, 2015-12-04)Objectives. To investigate psychiatric disorders, adverse social aspects and quality of life in men with epilepsy during partner’s pregnancy. Method. We used data from the Norwegian Mother and Child Cohort Study, including ... -
Repeated acetylcholine receptor antibody-concentrations and association to clinical myasthenia gravis development
Heldal, Anne Taraldsen; Eide, Geir Egil; Romi, Fredrik Robert; Owe, Jone Furulund; Gilhus, Nils Erik (Peer reviewed; Journal article, 2014-12-02)Introduction: We aimed to examine the longitudinal association between Myasthenia Gravis (MG) clinical severity and concentration of acetylcholine receptor (AChR)-antibodies to evaluate if AChR-antibody variations correlate ... -
Risk of Perinatal and Maternal Morbidity and Mortality among Pregnant Women with Epilepsy
Razaz, Neda; Igland, Jannicke; Bjørk, Marte-Helene; Joseph, K.S.; Dreier, Julie Werenberg; Gilhus, Nils Erik; Gissler, Mika; Leinonen, Maarit; Zoega, Helga; Alvestad, Silje; Christensen, Jakob; Tomson, Torbjörn (Journal article; Peer reviewed, 2024)Importance: Maternal epilepsy is associated with adverse pregnancy and neonatal outcomes. A better understanding of this condition and the associated risk of mortality and morbidity at the time of delivery could help reduce ... -
Socioeconomic differences in use of antiseizure medication in pregnancies with maternal epilepsy: A population-based study from Nordic universal health care systems
Leinonen, Maarit K.; Igland, Jannicke; Dreier, Julie Werenberg; Alvestad, Silje; Cohen, Jacqueline Mallory; Gilhus, Nils Erik; Gissler, Mika; Sun, Yuelian; Tomson, Torbjörn; Zoega, Helga; Vegrim, Håkon Magne; Christensen, Jakob; Bjørk, Marte-Helene (Journal article; Peer reviewed, 2024)Objective Research points to disparities in disease burden and access to medical care in epilepsy. We studied the association between socioeconomic status (SES) and antiseizure medication (ASM) use in pregnancies with ... -
Spike count and morphology in the classification of epileptiform discharges
Aanestad, Eivind; Gilhus, Nils Erik; Olberg, Henning Kristian; Kural, Mustafa Aykut; Beniczky, Sándor; Brøgger, Jan (Journal article; Peer reviewed, 2023)Purpose: The purpose of this study is to investigate the impact of Bergen Epileptiform Morphology Score (BEMS) and interictal epileptiform discharge (IED) candidate count in EEG classification. Methods: We included 400 ... -
Total drug treatment and comorbidity in myasthenia gravis: a population-based cohort study
Andersen, Jintana Bunpan; Owe, Jone Furulund; Engeland, Anders; Gilhus, Nils Erik (Peer reviewed; Journal article, 2014-04-09)Background and purpose: Comorbidity in myasthenia gravis (MG) is important for diagnosis, treatment and prognosis. Disease complexity was assessed by examining total drug treatment, immune therapy and comorbidity in a ... -
User Involvement in Myasthenia Gravis Research
Gilhus, Nils Erik; Hovland, Sandra Iren Barkås (Journal article; Peer reviewed, 2022-06-02) -
Using the Norwegian Mother and Child Cohort Study to determine risk factors for delayed development and neuro-psychiatric symptoms in the offspring of parents with epilepsy
Bjørk, Marte Helene; Veiby, Gyri; Spigset, Olav; Gilhus, Nils Erik (Peer reviewed; Journal article, 2014-12-29)Introduction: Antiepileptic drug (AED) teratogenicity is suspected to be the main cause of impaired development in children of women with epilepsy. However, many factors may confound the reported risks. The purpose of this ... -
Verbal abilities in children of mothers with epilepsy: Association to maternal folate status
Husebye, Elisabeth Synnøve Nilsen; Gilhus, Nils Erik; Riedel, Bettina; Spigset, Olav; Daltveit, Anne Kjersti; Bjørk, Marte-Helene (Peer reviewed; Journal article, 2018-08)Objective: To examine the effect of maternal folic acid supplementation and maternal plasma folate and antiepileptic drug (AED) concentrations on language delay in AED-exposed children of mothers with epilepsy. Methods: ... -
Vitamin B status and association with antiseizure medication in pregnant women with epilepsy
Husebye, Elisabeth Synnøve Nilsen; Riedel, Bettina Maria Ingeborg; Monsen, Anne-Lise Bjørke; Spigset, Olav; Daltveit, Anne Kjersti Nesje; Gilhus, Nils Erik; Bjørk, Marte-Helene (Journal article; Peer reviewed, 2021)Objective Antiseizure medication (ASM) use interacts with vitamin B status in nonpregnant epilepsy populations. We aimed to examine the association between ASM and vitamin B status in pregnant women with epilepsy. Methods ... -
Young people with epilepsy have an increased risk of eating disorder and poor quality diet
Kolstad, Eivind; Bjørk, Marte Helene; Gilhus, Nils Erik; Alfstad, Kristin Åshild; Clench-Aas, Jocelyne; Lossius, Morten (Peer reviewed; Journal article, 2018-03)Objective: To investigate whether adolescents with epilepsy are at increased risk of having self‐reported eating disorder symptoms and poor quality diet compared to young people from the general population. Methods: We ... -
Zilucoplan: An Investigational Complement C5 Inhibitor for the Treatment of Acetylcholine Receptor Autoantibody–Positive Generalized Myasthenia Gravis
Howard, James F.; Vissing, John; Gilhus, Nils Erik; Leite, Maria Isabel; Utsugisawa, Kimiaki; Duda, Petra W.; Farzaneh-Far, Ramin; Murai, Hiroyuki; Wiendl, Heinz (Journal article; Peer reviewed, 2021)Generalized myasthenia gravis (gMG) is an autoimmune disorder in which pathogenic autoantibodies damage the neuromuscular junction, causing disabling or life-threatening muscle weakness. Most treatments nonspecifically ...