Blar i Bergen Open Research Archive på forfatter "Kvalheim, Olav Martin"
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The multivariate physical activity signature associated with metabolic health in children
Aadland, Eivind; Kvalheim, Olav Martin; Anderssen, Sigmund Alfred; Resaland, Geir Kåre; Andersen, Lars Bo (Peer reviewed; Journal article, 2018-08-15)Background. Physical activity is a cornerstone for promoting good metabolic health in children, but it is heavily debated which intensities (including sedentary time) are most influential. A fundamental limitation to current ... -
The multivariate physical activity signature associated with metabolic health in children and youth: An International Children's Accelerometry Database (ICAD) analysis
Aadland, Eivind; Kvalheim, Olav Martin; Hansen, Bjørge Hermann; Kriemler, Susi; Ried-Larsen, Mathias; Wedderkopp, Niels; Sardinha, Luis B.; Møller, Niels Christian; Hallal, Pedro C.; Anderssen, Sigmund Alfred; Northstone, Kate; Andersen, Lars Bo (Journal article; Peer reviewed, 2020)There is solid evidence for an association between physical activity and metabolic health outcomes in children and youth, but for methodological reasons most studies describe the intensity spectrum using only a few summary ... -
Number of components and prediction error in partial least squares regression determined by Monte Carlo resampling strategies
Kvalheim, Olav Martin; Grung, Bjørn; Rajalahti, Tarja (Peer reviewed; Journal article, 2019)Using a metabolomics data set with 1057 serum samples, we designed and assessed different procedures based on Monte Carlo resampling schemes to determine the optimal number of components to be included in partial least ... -
Physical activity intensity profiles associated with cardiometabolic risk in middle-aged to older men and women
Dempsey, Paddy C.; Aadland, Eivind; Strain, Tessa; Kvalheim, Olav Martin; Westgate, Kate; Lindsay, Tim; Khaw, Kay-Tee; Wareham, Nicholas J.; Brage, Søren Karl; Wijndaele, Katrien (Journal article; Peer reviewed, 2022)Accelerometers provide detailed data about physical activity (PA) across the full intensity spectrum. However, when examining associations with health, results are often aggregated to only a few summary measures [e.g. time ... -
Predictive associations between serum fatty acids and lipoproteins in healthy non-obese Norwegians: implications for cardiovascular health
Lin, Chenchen; Rajalahti, Tarja; Mjøs, Svein Are; Kvalheim, Olav Martin (Peer reviewed; Journal article, 2016-01)A battery of methods for multivariate data analysis has been used to assess the associations between concentrations of fatty acids (FAs) and lipoprotein subclasses and particle size in serum for a normolipidemic population ... -
Serum fatty acid and lipoprotein subclass concentrations and their associations in prepubertal healthy Norwegian children
Rajalahti, Tarja; Lin, Chenchen; Mjøs, Svein Are; Kvalheim, Olav Martin (Peer reviewed; Journal article, 2016-03)Introduction The lipid metabolism is one of the most important and complex processes in the body. Serum concentrations of 18 fatty acids (FAs) and 24 lipoprotein features, i.e. concentrations of lipoprotein main and ... -
Toxicological evaluation of complex mixtures by pattern recognition: Correlating chemical fingerprints to mutagenicity
Ingvar, Eide; Neverdal, Gunhild; Thorvaldsen, Bodil; Grung, Bjørn; Kvalheim, Olav Martin (Journal article, 2002-12)We describe the use of pattern recognition and multivariate regression in the assessment of complex mixtures by correlating chemical fingerprints to the mutagenicity of the mixtures. Mixtures were 20 organic extracts of ... -
Variable importance: Comparison of selectivity ratio and significance multivariate correlation for interpretation of latent‐variable regression models
Kvalheim, Olav Martin (Journal article; Peer reviewed, 2020)This work examines the performance of significance multivariate correlation (sMC) and selectivity ratio (SR) for ranking variables according to their importance in latent-variable regressions (LVRs) models. Both indices ...