Blar i Bergen Open Research Archive på forfatter "Johannessen, Anne Christine"
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Influence of oral mucosal lesions and oral symptoms on oral health related quality of life in dermatological patients: a cross sectional study in Sudan
Suliman, Nada M.; Johannessen, Anne Christine; Ali, Raouf Wahab; Salman, Hussein; Åstrøm, Anne Nordrehaug (Peer reviewed; Journal article, 2012-07-08)Background: There are only few studies considering the impact of oral mucosal lesions (OML) on the oral quality of life of patients with different dermatological conditions. This study aimed to assess the relationship ... -
Integrin a11 is overexpressed by tumour stroma of head and neck squamous cell carcinoma and correlates positively with alpha smooth muscle actin expression
Parajuli, Himalaya; Teh, Muy-Teck; Abrahamsen, Siren; Christoffersen, Ingeborg Monge; Neppelberg, Evelyn; Lybak, Stein; Osman, Tarig Al-Hadi; Johannessen, Anne Christine; Gullberg, Donald; Skarstein, Kathrine; Costea, Daniela Elena (Peer reviewed; Journal article, 2017-04)BACKGROUND: Cancer-associated fibroblasts (CAFs) were shown to be important for tumour progression in head and neck squamous cell carcinomas (HNSCCs). Their heterogeneity and lack of specific markers is increasingly ... -
Isolation and characterization of cells derived from human epithelial rests of Malassez
Kitajima, Kayoko; Das, Ridhima; Liang, Xiao; Neppelberg, Evelyn; Johannessen, Anne Christine; Costea, Daniela Elena; Igarashi, Masaru (Journal article; Peer reviewed, 2019)The epithelial rests of Malassez (ERMs) might represent a valuable source of oral epithelial cells with stem cell properties. The purpose of this study was to isolate and characterize cells derived from human ERM, and ... -
Loss of S100A14 expression at the tumor-invading front correlates with poor differentiation and worse prognosis in oral squamous cell carcinoma
Pandey, Sushma; Osman, Tarig Al-Hadi; Sharma, Sunita; Vallenari, Evan Michael; Shahdafar, Aboulghassem; Pun, Chin B.; Gautam, Dej K.; Uhlin-Hansen, Lars; Rikardsen, Oddveig G; Johannessen, Anne Christine; Costea, Daniela Elena; Sapkota, Dipak (Journal article; Peer reviewed, 2020)Background We previously showed a tumor‐suppressive function of S100A14 in oral squamous cell carcinoma (OSCC). This study aimed to examine the prognostic significance and differentiation‐related function of S100A14 in ... -
The Low Affinity Nerve Growth Factor Receptor p75NTR Identifies a Transient Stem Cell-Like State in Oral Squamous Cell Carcinoma Cells
Osman, Tarig Al-Hadi; Costea, Daniela Elena; Parajuli, Himalaya; Sapkota, Dipak; Johannessen, Anne Christine; Ahmed, Israa A. H. (Peer reviewed; Journal article, 2014-09-12)Background Although several markers have been used for enrichment of cells with stem cell-like properties in oral squamous cell carcinoma (OSCC), isolation of a pure subpopulation is still a challenging task. Normal oral ... -
MicroRNA-138 abates fibroblast motility with effect on invasion of adjacent cancer cells
Rajthala, Saroj; Parajuli, Himalaya; Dongre, Harsh Nitin; Ljøkjel, Borghild; Hoven, Kristin Marie; Kvalheim, Arild; Lybak, Stein; Neppelberg, Evelyn; Sapkota, Dipak; Johannessen, Anne Christine; Costea, Daniela Elena (Journal article; Peer reviewed, 2022-03-17)Background: Recent studies have shown aberrant expression of micro-RNAs in cancer-associated fibroblasts (CAFs). This study aimed to investigate miR-138 dysregulation in CAFs in oral squamous cell carcinoma (OSCC) and its ... -
Mutations of the p53 gene in oral squamous-cell carcinomas from sudanese dippers of nitrosamine-rich toombak and non-snuff-dippers from the Sudan and Scandinavia
Ibrahim, Salah Osman; Vasstrand, Endre N.; Johannessen, Anne Christine; Idris, Ali M.; Magnusson, Bengt; Nilsen, Rune; Lillehaug, Johan (Journal article, 1999-11-08)Using PCR-SSCP/DNA sequencing methods, we analyzed 14 oral squamous-cell carcinomas (OSCCs) and 8 pre-malignant oral lesions from different Sudanese patients for prevalence of mutations in exons 5 to 9 of the p53 gene in ... -
Nanodiamond modified copolymer scaffolds affects tumour progression of early neoplastic oral keratinocytes
Suliman, Salwa; Mustafa, Kamal Babikeir Eln; Krueger, Anke; Steinmüller-Nethl, Doris; Finne-Wistrand, Anna; Osdal, Tereza; Osman, Amani Hamza Ali; Sun, Yang; Parajuli, Himalaya; Waag, Thilo; Nickel, Joachim; Johannessen, Anne Christine; McCormack, Emmet; Costea, Daniela Elena (Peer reviewed; Journal article, 2016-07)This study aimed to evaluate the tumorigenic potential of functionalising poly(LLA-co-CL) scaffolds. The copolymer scaffolds were functionalised with nanodiamonds (nDP) or with nDP and physisorbed BMP-2 (nDP-PHY) to enhance ... -
Oral mucosal lesions in skin diseased patients attending a dermatologic clinic: a cross-sectional study in Sudan
Suliman, Nada M.; Åstrøm, Anne Nordrehaug; Ali, Raouf Wahab; Salman, Hussein; Johannessen, Anne Christine (Peer reviewed; Journal article, 2011-09-19)Background: So far there have been no studies focusing on the prevalence of a wide spectrum of oral mucosal lesions (OML) in patients with dermatologic diseases. This is noteworthy as skin lesions are strongly associated ... -
Peripheral odontogenic keratocyst causing bone resorption: Report of two cases
Loro, Lado Lako; Johannessen, Anne Christine; Skarstein, Kathrine; Hellem, Sølve (Journal article; Peer reviewed, 2023)Two cases of peripheral odontogenic keratocyst (POKC) of the gingiva presenting as asymptomatic nodules are described. The exceptional finding of cystic radiolucency in POKCs was observed on dental radiography in one case, ... -
Primary intraosseous carcinoma arising in a dentigerous cyst: A case report
Tousi, Farnoush; Johannessen, Anne Christine; Ljøkjel, Borghild; Løes, Sigbjørn (Journal article; Peer reviewed, 2023)Dentigerous cysts are among the most common cysts of the jaw. They are attached to the crown of an unerupted tooth, most frequently third molars and maxillary canines. They are often asymptomatic and may therefore be ... -
Profiling and functional analysis of microRNA deregulation in cancer-associated fibroblasts in oral squamous cell carcinoma depicts an anti-invasive role of microRNA-204 via regulation of their motility
Rajthala, Saroj; Min, Anjie; Parajuli, Himalaya; Debnath, Kala Chand; Ljøkjel, Borghild; Hoven, Kristin Marie; Kvalheim, Arild; Lybak, Stein; Neppelberg, Evelyn; Vintermyr, Olav Karsten; Johannessen, Anne Christine; Sapkota, Dipak; Costea, Daniela Elena (Journal article; Peer reviewed, 2021-11-04)Background: Knowledge on the role of miR changes in tumor stroma for cancer progression is limited. This study aimed to investigate the role of miR dysregulation in cancer-associated fibroblasts (CAFs) in oral squamous ... -
Rapid adherence to collagen IV enriches for tumour initiating cells in oral cancer.
Liang, Xiao; Osman, Tarig Al-Hadi; Sapkota, Dipak; Neppelberg, Evelyn; Lybak, Stein; Liavaag, Per Gunnar; Johannessen, Anne Christine; Jacobsen, Hege Karine; Enger, Per Øyvind; Costea, Daniela Elena; Wang, Jian (Peer reviewed; Journal article, 2014-12)Background: Although several approaches for identification and isolation of carcinoma cells with tumour initiating properties have been established, enrichment of a population of pure and viable tumour-initiating cells ... -
A rat model of radiation injury in the mandibular area
Sønstevold, Tonje; Johannessen, Anne Christine; Stuhr, Linda Elin Birkhaug (Peer reviewed; Journal article, 2015-06-09)Background Radiation technology focuses on delivering the radiation as precisely as possible to the tumor, nonetheless both acute and long-term damage to surrounding normal tissue may develop. Injuries to the surrounding ... -
S100A16 promotes differentiation and contributes to a less aggressive tumor phenotype in oral squamous cell carcinoma
Sapkota, Dipak; Bruland, Ove; Parajuli, Himalaya; Osman, Tarig Al-Hadi; Teh, Muy-Teck; Johannessen, Anne Christine; Costea, Daniela Elena (Peer reviewed; Journal article, 2015-09-09)Background: Altered expression of S100A16 has been reported in human cancers, but its biological role in tumorigenesis is not fully understood. This study aimed to investigate the clinical significance and functional role ... -
Successful triple immuno-enzymatic method employing primary antibodies from same species and same immunoglobulin subclass
Osman, Tarig Al-Hadi; Øijordsbakken, Gunnvor; Costea, Daniela Elena; Johannessen, Anne Christine (Peer reviewed; Journal article, 2013-09-16)Protocols for immunohistochemical (IHC) detection of multiple antigens in the same tissue sections have been developed using primary antibodies directly conjugated to different enzymes or fluorochromes, or ones that have ... -
The Swedish Snus and the Sudanese Toombak: are they different?
Idris, Ali M.; Ibrahim, Salah Osman; Vasstrand, Endre N.; Johannessen, Anne Christine; Lillehaug, Johan; Magnusson, Bengt; Wallström, M.; Hirsch, Jan M.; Nilsen, Rune (Journal article, 1998-11)In Sweden, snuff (locally known as snus), was introduced since the year 1637. Presently, Sweden has the highest per capita consumption and sale figures of snuff in the world, and the habit is becoming increasingly popular. ... -
TP53 mutation and human papilloma virus status as independent prognostic factors in a Norwegian cohort of vulva squamous cell carcinoma
Dongre, Harsh Nitin; Elnour, Rammah; Tornaas, Stian; Fromreide, Siren; Thomsen, Liv Cecilie Vestrheim; Kolseth, Ingrid Moss; Nginamau, Elisabeth Sivy; Johannessen, Anne Christine; Vintermyr, Olav Karsten; Costea, Daniela Elena; Bjørge, Line (Journal article; Peer reviewed, 2024)Introduction: Vulva squamous cell carcinoma (VSCC) develops through two separate molecular pathways—one involving high-risk human papilloma virus infection (HPV-associated), and the other without HPV infection (HPV-independent) ... -
X-ray microanalytical studies of initial mineralization in induced heterotopic bone formation in guinea pigs
Johannessen, Anne Christine; Nilsen, Rune; Bang, Gisle (Journal article, 1981)Allogenic demineralized dentin implanted in the abdominal wall of guinea pigs induced heterotopic osteoid and bone formation. Samples of this tissue were frozen at -140° C, freeze-dried at -80° C, infiltrated with Spurr® ...