• Nucleated red blood cells explain most of the association between DNA methylation and gestational age 

      Haftorn, Kristine Løkås; Denault, William Robert Paul; Lee, Yunsung; Page, Christian Magnus; Romanowska, Julia; Lyle, Robert; Næss, Øyvind Erik; Kristjansson, Dana; Magnus, Per Minor; Håberg, Siri Eldevik; Bohlin, Jon; Jugessur, Astanand (Journal article; Peer reviewed, 2023)
      Determining if specific cell type(s) are responsible for an association between DNA methylation (DNAm) and a given phenotype is important for understanding the biological mechanisms underlying the association. Our EWAS of ...
    • Risk of attention‐deficit hyperactivity disorder in offspring of mothers with infections during pregnancy 

      Walle, Kjersti Mæhlum; Askeland, Ragna Bugge; Gustavson, Kristin; Mjaaland, Siri; Ystrøm, Eivind; Lipkin, W. Ian; Magnus, Per Minor; Stoltenberg, Camilla; Susser, Ezra; Bresnahan, Michaeline; Hornig, Mady; Reichborn-Kjennerud, Ted; Ask, Helga (Journal article; Peer reviewed, 2022)
      Background Maternal infections during pregnancy are common events that have been suggested to be risk factors for Attention-deficit hyperactivity disorder (ADHD) in offspring. Only a few studies have been conducted to ...
    • Smoking and infertility: multivariable regression and Mendelian randomization analyses in the Norwegian Mother, Father and Child Cohort Study 

      Hernáez, Álvaro; Wootton, Robyn E; Page, Christian Magnus; Skåra, Karoline Hansen; Fraser, Abigail; Rogne, Tormod; Magnus, Per Minor; Njølstad, Pål Rasmus; Andreassen, Ole; Burgess, Stephen; Lawlor, Deborah A.; Magnus, Maria Christine (Journal article; Peer reviewed, 2022)
      Objective To investigate the association between smoking and infertility. Design Prospective study. Setting Nationwide cohort. Patients 28,606 women and 27,096 men with questionnaire and genotype information ...
    • Stability selection enhances feature selection and enables accurate prediction of gestational age using only five DNA methylation sites 

      Haftorn, Kristine Løkås; Romanowska, Julia; Lee, Yunsung; Page, Christian Magnus; Magnus, Per Minor; Håberg, Siri Eldevik; Bohlin, Jon; Jugessur, Astanand; Denault, William Robert Paul (Journal article; Peer reviewed, 2023)
      Background: DNA methylation (DNAm) is robustly associated with chronological age in children and adults, and gestational age (GA) in newborns. This property has enabled the development of several epigenetic clocks that can ...
    • Titers of antibodies against ancestral SARS-CoV-2 correlate with levels of neutralizing antibodies to multiple variants 

      Tran, Trung The; Vaage, Eline Benno; Mehta, Adi; Chopra, Adity; Tietze, Lisa; Kolderup, Anette; Anthi, Aina Karen; König, Marton; Nygaard, Gro Owren; Lind, Andreas; Müller, Fredrik; Nissen-Meyer, Lise Sofie Haug; Magnus, Per Minor; Trogstad, Lill; Mjaaland, Siri; Søraas, Arne Vasli; Midtvedt, Karsten; Åsberg, Anders; Barratt-Due, Andreas; Medhus, Asle Wilhelm; Høivik, Marte Lie; Lundin, Knut; Karlsen, Randi Fuglaas; Dahle, Reidun; Danielsson, Karin; Thomassen, Kristine Stien; Kro, Grete Anette Birkeland; Cox, Rebecca Jane; Zhou, Fan; Langeland, Nina; Aukrust, Pål; Melum, Espen; Åvitsland, Tone Lise; Wiencke, Kristine; Holter, Jan Cato; Munthe, Ludvig Andre; Grødeland, Gunnveig; Andersen, Jan Terje; Vaage, John T.; Lund-Johansen, Fridtjof (Journal article; Peer reviewed, 2022)
      Diagnostic assays currently used to monitor the efficacy of COVID-19 vaccines measure levels of antibodies to the receptor-binding domain of ancestral SARS-CoV-2 (RBDwt). However, the predictive value for protection against ...
    • Within-sibship genome-wide association analyses decrease bias in estimates of direct genetic effects 

      Howe, Laurence J.; Nivard, Michel G.; Morris, Tim T.; Hansen, Ailin Falkmo; Rasheed, Humaira; Cho, Yoonsu; Chittoor, Geetha; Ahlskog, Rafael; Lind, Penelope A.; Palviainen, Teemu; van der Zee, Matthijs D.; Cheesman, Rosa Catherine Gillespie; Mangino, Massimo; Wang, Yunzhang; Li, Shuai; Klaric, Lucija; Ratliff, Scott M.; Bielak, Lawrence F.; Nygaard, Marianne; Giannelis, Alexandros; Willoughby, Emily A.; Reynolds, Chandra A.; Balbona, Jared V.; Andreassen, Ole; Ask, Helga; Baras, Aris; Bauer, Christopher R.; Boomsma, Dorret I.; Campbell, Archie; Campbell, Harry; Chen, Zhengming; Christofidou, Paraskevi; Corfield, Elizabeth Claire; Dahm, Christina C.; Dokuru, Deepika R.; Evans, Luke M.; de Geus, Eco J. C.; Giddaluru, Sudheer; Gordon, Scott D.; Harden, K. Paige; Hill, W. David; Hughes, Amanda; Kerr, Shona M.; Kim, Yongkang; Kweon, Hyeokmoon; Latvala, Antti; Lawlor, Deborah A.; Li, Liming; Lin, Kuang; Magnus, Per Minor; Magnusson, Patrik K. E.; Mallard, Travis T.; Martikainen, Pekka; Mills, Melinda C.; Njølstad, Pål Rasmus; Overton, John D.; Pedersen, Nancy L.; Porteous, David J.; Reid, Jeffrey; Silventoinen, Karri; Southey, Melissa C.; Stoltenberg, Camilla; Tucker-Drob, Elliot M.; Wright, Margaret J.; Kweon, Hyeokmoon; Koellinger, Philipp D.; Benjamin, Daniel J.; Turley, Patrick; Howe, Laurence J.; Nivard, Michel G.; Morris, Tim T.; Plomin, Robert; Havdahl, Alexandra; Bartels, Meike; Martin, Nicholas G.; Oskarsson, Sven; Justice, Anne E.; Millwood, Iona Y.; Hveem, Kristian; Naess, Øyvind; Willer, Cristen J.; Åsvold, Bjørn Olav; Kaprio, Jaakko; Medland, Sarah E.; Walters, Robin G.; Evans, David M.; Smith, George Davey; Hayward, Caroline; Brumpton, Ben; Hemani, Gibran; Davies, Neil Martin; Hewitt, John K.; Keller, Matthew C.; Stallings, Michael C.; Lee, James J.; Christensen, Kaare; Kardia, Sharon L. R.; Peyser, Patricia A.; Smith, Jennifer A.; Wilson, James F.; Hopper, John L.; Hägg, Sara; Spector, Tim D.; Pingault, Jean-Baptiste; Næss, Øyvind Erik; Davey Smith, George; Brumpton, Ben Michael (Journal article; Peer reviewed, 2022)
      Estimates from genome-wide association studies (GWAS) of unrelated individuals capture effects of inherited variation (direct effects), demography (population stratification, assortative mating) and relatives (indirect ...
    • The X-factor in ART: does the use of assisted reproductive technologies influence DNA methylation on the X chromosome? 

      Romanowska, Julia; Nustad, Haakon Egdetveit; Page, Christian Magnus; Denault, William Robert Paul; Lee, Yunsung; Magnus, Maria Christine; Haftorn, Kristine Løkås; Gjerdevik, Miriam; Novakovic, Boris; Saffery, Richard; Gjessing, Håkon K.; lyle, robert; Magnus, Per Minor; Håberg, Siri Eldevik; Jugessur, Astanand (Journal article; Peer reviewed, 2023)
      Background Assisted reproductive technologies (ART) may perturb DNA methylation (DNAm) in early embryonic development. Although a handful of epigenome-wide association studies of ART have been published, none have investigated ...