• Early suppression policies protected pregnant women from COVID-19 in 2020: A population-based surveillance from the Nordic countries 

      Varpula, Reetta; Äyräs, Outi; Aabakke, Anna J. M.; Klungsøyr, Kari; Svanvik, Teresia; Kanerva, Julia; Jonasdottir, Eva; Mentzoni, Camilla Tjønneland; Thurn, Lars; Jones, Elin; Fredriksson, Lisa; Pettersson, Karin; Nyfløt, Lill Trine; Vangen, Siri; Røe, Kjerstine; Juliusson, Pétur B.; Källén, Karin; Gissler, Mika; Pyykönen, Aura; Jakobsson, Maija; Krebs, Lone; Engjom, Hilde Marie (Journal article; Peer reviewed, 2024)
      Introduction The Coronavirus 2019 Disease (COVID-19) pandemic reached the Nordic countries in March 2020. Public health interventions to limit viral transmission varied across different countries both in timing and in ...
    • Folic Acid and Risk of Preterm Birth, Preeclampsia, and Fetal Growth Restriction Among Women With Epilepsy A Prospective Cohort Study 

      Alvestad, Silje; Husebye, Elisabeth Synnøve Nilsen; Christensen, Jakob; Dreier, Julie Werenberg; Sun, Yuelian; Igland, Jannicke; Leinonen, Maarit; Gissler, Mika; Gilhus, Nils Erik; Tomson, Torbjörn; Bjørk, Marte-Helene (Journal article; Peer reviewed, 2022)
      Background and Objectives Women with epilepsy treated with antiseizure medication (ASM) have increased risk of pregnancy complications including preterm birth, fetal growth restriction, and preeclampsia. We aimed to ...
    • An international contrast of rates of placental abruption: An age-period-cohort analysis 

      Ananth, Cande V.; Keyes, Katherine M.; Hamilton, Ava; Gissler, Mika; Wu, Chunsen; Liu, Shiliang; Luque-Fernandez, Miguel Angel; Skjaerven, Rolv; Williams, Michelle A.; Tikkanen, Minna; Cnattingius, Sven (Peer reviewed; Journal article, 2015-05-27)
      Background: Although rare, placental abruption is implicated in disproportionately high rates of perinatal morbidity and mortality. Understanding geographic and temporal variations may provide insights into possible amenable ...
    • International versus national growth charts for identifying small and large-for-gestational age newborns: A population-based study in 15 European countries 

      Hocquette, Alice; Durox, Mélanie; Wood, Rachael; Klungsøyr, Kari; Szamotulska, Katarzyna; Berrut, Sylvan; Rihs, Tonia; Kyprianou, Theopisti; Sakkeus, Luule; Lecomte, Aline; Zile, Irisa; Alexander, Sophie; Klimont, Jeannette; Barros, Henrique; Gatt, Miriam; Isakova, Jelena; Blondel, Béatrice; Gissler, Mika; Zeitlin, Jennifer (Journal article; Peer reviewed, 2021)
      Background To inform the on-going debate about the use of universal prescriptive versus national intrauterine growth charts, we compared perinatal mortality for small and large-for-gestational-age (SGA/LGA) infants according ...
    • Life expectancy and disease burden in the Nordic countries: results from the Global Burden of Diseases, Injuries, and Risk Factors Study 2017 

      Kisa, Adnan; Knudsen, Ann Kristin; Allebeck, Peter; Tollånes, Mette Christophersen; Skogen, Jens Christoffer; Iburg, Kim Moesgaard; McGrath, John J; Juel, Knud; Agardh, Emilie Elisabet; Arnlöv, Johan; Bjørge, Tone; Carrero, Juan J.; Cederroth, Christopher R; Eggen, Anne Elise; El-Khatib, Ziad; Lycke Ellingsen, Christian; Fereshtehnejad, Seyed-Mohammad; Gissler, Mika; Hadkhale, Kishor; Havmoeller, Rasmus; Johansson, Lars; Juliusson, Petur Benedikt; Kiadaliri, Aliasghar A.; Kisa, Sezer; Lallukka, Tea; Mekonnen, Teferi; Meretoja, Tuomo J.; Meretoja, Atte; Naghavi, Mohsen; Neupane, Subas; Nguyen, Truc Trung; Petzold, Max; Plana-Ripoll, Oleguer; Shiri, Rahman; Sigurvinsdottir, Rannveig; Skirbekk, Vegard; Skou, Søren T; Sigfusdottir, Inga Dora; Steiner, Timothy J.; Sulo, Gerhard; Truelsen, Thomas Clement; Vasankari, Tommi Juhani; Weiderpass, Elisabete; Vollset, Stein Emil; Vos, Theo; Øverland, Simon (Peer reviewed; Journal article, 2019-12-01)
      Background The Nordic countries have commonalities in gender equality, economy, welfare, and health care, but differ in culture and lifestyle, which might create country-wise health differences. This study compared life ...
    • Neonatal Mortality Disparities by Gestational Age in European Countries 

      Sartorius, Victor; Philibert, Marianne; Klungsøyr, Kari; Klimont, Jeannette; Szamotulska, Katarzyna; Drausnik, Zeljka; Velebil, Petr; Mortensen, Laust; Gissler, Mika; Fresson, Jeanne; Nijhuis, Jan; Zhang, Wei-Hong; Källén, Karin; Rihs, Tonia A.; Tica, Vlad; Matthews, Ruth; Smith, Lucy; Zeitlin, Jennifer; Farr, Alex; Alexander, Sophie; Racapé, Judith; Vandervelpen, Gisèle; Coutellas, Vasos; Kyprianou, Theopisti; Jirova, Jitka; Sakkeus, Luule; Abuladze, Liili; Blondel, Béatrice; Vilain, Annick; Durox, Mélanie; Heller, Guenther; Sziller, István; Gunnarsdóttir, Johanna; Ólafsdóttir, Helga Sól; Sikora, Izabela; O'Hara, Sinead; Kearns, Karen; Cuttini, Marina; Loghi, Marzia; Boldrini, Rosaria; Pappagal, Marilena; Marchetti, Stefano; Donati, Serena; Misins, Janis; Zile-Velika, Irisa; Isakova, Jelena; Lecomte, Aline; Pastore, Jessica; Álvarez, Daniel; Gatt, Miriam; Achterberg, P.W.; Broeders, Lisa; Akerkar, Rupali Rajendra; Engjom, Hilde Marie; Mierzejewska, Ewa; Barros, Henrique; Puscasiu, Lucian; Budianu, Mihaela-Alexandra; Cucu, Alexandra; Luèovnik, Miha; Verdenik, Ivan; Elorriaga, Maria Fernandez; Zurriaga, Oscar; Alcaide, Adela Recio; Nyman, Anastasia; Macfarlane, Alison; Scott, Sonya; Monteath, Kirsten; Morgan, Siobhan; Thomas, Craig; Magill, Sinead; Ceely, Greg (Journal article; Peer reviewed, 2024)
      Importance There are wide disparities in neonatal mortality rates (NMRs, deaths <28 days of life after live birth per 1000 live births) between countries in Europe, indicating potential for improvement. Comparing ...
    • Nordic health registry-based research: A review of health care systems and key registries 

      Laugesen, Kristina; Ludvigsson, Jonas F.; Schmidt, Morten; Gissler, Mika; Valdimarsdottir, Unnur; Lunde, Astrid; Sørensen, Henrik Toft (Journal article; Peer reviewed, 2021)
      The Nordic countries are Denmark, Finland, Iceland, Norway, and Sweden and comprise a total population of approximately 27 million. The countries provide unique opportunities for joint health registry-based research in ...
    • Pregnancy-related risk factors for sex cord-stromal tumours and germ cell tumours in parous women: a registry-based study 

      Sköld, Camilla; Bjørge, Tone; Ekbom, Anders; Engeland, Anders; Gissler, Mika; Grotmol, Tom; Madanat-Harjuoja, Laura-Maria; Ording, Anne Gulbech; Trabert, Britton; Tretli, Steinar; Troisi, Rebecca; Sørensen, Henrik Toft; Glimelius, Ingrid (Journal article; Peer reviewed, 2020)
      Background Non-epithelial ovarian cancers are divided into sex cord-stromal tumours (SCSTs) and germ cell tumours (GCTs). Whereas parity and other pregnancy-related factors are protective for epithelial ovarian cancer, ...
    • Prenatal exposure to antiseizure medications and fetal growth: a population-based cohort study from the Nordic countries 

      Christensen, Jakob; Zoega, Helga; Leinonen, Maarit; Gilhus, Nils Erik; Gissler, Mika; Igland, Jannicke; Sun, Yuelian; Tomson, Torbjörn; Alvestad, Silje; Bjørk, Marte-Helene; Dreier, Julie Werenberg (Journal article; Peer reviewed, 2024)
      Background: The short- and long-term consequences of restricted fetal growth cause considerable concern, and how prenatal exposure to different antiseizure medications (ASMs) affects fetal growth remains uncertain. Methods: ...
    • Prescribing patterns for higher dose folic acid in pregnant women with epilepsy treated with antiseizure medication 

      Vegrim, Håkon Magne; Dreier, Julie Werenberg; Igland, Jannicke; Gilhus, Nils Erik; Alvestad, Silje; Gissler, Mika; Leinonen, Maarit; Sun, Yuelian; Zoega, Helga; Christensen, Jakob; Bjørk, Marte-Helene; Tomson, Torbjörn (Journal article; Peer reviewed, 2024)
      Objective: This study was undertaken to characterize the use of higher doses of folic acid (≥1 mg daily) in relation to pregnancy in Denmark, Norway, and Sweden in women with epilepsy treated with antiseizure medication ...
    • Recurrence of postpartum hemorrhage in relatives: A population-based cohort study 

      Linde, Lorentz Erland; Ebbing, Cathrine; Moster, Dag; Kessler, Jørg; Baghestan, Elham; Gissler, Mika; Rasmussen, Svein (Journal article; Peer reviewed, 2021)
      Introduction Studies on the family aggregation of postpartum hemorrhage (PPH) are scarce and with inconsistent results, and to what extent current birthweight influences recurrence between relatives remains to be studied. ...
    • Recurrence of postpartum hemorrhage, maternal and paternal contribution, and the effect of offspring birthweight and sex: a population-based cohort study 

      Linde, Lorentz Erland; Ebbing, Cathrine; Moster, Dag; Kessler, Jørg; Baghestan, Elham; Gissler, Mika; Rasmussen, Svein (Journal article; Peer reviewed, 2022)
      Purpose: This study examines individual aggregation of postpartum hemorrhage (PPH), paternal contribution and how offspring birthweight and sex influence recurrence of PPH. Further, we wanted to estimate the proportion of ...
    • Reproductive history and risk of colorectal adenocarcinoma in parous women: a Nordic population-based case–control study 

      Bjørge, Tone; Gissler, Mika; Ording, Anne Gulbech; Engeland, Anders; Glimelius, Ingrid; Leinonen, Maarit; Sørensen, Henrik Toft; Tretli, Steinar; Ekbom, Anders; Troisi, Rebecca; Grotmol, Tom (Peer reviewed; Journal article, 2016-10-04)
      Background: Data are conflicting regarding the role of endogenous sex hormones in colorectal carcinogenesis. In this large population-based study, we pooled data from birth and cancer registries in four Nordic countries, ...
    • Risk factors and recurrence of cause-specific postpartum hemorrhage: A population-based study 

      Linde, Lorentz Erland; Rasmussen, Svein; Moster, Dag; Kessler, Jørg; Baghestan, Elham; Gissler, Mika; Ebbing, Cathrine (Journal article; Peer reviewed, 2022)
      Objective To explore risk profiles of the different types of postpartum hemorrhage (PPH >500ml or severe PPH >1500ml) and their recurrence risks in a subsequent delivery. Methods With data from The Medical Birth ...
    • Risk factors for mortality in infancy and childhood in children with major congenital anomalies: A European population-based cohort study 

      Tan, Joachim; Glinianaia, Svetlana V.; Rankin, Judith; Pierini, Anna; Santoro, Michele; Coi, Alessio; Garne, Ester; Loane, Maria; Given, Joanne E.; Brigden, Joanna; Ballardini, Elisa; Cavero-Carbonell, Clara; de Walle, Hermien E. K.; García-Villodre, Laura; Gatt, Miriam; Gissler, Mika; Heino, Anna; Jordan, Sue; Khoshnood, Babak; Klungsøyr, Kari; Lelong, Nathalie; Lutke, Renée L.; Neville, Amanda J.; Tucker, David; Urhoj, Stine K.; Wellesley, Diana; Morris, Joan K. (Journal article; Peer reviewed, 2023)
      Background: Preterm birth and young maternal age are known risk factors for infant and childhood mortality. There is limited knowledge of the impact of these risk factors in children born with major congenital anomalies ...
    • Risk of Perinatal and Maternal Morbidity and Mortality among Pregnant Women with Epilepsy 

      Razaz, Neda; Igland, Jannicke; Bjørk, Marte-Helene; Joseph, K.S.; Dreier, Julie Werenberg; Gilhus, Nils Erik; Gissler, Mika; Leinonen, Maarit; Zoega, Helga; Alvestad, Silje; Christensen, Jakob; Tomson, Torbjörn (Journal article; Peer reviewed, 2024)
      Importance: Maternal epilepsy is associated with adverse pregnancy and neonatal outcomes. A better understanding of this condition and the associated risk of mortality and morbidity at the time of delivery could help reduce ...
    • Risk of stroke the year following a delivery after using assisted reproductive technologies 

      Magnus, Maria Christine; Håberg, Siri Eldevik; Rönö, Kristiina; Romundstad, Liv Bente Bergem; Bergh, Christina; Spangmose, Anne Lærke; Pinborg, Anja; Gissler, Mika; Wennerholm, Ulla-Britt; Opdahl, Signe (Journal article; Peer reviewed, 2023)
      Background Studies indicate that individuals who deliver after assisted reproductive technologies (ART) may have an increased risk of cardiovascular disease (CVD). A recent large study from the U.S. showed a higher risk ...
    • The role of pregnancy in maternal cancer risk: Epidemiologic evidence from the Nordic Countries Linked Birth and Cancer Registries Cohort Project 

      Troisi, Rebecca; Glimelius, Ingrid; Grotmol, Tom; Gissler, Mika; Kitahara, Cari M.; Ording, Anne Gulbech; Sæther, Solbjørg Makalani Myrtveit; Sköld, Camilla; Sørensen, Henrik Toft; Trabert, Britton; Bjørge, Tone (Journal article; Peer reviewed, 2022)
      The experience of pregnancy has a lasting impact, in many cases beneficial, on cancer risk in the mother. In the long term, breast, ovarian, and endometrial cancers are lower in parous women, and each pregnancy provides ...
    • Selective serotonin reuptake inhibitors and venlafaxine in early pregnancy and risk of birth defects: Population based cohort study and sibling design 

      Furu, Kari; Kieler, Helle; Haglund, Bengt; Engeland, Anders; Selmer, Randi; Stephansson, Olof; Valdimarsdottir, Unnur Anna; Zoega, Helga; Artama, Miia; Gissler, Mika; Malm, Heli; Nørgaard, Mette (Peer reviewed; Journal article, 2015)
      Objective To assess whether use of specific selective serotonin reuptake inhibitors (SSRIs) or venlafaxine in early pregnancy is associated with an increased risk of birth defects, with emphasis on cardiovascular birth ...
    • Selective serotonin reuptake inhibitors during pregnancy and risk of persistent pulmonary hypertension in the newborn: population based cohort study from the five Nordic countries 

      Kieler, Helle; Artama, Miia; Engeland, Anders; Ericsson, Örjan; Furu, Kari; Gissler, Mika; Nielsen, Rikke Beck; Nørgaard, Mette; Stephansson, Olof; Valdimarsdottir, Unnur; Zoega, Helga; Haglund, Bengt (Journal article, 2012-01-12)
      Objective: To assess whether maternal use of selective serotonin reuptake inhibitors (SSRIs) increases the risk of persistent pulmonary hypertension in the newborn, and whether such an effect might differ between specific ...