Blar i Bergen Open Research Archive på forfatter "Hanevik, Kurt"
-
Intestinal microbiota and diet in IBS: causes, consequences, or epiphenomena?
Rajilic-Stojanovic, Mirjana; Jonkers, Daisy M; Salonen, Anne; Hanevik, Kurt; Raes, Jeroen; Jalanka, Jonna; de Vos, Willem M; Manichanh, Chaysavanh; Golic, Natasa; Enck, Paul; Elena, Philippou; Iraqi, Fuad A; Clarke, Gerard; Spiller, Robin C; Penders, John (Peer reviewed; Journal article, 2015-01-27)Irritable bowel syndrome (IBS) is a heterogeneous functional disorder with a multifactorial etiology that involves the interplay of both host and environmental factors. Among environmental factors relevant for IBS etiology, ... -
Irritable Bowel Syndrome and Chronic Fatigue 6 Years After Giardia Infection: A Controlled Prospective Cohort Study
Hanevik, Kurt; Wensaas, Knut-Arne; Rørtveit, Guri; Eide, Geir Egil; Mørch, Kristine; Langeland, Nina (Peer reviewed; Journal article, 2014-08-12)Background. Functional gastrointestinal disorders and fatigue may follow acute infections. This study aimed to estimate the persistence, prevalence, and risk of irritable bowel syndrome and chronic fatigue 6 years after ... -
Monocytes from neonates and adults have a similar capacity to adapt their cytokine production after previous exposure to BCG and β-glucan
Namakula, Rhoda; de Bree, L Charlotte J; Tvedt, Tor Henrik Anderson; Netea, Mihai G; Cose, Stephen; Hanevik, Kurt (Journal article; Peer reviewed, 2020-02-21)The Bacillus Calmette-Guérin (BCG) vaccine is administered at birth in tuberculosis (TB) endemic countries. BCG vaccination is also associated with protective non-specific effects against non-tuberculous infections. This ... -
A New Human Challenge Model for Testing Heat-Stable Toxin-Based Vaccine Candidates for Enterotoxigenic Escherichia Coli Diarrhea - Dose Optimization, Clinical Outcomes, and CD4+ T Cell Responses
Sakkestad, Sunniva Todnem; Steinsland, Hans; Skrede, Steinar; Lillebø, Kristine; Skutlaberg, Dag Harald; Guttormsen, Anne Berit; Zavialov, Anton; Paavilainen, Sari; Søyland, Hanne; Sævik, Marianne; Rykkje Heien, Astrid; Gjerde Tellevik, Marit; Barry, Eileen; Langeland, Nina; Sommerfelt, Halvor; Hanevik, Kurt (Peer reviewed; Journal article, 2019-10-30)Enterotoxigenic Escherichia coli (ETEC) are a common cause of diarrheal illness in young children and travelers. There is yet no licensed broadly protective vaccine against ETEC. One promising vaccine development strategy ... -
No difference in serum levels of B-cell activating receptor and antibodies against cytolethal distending toxin B and flagellin in post-infectious irritable bowel syndrome and chronic fatigue syndrome after Giardia infection
Hanevik, Kurt; Saghaug, Christina Skår; Aaland, Maren; Mørch, Kristine; Langeland, Nina (Journal article; Peer reviewed, 2022)Background and Aim Functional gastrointestinal disorders (FGIDs) and chronic fatigue syndrome (CFS) frequently occur as comorbid conditions to each other. A shared etiology of these syndromes has been proposed because of ... -
Novel Insights into the Pathogenesis of Human Post-Primary Tuberculosis from Archival Material of the Pre-Antibiotic Era, 1931–1947
Riaz, Syeda Mariam; Hanevik, Kurt; Helgeland, Lars; Sviland, Lisbet; Hunter, Robert L.; Mustafa, Tehmina (Journal article; Peer reviewed, 2023)Objectives: Primary and post-primary tuberculosis (TB) are distinct entities. The aim of this study was to study the histopathology of primary and post-primary TB by using the unique human autopsy material from the ... -
A novel, single-amplification PCR targeting mitochondrial genome highly sensitive and specific in diagnosing malaria among returned travellers in Bergen, Norway
Haanshuus, Christel Gill; Mohn, Stein Christian; Mørch, Kristine; Langeland, Nina; Blomberg, Bjørn; Hanevik, Kurt (Peer reviewed; Journal article, 2013-01-22)Background: Nested PCR is a commonly used technique in diagnosis of malaria owing to its high sensitivity and specificity. However, it is time-consuming, open to considerable risk of contamination and has low cost-efficiency. ... -
A novel, single-amplification PCR targeting mitochondrial genome highly sensitive and specific in diagnosing malaria among returned travellers in Bergen, Norway
Haanshuus, Christel Gill; Mohn, Stein Christian; Mørch, Kristine; Langeland, Nina; Blomberg, Bjørn; Hanevik, Kurt (Peer reviewed; Journal article, 2013-01-22)Background: Nested PCR is a commonly used technique in diagnosis of malaria owing to its high sensitivity and specificity. However, it is time-consuming, open to considerable risk of contamination and has low cost-efficiency. ... -
Oocyst Shedding Dynamics in Children with Cryptosporidiosis: a Prospective Clinical Case Series in Ethiopia
Johansen, Øystein Haarklau; Abdissa, Alemseged; Bjørang, Ola; Zangenberg, Mike; Sharew, Bizuwarek; Alemu, Yonas; Moyo, Sabrina John; Mekonnen, Zeleke; Langeland, Nina; Robertson, Lucy; Hanevik, Kurt (Journal article; Peer reviewed, 2022)Knowledge on the duration of Cryptosporidium oocyst shedding, and how shedding may be affected by subtypes and clinical parameters, is limited. Reduced transmission may be a secondary benefit of cryptosporidiosis treatment ... -
Perceived food intolerance and irritable bowel syndrome in a population 3 years after a giardiasis-outbreak: a historical cohort study
Litleskare, Sverre; Wensaas, Knut-Arne; Eide, Geir Egil; Hanevik, Kurt; Kahrs, Gudrun E; Langeland, Nina; Rørtveit, Guri (Peer reviewed; Journal article, 2015-11-19)Background: Studies have shown an increased prevalence of irritable bowel syndrome (IBS) after acute gastroenteritis. Food as a precipitating and perpetuating factor in IBS has gained recent interest, but food intolerance ... -
Performance and operational feasibility of two diagnostic tests for cryptosporidiosis in children (CRYPTO-POC): a clinical, prospective, diagnostic accuracy study
Johansen, Øystein Haarklau; Abdissa, Alemseged; Zangenberg, Mike; Mekonnen, Zeleke; Eshetu, Beza; Bjørang, Ola; Alemu, Yonas; Sharew, Bizuwarek; Langeland, Nina; Robertson, Lucy; Hanevik, Kurt (Journal article; Peer reviewed, 2021)Background: Cryptosporidiosis is a common cause of diarrhoea in young children (aged younger than 24 months) in low-resource settings but is currently challenging to diagnose. Light-emitting diode fluorescence microscopy ... -
Plasma levels of guanylins are reduced in patients with Crohn’s disease
Volkmann, Hilde Løland Von; Brønstad, Ingeborg; Tronstad, Rune Rose; Dizdar, Vernesa; Nylund, Kim; Hanevik, Kurt; Hausken, Trygve; Gilja, Odd Helge; Fiskerstrand, Torunn (Journal article; Peer reviewed, 2020)Background: Guanylin (GN) and uroguanylin (UGN) are endogenous ligands for the intestinal receptor guanylate cyclase C (GC-C), an important regulator of intestinal fluid homeostasis. Gene expression and protein levels of ... -
Post epidemic giardiasis and gastrointestinal symptoms among preschool children in Bergen, Norway. A cross-sectional study
Mellingen, Kristin M.; Midtun, Anita; Hanevik, Kurt; Eide, Geir Egil; Søbstad, Øystein; Langeland, Nina (Peer reviewed; Journal article, 2010-03-26)Background A surprisingly low number of children became ill with giardiasis during the large waterborne outbreak of Giardia lamblia in Bergen, Norway during autumn 2004. The aim of the present study was to evaluate the ... -
Post-giardiasis functional gastrointestinal disorders and chronic fatigue syndrome – clinical symptoms, inflammation and immune responses
Hanevik, Kurt (Doctoral thesis, 2012-01-20) -
Postinfectious and sporadic functional gastrointestinal disorders have different prevalences and rates of overlap: results from a controlled cohort study 3 years after acute giardiasis
Wensaas, Knut-Arne; Hanevik, Kurt; Hausken, Trygve; Eide, Geir Egil; Langeland, Nina; Mørch, Kristine; Rørtveit, Guri (Peer reviewed; Journal article, 2016)Background: Irritable bowel syndrome (IBS) is a common complication following gastroenteritis, and a high prevalence of postgiardiasis IBS has previously been reported. This study aims to investigate the prevalence, adjusted ... -
Prevalence and assemblage of Giardia duodenalis in a case-control study of children under 5 years from Jimma, Southwest Ethiopia
Alemu, Yonas; Abdissa, Alemseged; Mekonnen, Zeleke; Sharew, Bizuwarek; Johansen, Øystein Haarklau; Bjørang, Ola; Langeland, Nina; Hanevik, Kurt; Moyo, Sabrina John (Journal article; Peer reviewed, 2023)Giardia duodenalis is a common pathogenic intestinal protozoan parasite with high prevalence in developing countries, especially among children. The distribution of giardia assemblages among humans and their clinical ... -
Prevalence and molecular characterisation of human adenovirus in diarrhoeic children in Tanzania; a case control study
Moyo, Sabrina John; Hanevik, Kurt; Blomberg, Bjørn; Kommedal, Øyvind; Nordbø, Svein Arne; Maselle, Samuel Y; Langeland, Nina (Peer reviewed; Journal article, 2014-12-12)Background: Human adenovirus (HAdV) causes acute diarrhoea sporadically, as well as in outbreaks. Understanding the prevalence and types of HAdV in diarrhoea is important for control and preventive measures, especially in ... -
Prevalence of Cryptosporidium parvum/hominis, Entamoeba histolytica and Giardia lamblia among Young Children with and without Diarrhea in Dar es Salaam, Tanzania
Tellevik, Marit Gjerde; Moyo, Sabrina John; Blomberg, Bjørn; Hjøllo, Torunn; Maselle, Samuel Y; Langeland, Nina; Hanevik, Kurt (Peer reviewed; Journal article, 2015-10-09)Background: Although enteroparasites are common causes of diarrheal illness, few studies have been performed among children in Tanzania. This study aimed to investigate the prevalence of Cryptosporidium parvum/hominis, ... -
Prevalence of fibromyalgia 10 years after infection with Giardia lamblia: a controlled prospective cohort study
Hunskår, Gunnhild Sellevoll; Rørtveit, Guri; Litleskare, Sverre; Eide, Geir Egil; Hanevik, Kurt; Langeland, Nina; Wensaas, Knut-Arne (Journal article; Peer reviewed, 2022)Objectives: To investigate whether acute infection with Giardia lamblia is associated with fibromyalgia 10 years after infection and whether fibromyalgia is associated with irritable bowel syndrome (IBS) and chronic fatigue ... -
Proliferation of enterotoxigenic Escherichia coli strain TW11681 in stools of experimentally infected human volunteers
Vedøy, Oda Barth; Hanevik, Kurt; Sakkestad, Sunniva Todnem; Sommerfelt, Halvor; Steinsland, Hans (Peer reviewed; Journal article, 2018-10-16)Background: As part of the efort to develop an enterotoxigenic Escherichia coli (ETEC) human challenge model for testing new heat-stable toxin (ST)-based vaccine candidates, a controlled human infection model study based ...