Blar i Bergen Open Research Archive på forfatter "Løberg, Else-Marie"
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Dynamic Functional Connectivity Patterns in Schizophrenia and the Relationship With Hallucinations
Weber, Sarah; Johnsen, Erik; Kroken, Rune Andreas; Løberg, Else-Marie; Kandilarova, Sevdalina; Stoyanov, Drozdstoy; Kompus, Kristiina; Hugdahl, Kenneth (Journal article; Peer reviewed, 2020)There is a wealth of evidence showing aberrant functional connectivity (FC) in schizophrenia but with considerable variability in findings across studies. Dynamic FC is an extension of traditional static FC, in that such ... -
The efficacy of integrated hepatitis C virus treatment in relieving fatigue in people who inject drugs: a randomized controlled trial
Vold, Jørn Henrik; Chalabianloo, Fatemeh; Løberg, Else-Marie; Aas, Christer Frode; Lim, Aaron G.; Vickerman, Peter; Johansson, Kjell Arne; Fadnes, Lars T. (Journal article; Peer reviewed, 2023)Background Most people who inject drugs (PWIDs) suffer from severe fatigue, and chronic hepatitis C virus (HCV) infection may play a role in this. However, there is scarce evidence about interventions that alleviate ... -
Glutamate- and GABA-Modulated Connectivity in Auditory Hallucinations—A Combined Resting State fMRI and MR Spectroscopy Study
Weber, Sarah; Hjelmervik, Helene; Craven, Alexander R.; Johnsen, Erik; Kroken, Rune Andreas; Løberg, Else-Marie; Ersland, Lars; Kompus, Kristiina; Hugdahl, Kenneth (Journal article; Peer reviewed, 2021)Background: Auditory verbal hallucinations (AVH) have been linked to aberrant interhemispheric connectivity between the left and the right superior temporal gyrus (STG), labeled the interhemispheric miscommunication theory. ... -
Hallucinating schizophrenia patients have longer left arcuate fasciculus fiber tracks: a DTI tractography study
Falkenberg, Liv E.; Westerhausen, René; Johnsen, Erik; Kroken, Rune Andreas; Løberg, Else-Marie; Beresniewicz, Justyna; Kazimierczak, Katarzyna Anna; Kompus, Kristiina; Ersland, Lars; Sandøy, Lydia Brunvoll; Hugdahl, Kenneth (Journal article; Peer reviewed, 2020)The arcuate fasciculus (AF) has been implicated in the pathology behind schizophrenia and auditory verbal hallucinations (AVHs). White matter tracts forming the arcuate fasciculus can be quantified and visualized using ... -
Hallucinations in acutely admitted patients with psychosis, and effectiveness of risperidone, olanzapine, quetiapine, and ziprasidone: a pragmatic, randomized study
Johnsen, Erik; Sinkeviciute, Igne; Løberg, Else-Marie; Kroken, Rune A.; Hugdahl, Kenneth; Jørgensen, Hugo A. (Peer reviewed; Journal article, 2013-09-30)Background Hallucinations are prevalent in schizophrenia and related psychotic disorders and may have severe consequences for the affected patients. Antipsychotic drug trials that specifically address the anti-hallucinatory ... -
Health-related quality of life of long-term patients receiving opioid agonist therapy: a nested prospective cohort study in Norway
Aas, Christer Frode; Vold, Jørn Henrik; Skurtveit, Svetlana; Lim, Aaron G.; Ruths, Sabine; Kamrul, Islam; Askildsen, Jan Erik; Løberg, Else-Marie; Fadnes, Lars T.; Johansson, Kjell Arne (Journal article; Peer reviewed, 2020)Background Opioid dependence carries the highest disease burden of all illicit drugs. Opioid agonist therapy (OAT) is an evidence-based medical intervention that reduces morbidity and mortality. There is limited knowledge ... -
How do young adults experience and understand the process of developing a first episode of psychosis? A qualitative exploration
Hansen, Hege Almeland; Stige, Signe Hjelen; Davidson, Larry; Løberg, Else-Marie; Veseth, Marius (Journal article; Peer reviewed, 2023)Background Psychosis is a condition which often starts early in life and leaves a significant mark on a young person’s life. It is usually regarded and discussed from a professional point of view. This study sheds light ... -
Illicit substances detected through high-resolution MS analysis in urine samples are associated with greater symptom burden in patients with psychosis
Skrede, Silje; Berg, Jon Andsnes; Fossan, Kjell Ove; Bartz-Johannessen, Christoffer; Løberg, Else-Marie; Kroken, Rune Andreas; Johnsen, Erik (Journal article, 2021)Background The prevalence of new psychoactive substances (NPS) in acute psychotic patients has not been investigated systematically. We applied a highly sensitive and specific mass spectrometry method for detection of NPS ... -
Impact of childhood trauma on antipsychotic effectiveness in schizophrenia spectrum disorders: A prospective, pragmatic, semi-randomized trial
Mørkved, Nina; Johnsen, Erik; Kroken, Rune Andreas; Winje, Dagfinn; Larsen, Tor Ketil; Thimm, Jens; Rettenbacher, M.A.; Johannesen, C.A. Bartz; Løberg, Else-Marie (Journal article; Peer reviewed, 2022)Antipsychotic medications are generally effective in ameliorating psychotic symptoms in schizophrenia spectrum disorders (SSDs). Identifying predictors associated with poor treatment response is important for a personalized ... -
Impact of clinical and sociodemographic factors on fatigue among patients with substance use disorder: a cohort study from Norway for the period 2016–2020
Vold, Jørn Henrik; Gjestad, Rolf; Aas, Christer Frode; Chalabianloo, Fatemeh; Skurtveit, Svetlana; Løberg, Else-Marie; Johansson, Kjell Arne; Fadnes, Lars T. (Journal article; Peer reviewed, 2020)Background The impact of clinical and sociodemographic factors on fatigue remains unknown among patients with substance use disorders (SUD). This study aims to evaluate fatigue among patients with SUD using a nine-item ... -
Impact of glutamate levels on neuronal response and cognitive abilities in schizophrenia
Falkenberg, Liv Eggset; Westerhausen, René; Craven, Alexander R.; Kroken, Rune A.; Løberg, Else-Marie; Specht, Karsten; Hugdahl, Kenneth (Peer reviewed; Journal article, 2014-04-02)Schizophrenia is characterized by impaired cognitive functioning, and brain regions involved in cognitive control processes show marked glutamatergic abnormalities. However, it is presently unclear whether aberrant neuronal ... -
Impact of liver fibrosis and clinical characteristics on dose-adjusted serum methadone concentrations
Chalabianloo, Fatemeh; Høiseth, Gudrun; Vold, Jørn Henrik; Johansson, Kjell Arne; Kringen, Marianne K.; Dalgard, Olav; Ohldieck, Christian; Druckrey-Fiskaaen, Karl Trygve; Aas, Christer Frode; Løberg, Else-Marie; Bramness, Jørgen Gustav; Fadnes, Lars T. (Journal article; Peer reviewed, 2023)Background: There is limited knowledge on the causes of large variations in serum methadone concentrations and dose requirements. Objectives: We investigated the impact of the degree of liver fibrosis on dose-adjusted ... -
Integrated care of severe infectious diseases to people with substance use disorders; a systematic review
Vold, Jørn Henrik; Aas, Christer Frode; Leiva, Rafael Alexander Mo; Vickerman, Peter; Chalabianloo, Fatemeh; Løberg, Else-Marie; Johansson, Kjell Arne; Fadnes, Lars T. (Peer reviewed; Journal article, 2019)Background: Various integrated care models have been used to improve treatment completion of medications for chronic hepatitis B virus (HBV), chronic hepatitis C virus (HCV), Mycobacterium tuberculosis (TB), and Human ... -
Integrated treatment of hepatitis C virus infection among people who inject drugs: A multicenter randomized controlled trial (INTRO-HCV)
Fadnes, Lars T.; Aas, Christer Frode; Vold, Jørn Henrik; Leiva, Rafael Alexander Mo; Ohldieck, Christian; Chalabianloo, Fatemeh; Skurtveit, Svetlana Ondrasova; Lygren, Ole Jørgen; Dalgard, Olav; Vickerman, Peter; Midgard, Håvard; Løberg, Else-Marie; Johansson, Kjell Arne (Journal article; Peer reviewed, 2021)Background The standard pathways of testing and treatment for hepatitis C virus (HCV) infection in tertiary healthcare are not easily accessed by people who inject drugs (PWID). The aim of this study was to evaluate the ... -
Integrated treatment of hepatitis C virus infection among people who inject drugs: study protocol for a randomised controlled trial (INTRO-HCV)
Fadnes, Lars T.; Aas, Christer Frode; Vold, Jørn Henrik; Ohldieck, Christian; Leiva, Rafael Alexander Mo; Chalabianloo, Fatemeh; Skurtveit, Svetlana; Lygren, Ole Jørgen; Dalgard, Olav; Vickerman, Peter; Midgard, Håvard; Løberg, Else-Marie; Johansson, Kjell Arne (Peer reviewed; Journal article, 2019-11-08)Background: A large proportion of people who inject drugs (PWID) living with hepatitis C virus (HCV) infection have not been treated. It is unknown whether inclusion of HCV diagnostics and treatment into integrated substance ... -
Intra-Regional Glu-GABA vs Inter-Regional Glu-Glu Imbalance: A 1H-MRS Study of the Neurochemistry of Auditory Verbal Hallucinations in Schizophrenia.
Hjelmervik, Helene; Craven, Alexander R.; Sinkeviciute, Igne; Johnsen, Erik; Kompus, Kristiina; Bless, Josef Johann; Kroken, Rune Andreas; Løberg, Else-Marie; Ersland, Lars; Gruner, Eli Renate; Hugdahl, Kenneth (Peer reviewed; Journal article, 2019-10-18)Glutamate (Glu), gamma amino-butyric acid (GABA), and excitatory/inhibitory (E/I) imbalance have inconsistently been implicated in the etiology of schizophrenia. Elevated Glu levels in language regions have been suggested ... -
Left temporal lobe structural and functional abnormality underlying auditory hallucinations in schizophrenia
Hugdahl, Kenneth; Løberg, Else-Marie; Nygård, Merethe (Peer reviewed; Journal article, 2009-05-01)In this article, we have reviewed recent findings from our laboratory, originally presented in Hugdahl et al. (2008) . These findings reveal that auditory hallucinations in schizophrenia should best be conceptualized as ... -
Negative valence of hallucinatory voices as predictor of cortical glutamatergic metabolite levels in schizophrenia patients
Hjelmervik, Helene; Craven, Alexander R.; Johnsen, Erik; Kompus, Kristiina; Bless, Josef Johann; Sinkeviciute, Igne; Kroken, Rune Andreas; Løberg, Else-Marie; Ersland, Lars; Grüner, Eli Renate; Sommer, Iris E.; Hugdahl, Kenneth Jan (Journal article; Peer reviewed, 2021)Objectives Negative emotional valence of auditory verbal hallucinations (AVHs) in schizophrenia can be a source of distress and is considered a strong predictor of illness severity. Previous studies have found glutamate ... -
Neural activation in the ventromedial prefrontal cortex precedes conscious experience of being in or out of a transient hallucinatory state
Hugdahl, Kenneth; Craven, Alexander R.; Johnsen, Erik; Ersland, Lars; Stoyanov, Drozdstoy; Kandilarova, Sevdalina; Sandøy, Lydia Brunvoll; Kroken, Rune A.; Løberg, Else-Marie; Sommer, Iris E. (Journal article; Peer reviewed, 2022)Background and Hypotheses Auditory verbal hallucinations (AVHs) is not only a common symptom in schizophrenia but also observed in individuals in the general population. Despite extensive research, AVHs are poorly understood, ... -
‘Not at all what I had expected’: Discontinuing treatment with extended-release naltrexone (XR-NTX): A qualitative study
Brenna, Ida Halvorsen; Marciuch, Anne; Birkeland, Bente; Veseth, Marius; Røstad, Bente; Løberg, Else-Marie; Solli, Kristin Klemmetsby; Tanum, Lars Håkon Reiestad; Weimand, Bente (Journal article; Peer reviewed, 2022)Background: Extended-release naltrexone (XR-NTX), an opioid antagonist, has demonstrated equal treatment outcomes, in terms of safety, opioid use, and retention, to the recommended OMT medication buprenorphine. However, ...